Results 91 to 100 of about 13,031 (233)

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

open access: yesChemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato   +3 more
wiley   +1 more source

Membrane‐Permeable Nucleoside T‐1106 Diphosphate and Triphosphate Analogues as Antiviral Pronucleotides

open access: yesChemistry – A European Journal, EarlyView.
Favipiravir (T‐705) and the non‐fluorinated counterpart (T‐1106) are antiviral agents that inhibit the RNA‐dependent RNA polymerase (RdRp) of various RNA viruses. The antiviral efficacy of nucleoside analogues is strongly dependent on their intracellular activation by cellular kinases to produce their corresponding triphosphate metabolites (T‐705‐RTP ...
Chris Meier   +7 more
wiley   +1 more source

Recent Advances in Photocatalytic Urea Synthesis via C−N Coupling From C/N‐Containing Species: A Mini Review

open access: yesEcoEnergy, EarlyView.
This review systematically compares photocatalytic urea synthesis from various C (CO2, CO, CH3OH) and N (N2, NH3, NO3−) sources. It highlights C–N coupling mechanisms, key challenges, and future directions, offering a framework to guide rational catalyst design for sustainable, solar‐driven urea production.
Bo Ding   +5 more
wiley   +1 more source

Ligand‐Level Chemical Activation: Coordination with Benefits

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
While often perceived as a liability, ligand‐based reactivity in carefully designed settings becomes a powerful synthetic tool. The key to streamlined processes overriding classical ionic reactivity is the selective electron redistribution induced by metal coordination. This enables storage of electrons and protons or incorporation of functional groups
Oscar Charpentier   +2 more
wiley   +1 more source

Characterization of Cantaloupe, Grape, Pumpkin, and Tomato Seed Oils From Xinjiang: Oxidative Stability, Volatile‐Compound Analysis, and Sensory Evaluation

open access: yesFood Chemistry International, EarlyView.
This study compares oxidative stability, fatty acid profiles, volatile compounds, and sensory attributes of four Xinjiang seed oils. Distinct aldehyde‐driven aroma patterns and compositional differences were revealed, providing a scientific basis for quality evaluation and valorization of underutilized plant seed oils in food applications.
Yilai Wan   +4 more
wiley   +1 more source

Spirobifluorene fusion in multiple resonance frameworks enables efficient pure‐red OLEDs with narrowband emission and suppressed efficiency roll‐off

open access: yesFlexMat, EarlyView.
An orthogonal spirobifluorene‐fusion strategy is introduced for B/N/O‐alternated MR frameworks, enabling improved kRISC (5.46 × 103 s−1), high ΦPL (97%), and narrow‐band pure‐red emission. Vacuum‐evaporated OLEDs incorporating this emitter achieve an EQEmax >40% (FWHM = 36 nm) and exhibit exceptionally low efficiency roll‐off at high luminance ...
Yan‐Yun Jing   +7 more
wiley   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

open access: yesFood Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng   +5 more
wiley   +1 more source

Micellar Suzuki–Miyaura Reaction With Xylose Acetal Cosolvents: A Life Cycle Assessment Approach

open access: yesHelvetica Chimica Acta, EarlyView.
Biomass‐derived solvents (xylose acetals DFX and DPX, and Solvinol) were evaluated for micellar Suzuki–Miyaura reactions in water. High efficiency at low loadings, combined with simplified solvent removal—especially for DFX—reduced solvent waste and environmental impact.
Arian Bajramaj   +7 more
wiley   +1 more source

C–H Annulation in Azines to Obtain 6,5-Fused-Bicyclic Heteroaromatic Cores for Drug Discovery

open access: yesReactions
Fused-bicyclic heteroaromatic cores are a common framework in drugs and other biologically active compounds. Those containing azine rings are widely used in drug discovery campaigns.
Maria Carolina Theisen   +3 more
doaj   +1 more source

Drought Risk in Mango and Avocado Orchards: Insights Into Plant Water Relations and Irrigation‐Related Agronomic Solutions

open access: yesIrrigation and Drainage, EarlyView.
ABSTRACT Climate change is making water availability more uncertain, with growing consequences for the productivity and long‐term sustainability of tropical and subtropical fruit orchards. Mangifera indica L. and Persea americana Mill. both require large amounts of water to sustain growth and productivity.
Eleonora Cataldo
wiley   +1 more source

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