Results 141 to 150 of about 24,216 (244)

A Neutral “Masked” Diborene and Its Reactivity Toward Metal‐Free Pyridine Homocoupling

Angewandte Chemie, EarlyView.
An unprecedented neutral “masked” diborene, formed via intramolecular arene dearomatization of an N‐heterocyclic imine‐supported free diborene, can be photochemically released to regenerate the highly reactive triplet diborene intermediate. Computational analysis elucidates the bonding situation of the hitherto elusive free diborene species, and the ...
Ke Li, Arseni Kostenko, John A. Kelly, Tobias Weng, Shigeyoshi Inoue   +4 more
wiley   +1 more source

Imidazo[1,2‑<i>a</i>]pyridines in Medicinal Chemistry: Recent Advances in Synthesis and Biological Activities. [PDF]

ACS Omega
Ferreira LAP, Caruso L, Nadur NF, Franco DP, Sousa GLS, Lacerda RB, Kümmerle AE.   +6 more
europepmc   +1 more source

Fluorogenic Coupled Assays Reveal Catalytic Properties, Inhibition Constants and Cellular Location of Mucin‐Active Carbohydrate Sulfatases

Angewandte Chemie, EarlyView.
We report plate‐based coupled assays to rapidly and quantitatively determine the activity and selectivity of mucin‐active carbohydrate sulfatases. This fluorogenic assay further enables inhibitor identification and allows determination of (sub‐)cellular location. ABSTRACT Sulfated glycans play a central role in human health and influence cell signaling,
Charles W. E. Tomlinson, Madouc D. Bergers, David N. Bolam, Ana S. Luis, Alan Cartmell, Zachary Armstrong   +5 more
wiley   +1 more source

Click-to-Release Reactions for Tertiary Amines and Pyridines. [PDF]

J Am Chem Soc
Chojnacki K, Demuth T, Faulkner J, Guo P, Bansal P, Arshad H, English J, Peterson RT, Svatunek D, Franzini RM.   +9 more
europepmc   +1 more source

Valency‐Controlled Multiphotochromism: Gated Switching and Photoswitchable Lewis Superacidity at Silicon

Angewandte Chemie, EarlyView.
Multiphotochromic switching is controlled by silicon valency in a diarylethene‐based molecular architecture. Lewis base coordination gates electronic communication between the photochromic units, thereby enabling selective access to distinct switching states.
Lennart Stoess, Valentin D. Hannibal, Lutz Greb   +2 more
wiley   +1 more source

Net Oxidative Photocatalytic Strategy toward the <i>o</i>-Trifluoroacetylation of <i>N</i>-Heteroarenes. [PDF]

Org Lett
Samony KL, Thullaprambil JZ, Nabi RN, Brunner KE, Kim DK.   +4 more
europepmc   +1 more source

Antiaromaticity‐Driven Enhancement of Single‐Molecule Electrical Conductance by s‐Indacene Molecular Bridges

Angewandte Chemie, EarlyView.
Within the same molecular length scale, antiaromatic s‐indacene exhibits a marked increase in conductance compared to its aromatic benzodithiophene counterpart. Notably, the inherently small HOMO–LUMO gap of antiaromatic systems maintains a certain level of conductance even in the presence of cross‐conjugation.
Ching‐Piao Chu, Yuki Hanamura, Tatsuhiko Ohto, Seiya Maeda, Ryo Yamada, Siao‐Lei Yu, Yen‐Ju Cheng, Hirokazu Tada, Yoshito Tobe   +8 more
wiley   +1 more source

Synthesis and antimitotic activity of 2-phenyl-6-pyridinyl-2<i>H</i>-pyrazolo[4,3-<i>c</i>]pyridines. [PDF]

RSC Adv
Aleksienė V, Řezníčková E, Bieliauskas A, Vojáčková V, Molitorová V, Šalvytė-Nikliauzienė A, Belyakov S, Žukauskaitė A, Arbačiauskienė E, Kryštof V, Šačkus A.   +10 more
europepmc   +1 more source

Carbohydrate Physicochemical Properties: The Innate Hydrogen Bond Donating Capacities of α‐Glucoside and α‐Galactoside Alcohol Groups

Angewandte Chemie, EarlyView.
Experimental determination of the innate hydrogen bond donating capacities of the glucose and galactose non‐anomeric alcohols revealed significant variations depending on position and relative configuration, which were quantified on the pKAHY scale, relevant for MedChem purposes, hence providing another tool toward rational glycomimetic development ...
Mrinal Naskar, Zhong Wang, Krunal Patel, Branko De Baets, Anaïs Goupille, Davy Sinnaeve, Eric Renault, Jean‐Yves Le Questel, Bruno Linclau   +8 more
wiley   +1 more source

Photochemical C4-Selective C-H Amination of Quinolines via <i>N</i>-Shift of Heteroaryl Azides. [PDF]

Org Lett
Dimasi A, Montoli A, Macetti G, Lo Presti L, Passarella D, Fasano V.   +5 more
europepmc   +1 more source