Results 261 to 270 of about 205,200 (319)

C3-Selective Trifluoromethylthiolation and Difluoromethylthiolation of Pyridines and Pyridine Drugs via Dihydropyridine Intermediates.

Journal of the American Chemical Society, 2022
Herein, we report a method for unprecedented C3-selective C-H tri- and difluoromethylthiolation of pyridines. The method relies on borane-catalyzed pyridine hydroboration for generation of nucleophilic dihydropyridines; these intermediates react with ...
Xin-Yue Zhou, Ming Zhang, Zhong Liu, Jiayao He, Xiao‐Chen Wang   +4 more
semanticscholar   +1 more source

Enantioselective C2-H Alkylation of Pyridines with 1,3-Dienes via Ni-Al Bimetallic Catalysis.

Journal of the American Chemical Society, 2022
A chiral phosphine oxide-ligated Ni-Al bimetallic catalyst was used to realize an enantioselective C2-H alkylation of pyridines without the need of a C2-block.
Jiangting Li, Deng Pan, Hao Wang, Tao Zhang, Yi Li, Genping Huang, Mengchun Ye   +6 more
semanticscholar   +1 more source

Visible-Light-Enabled Trifluoromethylative Pyridylation of Alkenes from Pyridines and Triflic Anhydride.

Angewandte Chemie, 2020
A general strategy for visible-light-enabled site-selective trifluoromethylative pyridylation of unactivated alkenes has been developed using pyridines and triflic anhydride (Tf 2 O).
Kangjae Lee, Seojin Lee, Namhoon Kim, Seonyul Kim, Sungwoo Hong   +4 more
semanticscholar   +1 more source

Recent Developments in Transition-Metal-Free Functionalization and Derivatization Reactions of Pyridines

Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry, 2020
Pyridine is an important structural motif that is prevalent in natural products, drugs, and materials. Methods that functionalize and derivatize pyridines have gained significant attention. Recently, a large number of transition-metal-free reactions have
Fei Zhou, Lei Jiao
semanticscholar   +1 more source

Regio- and Enantioselective C-H Cyclization of Pyridines with Alkenes Enabled by a Nickel/N-Heterocyclic Carbene Catalysis.

Journal of the American Chemical Society, 2019
Annulated pyridines are ubiquitous scaffolds in many bioactive molecules. A highly regio- and enantioselective Ni(0)-catalyzed endo-selective C-H cyclization of pyridines with alkenes has been developed.
Wu-Bin Zhang, Xin-Tuo Yang, Junning Ma, Z. Su, Shi‐Liang Shi   +4 more
semanticscholar   +1 more source

SESQUITERPENE PYRIDINE ALKALOIDS

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Redox-Divergent Synthesis of Fluoroalkylated Pyridines and 2-Pyridones through Cu-Catalyzed N-O Cleavage of Oxime Acetates.

Angewandte Chemie, 2018
Cu-catalyzed redox-divergent [3+3] coupling of oxime esters with β-CF3 enones and acrylates is described. This redox-neutral coupling with enones and acrylates affords trifluoromethylated pyridines and pyridones, respectively. Under reductive conditions,
Dachang Bai, Xueli Wang, G. Zheng, Xingwei Li   +3 more
semanticscholar   +1 more source

Pyridines

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +1 more source

Recent advances in the chemistry of thieno[2,3-b]pyridines 1. Methods of synthesis of thieno[2,3-b]pyridines

Russian chemical bulletin, 2020
V. Dotsenko, D. S. Buryi, D. Lukina, S. Krivokolysko   +3 more
semanticscholar   +1 more source

Pyridine

IARC monographs on the evaluation of carcinogenic risks to humans, 2001
  +5 more sources