Results 221 to 230 of about 210,328 (345)

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

Advanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao, Jianming Lv, Yue Zhong, Zhiqin Cao, Rui Luo, Yue Qi, Gaoqian Wang, Shaoyang Li, Guodong Chen, Dan Hu, Hao Gao, Xinsheng Yao   +11 more
wiley   +1 more source

Functionalization of Pyridines at the C4 Position via Metalation and Capture. [PDF]

Angew Chem Int Ed Engl
Hsu HH, Kang S, Chen CC, Sk MR, Thomas AA.   +4 more
europepmc   +1 more source

Amperometric Determination of Pyridine with Copper in the Presence of Thiocyanate

, 1955
Makoto Munemori
openalex   +2 more sources

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

Advanced Science, EarlyView.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu, Kai Tang, Jiahui Zhou, Gabriel Pino‐Peco, Nerea López‐Carrobles, Raquel Bello‐Morales, Daniel Galdo‐Torres, Lina Zhang, Federico Gago, José Antonio López‐Guerrero, Xinyong Liu, Peng Zhan, Luis Menéndez‐Arias   +12 more
wiley   +1 more source

Impact of Fluorine Pattern on Lipophilicity and Acid-Base Properties of 2-(Thiofluoroalkyl)pyridines: Insights from Experiments and Statistical Modeling. [PDF]

J Med Chem
Bernús M, Núñez GD, Hartley WC, Guasch M, Mestre J, Besora M, Carbó JJ, Boutureira O.   +7 more
europepmc   +1 more source

Electronic Structures od the Heterocyclic Compounds. I. Ultra-violet Absorption Spectra of Pyridine Derivatives.

, 1957
坪村 宏
openalex   +2 more sources

CuCo‐Layered Double Hydroxide Nanosheets Grown on Hierarchical Carbonized Wood as Bifunctional Electrode for Supercapacitor and Hydrogen Evolution Reaction

Advanced Science, EarlyView.
The N/P co‐doped carbonized wood (NPCW) with open channels is used as the carrier, and in situ uniformly grown copper nanoparticles (Cu NPs) as nucleation centers to induce the vertical growth of CuCo‐LDH nanosheets along the substrate, forming a “carbon‐metal‐LDH” tertiary conductive network, which realizes the synergistic enhancement of high ...
Hewei Hou, Guiqing Lei, Huashuang Huo, Yuanyuan Yu, Zhenzhen Tang, Chengrong Qin, Douyong Min   +6 more
wiley   +1 more source

Synthesis of Thieno[2,3-c]pyridine Derivatives by 1,2,3-Triazole-Mediated Metal-Free Denitrogenative Transformation Reaction. [PDF]

ChemistryOpen
Eroğlu K, Tahir Günkara Ö, Dehaen W.
europepmc   +1 more source

Experiments on the synthesis of the pyridine analogue of vitamin B₁ (aneurin)

, 1940
Rita Harriet Harradence, Francis Lions
openalex   +2 more sources

Single Mitochondrion Morphology‐Function Relationship Analysis Using Fluorescent Probes and Artificial Intelligence

Advanced Science, EarlyView.
An integrated strategy combining a mitochondria‐targeted fluorescent probe set and an AI framework enables simultaneous analysis of mitochondrial morphology and function at the single organelle level. By fusing multi‐parametric features, machine learning classification accurately distinguishes individual mitochondria under hypoxia‐related conditions ...
Yang Ding, Bin Fang, Qingzhe Li, Biying Zhang, Jintao Li, Hua Bai, Nicolas H. Voelcker, Bo Peng, Xuekang Yang, Lin Li   +9 more
wiley   +1 more source