Results 41 to 50 of about 7,788 (207)
Crystal structure of 2,6-dimethyl-4-pyridone hemihydrate
Acta Crystallographica Section E: Crystallographic Communications, 2015 The title compound (systematic name: 2,6-dimethyl-1H-pyridin-4-one hemihydrate), C7H9NO·0.5H2O, has a single planar molecule in the asymmetric unit with the non-H atoms possessing a mean deviation from planarity of 0.021 Å.
Dalena M. Nguyen +3 more
doaj +1 more source
, 2013 The Michael addition and three-component cyclization reaction of amines, alkynes and dialkyl acetylene dicarboxylates to form pyridones has been developed.
Wu, Fan +5 more
core +1 more source
Chemistry – A European Journal, EarlyView.Quinolin‐4‐ones were converted to chloroquinolinium salts, allowing formation of axially chiral aminoquinolinium salts via an enantioretentive SNAr reaction with a variety of amine nucleophiles. The salts have a high rotational barrier, with a racemization half‐life of ∼1000s of years.
Darren Holmes +5 more
wiley +1 more source
Streamlining the Synthesis of Pyridones through Oxidative Amination [PDF]
Herein we report the development of an oxidative amination process for the streamlined synthesis of pyridones from cyclopentenones. Cyclopentenone building blocks can undergo in situ silyl enol ether formation, followed by the introduction of a nitrogen ...
Florian, Ruepp +5 more
core +2 more sources
Recent Progress in Nitro-Promoted Direct Functionalization of Pyridones and Quinolones
Molecules, 2020 Nitro group is one of the most important functional groups in organic syntheses because its strongly electron-withdrawing ability activates the scaffold, facilitating the reaction with nucleophilic reagents or the Diels−Alder reaction.
Feiyue Hao, Nagatoshi Nishiwaki
doaj +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A novel core‐shell HEA@MXene composite was synthesized to enhance supercapacitor electrochemistry. DFT simulations reveal the role of HEA doping in regulating the MXene interface. The HEA@MXene composite exhibits a high specific capacitance of 872 F g−1 at 1 A g−1 with remarkable stability in 1 M KOH.
Fenhong Song +8 more
wiley +1 more source
An Isomünchnone-Based Method for the Synthesis of Highly Substituted 2(1H)-Pyridones
, 2016 1-(Benzenesulfonyl-diazoacetyl)-pyrrolidin-2-one was prepared by a diazo transfer of 1-(benzenesulfonylacetyl)-pyrrolidin-2-one with p-acetamidobenzenesulfonyl azide and triethylamine.
Albert Padwa (1676569) +2 more
core +1 more source
Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles
Angewandte Chemie, Volume 138, Issue 35, 24 August 2026.Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley +2 more sources
Selective N‐Functionalization of Pyrazoles
European Journal of Organic Chemistry, EarlyView.This review traces the evolution of regioselective N‐functionalization strategies for pyrazoles, a key class of nitrogen heterocycles widely used in medicinal chemistry. Due to rapid tautomerism, N‐functionalization often lacks selectivity, leading to poor and unpredictable regioisomeric outcomes.
Lucas Popek +2 more
wiley +1 more source
, 2008 The alkylation at C-3 of the easily accessible (R)-2-[(S)-1,2-bis(benzyloxy)ethyl]-1-[(S)-1-phenylethyl]-2,3-dihydro-4(1H)-pyridone with different electrophiles took place with total trans diastereoselectivity to afford the corresponding (2R,3S)-2,3 ...
Ramón Badorrey +7 more
core +1 more source