Regiodivergent C3 and C4 Amination of Quinolines via Radical and Ionic Pathways
A regiodivergent strategy converts a single N‐aminoquinolinium precursor into either C3‐ or C4‐aminated quinolines. Nucleophile‐induced dearomatization diverges into light‐driven N‐centered radical capture (C3) or base‐promoted SNAr (C4), enabling rapid assembly of aminoquinoline libraries and late‐stage diversification.
Ye‐Eun Kim +3 more
wiley +2 more sources
Couple-close: Unified approach to semisaturated cyclic scaffolds. [PDF]
Xie J +9 more
europepmc +1 more source
Depolymerization and Reuse of Polycarbonates: Emerging Classes, Mechanisms and Challenges
This review collects the latest developments in the area of chemical and catalytic polycarbonate recycling strategies and includes the controlled degradation of similar types of macromolecules. Apart from the main strategies for deconstruction, the key mechanistic features of these depolymerization processes are also discussed together with the ...
Davide Rigo +4 more
wiley +2 more sources
London Dispersion versus Intramolecular Hydrogen Bond in Bis-Pyridines: How Accurate Is DFT for Competing Noncovalent Interactions in the Condensed Phase? [PDF]
Savoy A, Gorbachev V, Stindt CN, Chen P.
europepmc +1 more source
Photoenzymatic Hydroalkylation Enables Streamlined Access to Aryl Glutarimide Precursors
We report a photoenzymatic hydroalkylation that enables streamlined, stereocontrolled access to aryl glutarimide precursors relevant to targeted protein degradation. Engineered flavin‐dependent “ene”‐reductases provide broad scope and high enantioselectivity through a distinct electron transfer–enantioselective proton transfer pathway.
Zhi Xu +9 more
wiley +2 more sources
DDQ-promoted synthesis of 2-benzoylbenzofurans and benzofuro[2,3-<i>c</i>]pyridines using 2'-hydroxy ethyl cinnamate and phenacyl bromides. [PDF]
Saini SM +3 more
europepmc +1 more source
It may seem counterintuitive to first target a ruthenium alkylidyne when Grubbs‐type ruthenium carbene complexes are the actual goal. In the end, however, this tactic pays valuable dividends in terms of practicality, atom economy, flexibility as well as safety: the new route provides ready access to a large assortment of catalysts for alkene metathesis
Mingxu Cui, Alois Fürstner
wiley +2 more sources
Photocatalytic construction of <i>N</i>-acyl-<i>N</i>,<i>O</i>-acetal-linked pyridines <i>via</i> aminocyclopropane ring opening. [PDF]
Kim D, Yang E, Cho Y, Hong S.
europepmc +1 more source

