Results 51 to 60 of about 13,686 (260)
Chinese Journal of Contemporary Neurology and Neurosurgery, 2020 Objective Preliminary study on the protective effect of intraoperative direct electrical stimulation motor ⁃ evoked potential (DES ⁃ MEP) on motor function during brainstem tumor surgery.
Xiao⁃rong TAO +6 more
doaj
Frontiers in Neuroscience, 2019 Hereditary spastic paraplegia (HSP) and hereditary ataxia (HA) are two groups of disorders characterized, respectively, by progressive dysfunction or degeneration of the pyramidal tracts (HSP) and of the Purkinje cells and spinocerebellar tracts (HA ...
Valentina Naef +12 more
doaj +1 more source
Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Advanced Science, EarlyView.Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
A 3D In Vitro Model of the Human Hepatobiliary Junction
Advanced Science, EarlyView.A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield +13 more
wiley +1 more source
Parkinsonism in Association with Dihydropteridine Reductase Deficiency
Case Reports in Neurology, 2017 We report a 16-year-old man with disorders of tetrahydrobiopterin metabolism due to dihydropteridine reductase (DHPR) deficiency. He revealed moderate mental retardation, parkinsonism, and spastic paralysis with levodopa and 5-hydroxytryptophan (5-HTP ...
Yoshiaki Takahashi +7 more
doaj +1 more source
, 1986 Axons of the adult mammalian CNS typically fail to regenerate after injury. Among the hypotheses to account for this failure is the proposition that certain axonal proteins necessary for axon growth are expressed in much greater abundance in developing ...
JH Skene, K Kalil
core +1 more source
Brain imaging correlates of recovered swallowing after dysphagic stroke: A fMRI and DWI study
NeuroImage: Clinical, 2016 Neurogenic dysphagia frequently occurs after stroke and deglutitive aspiration is one of the main reasons for subacute death after stroke. Although promising therapeutic interventions for neurogenic dysphagia are being developed, the functional ...
Paul Glad Mihai +5 more
doaj +1 more source
Characteristic Magnetic Resonance Image Features of Acute Network Injury in Young Patients
Case Reports in Neurology, 2021 Cerebral infarction is known to cause secondary degeneration of the areas connected to the primarily damaged regions. This has been named as acute network injury and is usually recognized in newborns or babies by high signal intensity on diffusion ...
Sohyeon Kim +4 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.In this study, we established a novel mouse model of intracerebral hemorrhage (ICH) by stereotactically injecting thermosensitive PNIPAM hydrogel into the internal capsule to impose localized mechanical stress on the corticospinal tract, which provides a straightforward and reproducible tool for preclinical studies on focal mechanical stress–induced ...
Mingxi Li +11 more
wiley +1 more source
Frontiers in NeurologyA stroke can damage various regions of the brain. Damage to the upper motor neurons of the pyramidal tracts causes unilateral upper motor neuron dysarthria or spastic dysarthria.
Lan-Xin Lin +13 more
doaj +1 more source