Two New Antibiotic Pyridones Produced by a Marine Fungus, Trichoderma sp. Strain MF106 [PDF]
, 2014 Two unusual pyridones, trichodin A (1) and trichodin B (2), together with the known compound, pyridoxatin (3), were extracted from mycelia and culture broth of the marine fungus, Trichoderma sp. strain MF106 isolated from the Greenland Seas.
Bin Wu +9 more
core +2 more sources
Enzymatic synthesis of vitamin B6 precursor [PDF]
, 2013 3-Cyano-4-ethoxymethyl-6-methyl-2-pyridone is an important precursor in the synthesis of vitamin B6, obtained in the addition reaction between 2-cyanoacetamide and 1-ethoxy-2,4-pentanedione catalyzed by lipase from Candida rugosa ...
Bezbradica Dejan I. +4 more
core +1 more source
Die Acylierung von 4‐Pyridon [PDF]
Chemische Berichte, 1980 AbstractBei der Acylierung von 4‐Pyridon (1) mit aliphatischen Carbonsäure‐anhydriden und ‐chloriden oder freien Säuren in Gegenwart von Dicyclohexylcarbodiimid erhält man ausschließlich N‐Acyl‐4‐pyridone (5). Auch bei der Umsetzung von 1 mit ortho‐substituierten Benzoesäurederivaten sind nur N‐Acylierungsprodukte 8 isolierbar.
Effenberger, Franz +2 more
openaire +1 more source
Efficient synthesis of novel thieno[3,2-b]-, [2,3-c]- and [3,2-c]pyridones by Sonogashira coupling of bromothiophenes with terminal alkynes and subsequent intramolecular C-N bond-forming reaction [PDF]
, 2013 The coupling of bromothiophenes with terminal alkynes using triethylamine or diisopropyl amine under Sonogashira conditions (PdCl2(PPh 3)2, CuI) followed by subsequent addition of amines or ammonium to the intermediate thienyl acetylenes represents a ...
Abbasi, M. S. A. +7 more
core +1 more source
Waltherione C and cleomiscosin from Melochia umbellata var. Degrabrata K. (Malvaceae), biosynthetic and chemotaxonomic significance [PDF]
, 2014 Waltherione C, a 4-quinolinone secondary metabolite, and cleomiscosin have been isolated from Melochia umbellata (Malvaceae).A biosynthetic scheme incorporating the unique 4-pyridones and 4-quinolones isolated from Melochia and Waltheria spp.
Noor, Alfian, Soekamto, Nunuk H.
core +1 more source
Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds
Hemijska industrija, 2014 2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications. In this paper, the synthesis of 2-pyridones as well as 2-pyridone based compounds such as 2-quinolones using microwave assisted organic chemistry is reviewed.
Dusan Mijin +3 more
openaire +4 more sources
SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis. [PDF]
, 2017 Pericyclic reactions-which proceed in a concerted fashion through a cyclic transition state-are among the most powerful synthetic transformations used to make multiple regioselective and stereoselective carbon-carbon bonds.
Chen, Mengbin +9 more
core +1 more source
Organometallic catalysis for applications in radical chemistry and asymmetric synthesis [PDF]
, 2014 Two organometallic catalysis studies are presented. The first one deals with the development of a new catalytic agent based on the mixture of a hydride and an iron salt to trigger efficient radical cyclization processes.
Ateywiohrera +17 more
core +3 more sources
Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview
Chemistry – A European Journal, EarlyView.The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati +4 more
wiley +1 more source
Addition of dianions of carboxylic acids to imines. Influence of the acid in the outcome of the reaction [PDF]
, 2009 The addition of different carboxylic acids dianions to N-benzylidenebenzeneamine have been studied. The outcome of the reaction depends on the acid. Saturated ones lead to β-aminoacids with good yields and syn-selectivity whereas α,β-unsaturated ones ...
Gil Grau, Salvador +2 more
core +1 more source