Results 91 to 100 of about 1,014,531 (338)

Metabolomic investigation of cisplatin‐induced acute kidney injury in paediatric cancer patients

British Journal of Clinical Pharmacology, EarlyView.
Aim Cisplatin causes acute kidney injury (AKI) in approximately 46% of paediatric cancer patients who receive it. Serum creatinine (SCr) is a poor biomarker of cisplatin nephrotoxicity, because there is a delay between cisplatin infusion and SCr elevation.
Yong Jin Lim, Amy Thachil, Kelly McMahon, Ross T. Tsuyuki, S. Rod Rassekh, Lesley G. Mitchell, Prasad Devarajan, Cherry Mammen, Bruce C. Carleton, Geoffrey D. E. Cuvelier, Victor A. Lewis, Colin J. D. Ross, Alexandra P. Zorzi, Sylvain Baruchel, Raveena Ramphal, Eric Bouffet, Mathieu Lemaire, Tom D. Blydt‐Hansen, Brad L. Urquhart, The Applying Biomarkers to Minimize Long‐Term Effects of Childhood/Adolescent Cancer Treatment (ABLE) Research Study Group, Tom Blydt‐Hansen, Bruce C. Carleton, Geoff D. E. Cuvelier, Sunil Desai, Prasad Devarajan, Conrad Fernandez, Adam Fleming, Paul Gibson, Caroline Laverdiere, Victor Lewis, Mary L. McBride, Bruno Michon, Shahrad Rod Rassekh, Colin J. D. Ross, Christine Sabapathy, Kirk R. Schultz, Michael Zappitelli, Alexandra Zorzi   +37 more
wiley   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

Bulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon, Hyemin Yoon, Kang Ju Lee, Hyun Jin Kim   +3 more
wiley   +1 more source

COMPLEX COMPOUNDS OF BIPOSITIVE SILVER WITH PYRIDINE CARBOXYLIC ACIDS. PART III. ARGENTIC COMPOUNDS OF PYRIDINE TRICARBOXYLIC ACIDS

, 1957
In continuation of the previous work on silver(II) complexes of pyridine mono- and dicarboxylic acids it has now been possible to prepare the argentic complexes of some of the pyridine tricarboxylic acids, namely pyridine-2 :3:6-, -2:4:5, and -2 :4 :6-carboxylic acids. Argentic complexes of all the three acids were obtained by the persulphate oxidation
BIRESWAR BANERJEE, PRIYADARANJAN RAY
openaire   +2 more sources

Infrared Spectra of Pyrazine-and Pyridine-carboxylic Acid and Their Derivatives.

Chemical and Pharmaceutical Bulletin, 1959
Infrared absorption spectra of pyridine- and pyrazine-carboxylic acids have following characteristic absorptions. 1) There are broad absorption bands with peaks at 2450 and 1900 cm-1. The former shifts to around 1900 cm-1 by deuteration but the latter does not. 2) Absorptions for O-H in-plane deformation and C-O stretching vibration are present at 1340∼
Yoshida, Shigeru, Asai, Motoji
openaire   +2 more sources

Glycosylated dendrimer nanoamplifiers hijack DNA damage‐immune crosstalk for enhanced dual‐track therapy of orthotopic glioblastoma

BMEMat, EarlyView.
A glycosylated dendrimer nanoamplifier hijacks DNA damage‐immune crosstalk for enhanced radio‐immunotherapy of glioblastoma. The responsive release of demethylcantharidin simultaneously blocks repair‐mediated resistance by inhibiting DNA repair and overcomes adaptive immune resistance.
Cong Song, Binghan Liu, Junjie Liu, Ce Li, Wenqing Man, Xurui Sun, Chang Yuan, Yanjun Wang, Hong Pan, Shuanglian Wang, Zhiming Zheng   +10 more
wiley   +1 more source

Engineering Halide Perovskites With Chalcogen‐Based Compounds: Insights Into Stability, Interfaces, and Device Integration

Carbon Energy, EarlyView.
Chalcogen‐based compounds are explored as versatile tools to enhance the stability and performance of halide perovskites. Their roles in defect passivation, ion migration suppression, and interface engineering are analyzed, along with impacts on device efficiency.
Atanu Jana, Deblina Das, Sourav Mal, Tarak Nath Mandal, Sangeun Cho   +4 more
wiley   +1 more source

A Convergent Materials Design Paradigm Across Electro‐ and Photocatalysis for Sustainable Hydrogen Peroxide Production

Carbon Energy, EarlyView.
This review outlines advanced modification strategies for electrocatalytic and photocatalytic H2O2 production, covering bandgap tuning, defect engineering, heterostructure construction, cocatalyst loading, and functional framework design. Structure‐performance correlations are revealed across catalysts such as metal oxides, sulfides, carbon nitrides ...
Na Li, Jie Zhou, Yazhou Zhou, Zhen Yang, Yufeng Wang, Bo Weng, Jinyang Chen, Mingchao Shao, Minfeng Zeng, Wei Zong   +9 more
wiley   +1 more source

Complicated Composting: Persistent Pyridine Carboxylic Acid Herbicides

, 2013
This paper reviews pyridine carboxylic acid herbicide impacts on compost. Pyridine carboxylic acid herbicides are not completely broken down during grass growth, harvest and drying of hay, in the digestive tract of livestock, or during composting.
Reimer, Julie
core  

Multivalent RNA‐Cleaving Agents on a Cubic Octameric Silsesquioxane Core

Chemistry – A European Journal, EarlyView.
RNA‐cleaving agents on a cubic octameric silsesquioxane core were synthesized and characterized. Several catalytic systems of these structures were screened using hexaribonucleotide models. The best systems were then further used to study their catalytic efficiency in cleaving a HER2 mRNA model sequence. The induced cleavage sites were also determined.
Hanni Haapsaari, Iris Tuomi, Pasi Virta
wiley   +1 more source

Perspectives on Synthetic Adducts (Salts) of Nitroxoline^TM and 2-Aminoquinolin-8-ol as Promising Antibacterial Agents

Chemistry Proceedings
The threatening phenomenon of antibiotic failure in the future determines the intensive research of antibacterial active compounds, which are promising candidates as antibiotics.
Tibor Maliar, Renata Gašparová, Mária Maliarová   +2 more
doaj   +1 more source