Results 151 to 160 of about 47,136 (264)

Practical Enantioselective Approach to 3‐Amino‐2‐Hydroxy Acids and Application to the Synthesis of Natural Products

Chirality, Volume 38, Issue 7, July 2026.
A practical and straightforward approach to optically active erythro 3‐amino‐2‐hydroxy acids and its application to the enantioselective synthesis of 3‐phenylisoserine and of the marine natural product 3‐amino‐2‐hydroxy‐6‐methylheptanoic acid is reported.
Marilena Caporale, Giulia Marsico, Ernesto Santoro, Patrizia Scafato, Stefano Superchi   +4 more
wiley   +1 more source

Pyridine and pyridinium-based anion receptors

, 2010
Pyridine and pyridinium heterocycles play an important role in anion receptor chemistry. Hydrogen bond arrays are frequently preorganized by the presence of the pyridine nitrogen lone pair of electrons, whilst the positively charged pyridinium group is ...
Nathan Kilah (14741152), Beer, PD (15571769)   +1 more
core  

Multi‐Targeting Ligands as Prospective Therapeutics for Alzheimer's Disease, a Prevalent Neurodegenerative Disorder: Mechanistic Insights, Emerging Targets and Drug Discovery Campaigns

Medicinal Research Reviews, Volume 46, Issue 4, Page 1173-1229, July 2026.
ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur, Mandeep Rana, Sakshi Vanjani, Kei‐Chi Liou, Rajeev Taliyan, Kunal Nepali, Chih‐Hao Yang   +6 more
wiley   +1 more source

Pyridinium halide promoted ring-opening reactions of exo-norbornene oxide

, 1983
Ring opening of 1 with pyridinium chloride or pyridinium iodide in chloroform and/or pyridine gives significant amounts of halohydrins 2a or 2b, reflecting partial suppression of the Wagner-Meerwein rearrangement that occurs on ring-opening with hydrogen
G. Gargaro, PELLACANI, Lucio, LORETO, Maria Antonietta, TARDELLA, Paolo Antonio   +3 more
core  

Exploring Polyene Construction Tactics for the Total Synthesis of Ocular Pyridinium Bisretinoids of Lipofuscin A2E and pdA2E. [PDF]

J Org Chem
Vidal B, Martínez C, Álvarez R, de Lera ÁR.   +3 more
europepmc   +1 more source

Radiolabeled Angiopep‐2 Peptide Vector as a Preclinical Platform for Blood–Brain Barrier Targeting: Synthesis, Radiolabeling, and Preliminary In Vivo Biodistribution in Mice

Journal of Peptide Science, Volume 32, Issue 7, July 2026.
The developed DOTA‐Angiopep‐2 conjugate was well tolerated in glioma cells and enabled high‐yield radiolabeling with 177Lu and 161Tb. The 161Tb conjugate showed brain delivery with predominantly renal clearance, supporting a stable radiotheranostic platform for BBB‐targeted glioma therapy and SPECT imaging.
Evgenia Fotou, Adamantia Apostolopoulou, Christina‐Georgia Bika, Maria Giannakopoulou, Danai‐Efraimia Bajwa, Vassilios Moussis, Vassilios Tsikaris, Ioannis P. Gerothanassis, George A. Alexiou, Penelope Bouziotis, Andreas G. Tzakos   +10 more
wiley   +1 more source

Pyridinium cationic lipids as gene transfer agents

, 2004
Pyridinium cationic lipids useful as non-viral gene delivery agents are disclosed. The agents are prepared by reaction of pyrylium salts with primary amines.
Seitz, William A., Wentz, Melissa J., Johnson, Betty H., Ilies, Marc A. C., Thompson, Edward Bradbridge, Garfield, Robert E., Balaban, Alexandru T., Miller, Aaron L.   +7 more
core  

Quaternary Carbons from Amines and Acids. [PDF]

J Am Chem Soc
Zhao R, Wang S, Shi P, Das SK, Meng S, Lei A, Cernak T.   +6 more
europepmc   +1 more source

Transfer Learning‐Guided Discovery of Advanced Tetrametallic Single‐Cluster Catalysts for Urea Electrosynthesis

Rare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT Developing advanced electrocatalysts for urea synthesis is pivotal to alleviating environmental burdens as well as advancing sustainability in the industrial and agricultural sectors, yet untargeted catalyst screening still suffers from the notorious drawbacks of being time‐consuming, labor‐intensive, and inefficient.
Xinyuan Yang, Xiuzhen Fan, Ruochen Zhu, Haoyu Wang, Ziyao Ren, Hao Liu, Yubo Ge, Xuchuan Jiang, Riming Hu   +8 more
wiley   +1 more source

Designer Aromatic Cations for Photoinduced Protein Ligation, Imaging, and Intracellular Labeling at Extended Wavelengths. [PDF]

J Am Chem Soc
Saha PC, Solanke PR, Biswas S, Agarwal V, Taylor MT.   +4 more
europepmc   +1 more source