Results 51 to 60 of about 26,412 (249)

Mechanisms in the pathogenesis of poststroke spasticity

Неврология, нейропсихиатрия, психосоматика, 2011
Objective: to study the mechanisms of poststroke spasticity and the role of structural and functional impairments of skeletal muscles in its pathogenesis. Patients and methods.
E. A. Katushkina, O. E. Zinovyeva, B. S. Shenkman, N. N. Yakhno   +3 more
doaj   +1 more source

Dynamic analysis of CSF1R-related leukoencephalopathy on magnetic resonance imaging: a case report

BMC Neurology, 2021
Background Colony-stimulating factor 1 receptor (CSF1R)-related leukoencephalopathy is a rare and rapidly progressive leukoencephalopathy characterized by cognitive, motor, and neuropsychiatric symptoms, which is often misdiagnosed.
Huasheng Huang, Liming Cao, Hong Chen
doaj   +1 more source

A Comparative Study of Diffusion Fiber Reconstruction Models for Pyramidal Tract Branches

Frontiers in Neuroscience, 2021
Currently, comparative studies evaluating the quantification accuracy of pyramidal tracts (PT) and PT branches that were tracked based on four mainstream diffusion models are deficient.
Xinjun Suo, Xinjun Suo, Xinjun Suo, Lining Guo, Lining Guo, Dianxun Fu, Dianxun Fu, Hao Ding, Hao Ding, Yihong Li, Wen Qin, Wen Qin   +11 more
doaj   +1 more source

Alterações encontradas por ressonância magnética na esclerose lateral amiotrófica utilizando sequência spin-echo com transferência de magnetização: relato preliminar [PDF]

, 1999
We present the magnetic resonance (MR) findings of five patients with amyotrophic lateral sclerosis (ALS) using a spin-echo sequence with an additional magnetization transfer (MT) pulse on T1-weighted images (T1 SE/MT).
Lederman, Henrique Manoel, Maia Junior, Antonio Carlos Martins, Nogueira, Roberto Gomes, Rocha, Antônio José   +3 more
core   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Preliminary study on the protective effect of intraoperative direct electrical stimulation motor⁃evoked potential on brainstem motor function

Chinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective Preliminary study on the protective effect of intraoperative direct electrical stimulation motor ⁃ evoked potential (DES ⁃ MEP) on motor function during brainstem tumor surgery.
Xiao⁃rong TAO, Ming⁃ran WANG, Rong WANG, Zhi⁃bao LI, Xing FAN, Li⁃wei ZHANG, Hui QIAO   +6 more
doaj  

Swimming in Deep Water: Zebrafish Modeling of Complicated Forms of Hereditary Spastic Paraplegia and Spastic Ataxia

Frontiers in Neuroscience, 2019
Hereditary spastic paraplegia (HSP) and hereditary ataxia (HA) are two groups of disorders characterized, respectively, by progressive dysfunction or degeneration of the pyramidal tracts (HSP) and of the Purkinje cells and spinocerebellar tracts (HA ...
Valentina Naef, Serena Mero, Serena Mero, Gianluca Fichi, Gianluca Fichi, Angelica D'Amore, Angelica D'Amore, Angelica D'Amore, Asahi Ogi, Asahi Ogi, Federica Gemignani, Filippo M. Santorelli, Maria Marchese   +12 more
doaj   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

Advanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield, Katarzyna A. Grzelak, Katie Katsuyama, Vardhman Kumar, Bess M. Miller, Joa Yun, Jesse Kirkpatrick, David Mankus, Margaret E. Bisher, Abigail K.R. Lytton‐Jean, Z. Gordon Jiang, David D. Lee, Christopher S. Chen, Sangeeta N. Bhatia   +13 more
wiley   +1 more source

A rare case of ispilateral hemiparesis in a patient with uncrossed pyramidal tract shown by tractography

Radiology Case Reports
This article presents a unique case of ipsilateral hemiparesis in a 66-year-old individual, contrary to the conventional understanding of supratentorial strokes causing contralateral neurological deficits.
Manal Jidal, MD, Kenza Horache, MD, Meriem Fikri, MD PhD, Najwa El Kettani, MD PhD, Mohammed Jiddane, MD PhD, Firdaous Touarsa, MD PhD   +5 more
doaj   +1 more source

Parkinsonism in Association with Dihydropteridine Reductase Deficiency

Case Reports in Neurology, 2017
We report a 16-year-old man with disorders of tetrahydrobiopterin metabolism due to dihydropteridine reductase (DHPR) deficiency. He revealed moderate mental retardation, parkinsonism, and spastic paralysis with levodopa and 5-hydroxytryptophan (5-HTP ...
Yoshiaki Takahashi, Yasuhiro Manabe, Yumiko Nakano, Taijun Yunoki, Syoichiro Kono, Hisashi Narai, Mahoko Furujo, Koji Abe   +7 more
doaj   +1 more source