Results 21 to 30 of about 7,788 (207)

STRUCTURE OF PYRIDONES, PYRIMIDONES, AND THEIR CATIONS.

, 1965
STRUCTURE OF PYRIDONES, PYRIMIDONES, AND THEIR ...
JAMES PRIEST. SHOFFNER (7967351)
core   +6 more sources

A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes

mBio, 2023
Listeria monocytogenes is a facultative Gram-positive bacterium that causes listeriosis, a severe foodborne disease. We previously discovered that ring-fused 2-pyridone compounds can decrease virulence factor expression in Listeria by binding and ...
Hasan Tükenmez, Pardeep Singh, Souvik Sarkar, Melike Çakır, Ana H. Oliveira, Cecilia Lindgren, Karolis Vaitkevicius, Mari Bonde, A. Elisabeth Sauer-Eriksson, Fredrik Almqvist, Jörgen Johansson   +10 more
doaj   +1 more source

Inductive Production of the Iron-Chelating 2-Pyridones Benefits the Producing Fungus To Compete for Diverse Niches

mBio, 2021
Diverse 2-pyridone alkaloids have been identified with an array of biological and pharmaceutical activities, including the development of drugs. However, the biosynthetic regulation and chemical ecology of 2-pyridones remain largely elusive.
Bo Chen, Yanlei Sun, Shiqin Li, Ying Yin, Chengshu Wang   +4 more
doaj   +1 more source

Synthesis and Characterization of New 3-Cyano-2-Pyridone Derivatives as Fluorescent Scaffolds

Chemistry Proceedings, 2023
2-pyridones are among the most widely used nitrogen-containing heterocyclic derivatives in various fields due to their structural properties and biological and therapeutic activities.
Asmaa Kebaili, Fatima Belhadj, Zahira Kibou, Julio A. Seijas, M. Pilar Vazquez Tato, Noureddine Choukchou-Braham   +5 more
doaj   +1 more source

The Construction of Polycyclic Pyridones via Ring-Opening Transformations of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones

Molecules, 2023
This work describes the synthesis of 3-hydroxy-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,8-diones, their tautomerism, and reactivity towards binucleophiles. These molecules are novel and convenient building-blocks for the direct construction of biologically
Viktoria V. Viktorova, Elena V. Steparuk, Dmitrii L. Obydennov, Vyacheslav Y. Sosnovskikh   +3 more
doaj   +1 more source

Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones

, 2021
Reaction of thiazoline fused 2-pyridones with alkyl halides in the presence of cesium carbonate opens the thiazoline ring via S-alkylation and generates N-alkenyl functionalized 2-pyridones.
Pardeep Singh (294895), Anders Olofsson, Dan E. Adolfsson, Jörgen Ådén (1820980), Anna Gharibyan (11690453), Jaideep B. Bharate (1724008), Mohit Tyagi (5279360), Anders Olofsson (343002), Anna Gharibyan, Pardeep Singh, Sanduni Wasana Jayaweera, Souvik Sarkar (1595272), Jörgen Ådén, Dan E. Adolfsson (6483089), Fredrik Almqvist (698391), Fredrik Almqvist, Sanduni Wasana Jayaweera (9560817), Anita Kiss (5564309), Jaideep B. Bharate, Anita Kiss, Mohit Tyagi, Souvik Sarkar   +21 more
core   +1 more source

13C- and 1H-NMR substituent-induced chemical shifts in N(1)-(4-substituted phenyl)-3-cyano-4,6-dimethyl-2-pyridones [PDF]

Journal of the Serbian Chemical Society, 2008
The 13C- and 1H-NMR chemical shifts of thirteen N(1)-(4-substituted phenyl)-3-cyano-4,6-dimethyl-2-pyridones were measured in deuterated dimethyl sulfoxide (DMSO-d6). The correlation analysis for the substituent-induced chemical shifts (SCS) with sigmap,
BRATISLAV Z. JOVANOVIC, GORDANA G. USCUMLIC, DUSAN Z. MIJIN, NATASA V. VALENTIC, ALEKSANDAR D. MARINKOVIC   +4 more
doaj   +3 more sources

Photoredox Catalyzed Radical Cascade Aroylation (Sulfonylation)/Cyclization Enables Access to Fused Indolo-pyridones

, 2021
A visible-light-initiated radical cascade reaction toward the synthesis of structurally diverse fused Indolo-pyridones is described. The reaction involves the addition of aroyl or sulfonyl radicals to N-alkyl-acryloyl-1H-indole-3-carboxamides ...
Zhi Guan (620291), Liang Liu (50022), Jia-Yi Gu, Zhi Guan, Yan-Hong He (620294), Jia-Yi Gu (11797625), De-Yong Yang, Liang Liu, Yan-Hong He, De-Yong Yang (9333256)   +9 more
core   +1 more source

Synthesis and reactivity of novel ONN- and ONO-palladium(II) pincer complexes; applications in CH-halogenation of aryl-pyridones

, 2017
In this thesis, a library of novel unsymmetrical tridentate NNO- and ONO'-type ligands are synthesized and complexed with sources of palladium(II) with a view to exploring the reactivity of the so-formed pincer complexes and their role in CH-halogenation.
Amandeep Singh (3511400)
core   +7 more sources

Recent advances in chemistry and pharmacological aspects of 2-pyridone scaffolds

Journal of Saudi Chemical Society, 2021
Background: The chemistry and applications of 2-pyridone structures have recently attracted a lot of attention due to their uses as synthetic intermediates and their biological importance.
Mostafa M.K. Amer, Maged A. Aziz, Wesam S. Shehab, Magda H. Abdellattif, Samar M. Mouneir   +4 more
doaj   +1 more source