Discrimination of roast and ground coffee aroma [PDF]
, 2012 Background: Four analytical approaches were used to evaluate the aroma profile at key stages in roast and ground coffee brew preparation (concentration within the roast and ground coffee and respective coffee brew; concentration in the headspace of the
AM Costa Freitas +29 more
core +3 more sources
Tetrahydropyrazolo[1,5-a]Pyrimidine-3-Carboxamide and N-Benzyl-6′,7′-Dihydrospiro[Piperidine-4,4′-Thieno[3,2-c]Pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3 [PDF]
, 2013 Mycobacterium tuberculosis is a major human pathogen and the causative agent for the pulmonary disease, tuberculosis (TB). Current treatment programs to combat TB are under threat due to the emergence of multi-drug and extensively-drug resistant TB.
A Hill +48 more
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Repurposing the KCa3.1 inhibitor senicapoc for Alzheimer's disease. [PDF]
, 2019 ObjectiveMicroglia play a pivotal role in the initiation and progression of Alzheimer's disease (AD). We here tested the therapeutic hypothesis that the Ca2+-activated potassium channel KCa3.1 constitutes a potential target for treating AD by reducing ...
Bushong, Trevor +8 more
core +2 more sources
Consecutive reactions with sulfoximines: a direct access to 2-sulfonimidoylylidene tetrahydrofurans and 6-sulfonimidoylmethyl- 3,4-dihydro-2H-pyrans [PDF]
, 2009 International audience2-Sulfonimidoylylidene tetrahydrofurans and 2-sulfonimidoylylidene-5-vinyl tetrahydrofurans were readily synthesized via a consecutive acylation/SN2 sequence with total regio- and chemoselectivity from Johnson's sulfoximine ...
Bonne, Damien +8 more
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Primary investigation into the occurrence of Hydroxymethylfurfural (HMF) in a range of smoked products [PDF]
, 2018 5-hydroxymethylfurfural (HMF) is produced in foods through many different pathways. Recently, studies have revealed its potential mutagenic and carcinogenic properties.
Bouzalakou-Butel, Laura-Artemis +3 more
core +2 more sources
Litter Quality of Populus Species as Affected by Free-Air CO2 [PDF]
, 2009 The effect of elevated CO2 and nitrogen fertilization on the molecular chemistry of litter of three Populus species and associated soil organic matter (SOM) was investigated by pyrolysis-gas chromatography/mass spectrometry.
Buurman, P., Hoosbeek, M.R., Vermue, E.
core +4 more sources
A convenient domino access to substituted alkyl 1,2-dihydropyridine- 3carboxylates from propargyl enol ethers and primary amines [PDF]
, 2016 A convenient domino access to substituted alkyl 1,2-dihydropyridine-3- carboxylates from propargyl enol ethers and primary amines was reported. A solution of propargyl sinyl ether 1a and p-anisidine in toluene was placed in a microwave-special closed ...
García-Tellado, Fernando +2 more
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An acido- and photochromic molecular device that mimics triode action [PDF]
, 2016 © The Royal Society of Chemistry 2016. The photo-controlled shift of pH titration curves, describing the acidochromic behaviour of a spiropyran switch network, was harnessed for the realisation of a molecular triode.
Andréasson, Joakim +4 more
core +1 more source
Advanced Physics Research, EarlyView.A light‐responsive system with photochromism and excitation‐dependent phosphorescence was constructed by microwave synthesis of nitrogen‐doped carbon dots(N‐CDs), which provides insights into the design and synthesis of CDs with multifunctional optical properties, promoting the application expansion of intelligent responsive materials in the fields of ...
Xiaoqi Fang +7 more
wiley +1 more source
Metal-mediated intramolecular hydroamination and hydro(acy)alkoxylation reactions [PDF]
, 2012 This PhD thesis describes work undertaken to effect asymmetric catalysis in hydroamination and hydro(acy)alkoxylation reactions of allenes. The introductory Chapter provides an overview of recent advances in asymmetric heterofunctionalisation reactions ...
Arbour, Jannine Louise +1 more
core +1 more source