Results 21 to 30 of about 5,613 (180)
3,4-Dihydro-2(1H)-Pyridones as Building Blocks of Synthetic Relevance
Molecules, 2022 3,4-Dihydro-2(1H)-pyridones (3,4-DHPo) and their derivatives are privileged structures, which has increased their relevance due to their biological activity in front of a broad range of targets, but especially for their importance as synthetic precursors
Sisa Chalán-Gualán +5 more
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Synthesis of Some New Enaminoketones, Analogous of Milrinone, 4,Pyrones and Related 4-Pyridones [PDF]
Iranian Journal of Chemistry & Chemical Engineering, 1996 Synthesis of 4-(N,N- dimethylamino)-3-aryl-3-butene-2-one, ethyl-5-aryl-4-oxo-4H-pyran-2-carboxylate, ethyl-5-aryl-4-pyridones-2-carboxylate and 5-aryl-3-cyano-5-methyl-2-pyridones (aryl=3-thienyl, 2-furyl) are described.
Aziz Shahrisa, Salar Hemmati
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Diversity-oriented functionalization of 2-pyridones and uracils
Nature Communications, 2021 Diversity-oriented synthesis of 2-pyridone and uracil derivatives is in urgent need in medicinal chemistry as they are useful pharmacophores. Here the authors show that palladium/norbornene cooperative catalysis enabled dual-functionalization of ...
Yong Shang +8 more
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Synthesis of Some Novel Heterocyclic and Schiff Base Derivatives as Antimicrobial Agents
Molecules, 2015 Treatment of 2,3-diaryloxirane-2,3-dicarbonitriles 1a–c with different nitrogen nucleophiles, e.g., hydrazine, methyl hydrazine, phenyl hydrazine, hydroxylamine, thiosemicarbazide, and/or 2-amino-5-phenyl-1,3,4-thiadiazole, afforded pyrazole, isoxazole ...
Mohamed E. Azab +2 more
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Continuous flow synthesis of some 6- and 1,6-substituted 3-cyano-4-methyl-2-pyridones [PDF]
Journal of the Serbian Chemical Society, 2019 In this study, six 6- and 1,6-substituted-3-cyano-4-methyl-2-pyridones were synthesized in a continuous flow microreactor system. The syntheses were realized at room temperature and the obtained results were compared to those achieved within classical ...
Tadić Julijana +3 more
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Crystal structure of 2,6-dimethyl-4-pyridone hemihydrate
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound (systematic name: 2,6-dimethyl-1H-pyridin-4-one hemihydrate), C7H9NO·0.5H2O, has a single planar molecule in the asymmetric unit with the non-H atoms possessing a mean deviation from planarity of 0.021 Å.
Dalena M. Nguyen +3 more
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CHIMIA, 2020 N-Heterocyclic carbenes (NHCs) are the ligands of choice in a large variety of transformations entailing different transition metals. However, the number and variety of chiral NHCs suitable as stereo-controlling ligands in asymmetric catalysis remains ...
Johannes Diesel, Nicolai Cramer
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SynOpen, 2021 An efficient method for the synthesis of highly substituted bicyclic pyridone derivatives containing the dithiocarbamate group is reported via a one-pot three-component reaction of 2-(alkylthio)thioazlactones, diamines, and nitroketene dithioacetal in ...
Marziyeh Saeedi +6 more
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Pyridonderivate aus 3-Amino-2H-azirinen und Cyclopropenonen
CHIMIA, 1978 Reaction of the 3-dimethylamino-2H-azirines 1a and 1b with diphenylcyclopropenone (2a) in ether or acetonitrile leads to the 2-dimethylamino-5,6-diphenyl-4(3H)-pyridones 3a and 3b in 70 and 80% yield, respectively. The structure of these 1:1-adducts has
Stanislav Chaloupka, Heinz Heimgartner
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Synthesis of 5-Aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones
Molbank, 2023 A two-stage synthesis of 5-aroyl-2-aryl-3-hydroxypyridin-4(1H)-ones (56–66% overall yields) was carried out by refluxing 5-aroyl-3-(benzyloxy)-2-(het)aryl-4H-pyran-4-ones with ammonium acetate in AcOH and subsequent debenzylation.
Elena V. Steparuk +2 more
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