Results 51 to 60 of about 5,613 (180)

Conversion Between 2‐ and 3‐Dimensional Halogen‐Bonded Networks Formed From a Single N‐Oxide/Iodoalkyne Building Block

open access: yesChemistry – A European Journal, Volume 32, Issue 25, 2 July 2026.
Open halogen‐bonded networks have been prepared from building blocks that incorporate both iodoalkyne halogen bond donors and a pyridine‐N‐oxide halogen bond acceptor. An initially‐formed 3D network containing dioxane in its channels undergoes an unprecedented transition to a 2D material when crystals are exposed to diethyl ether.
Jordan N. Smith   +4 more
wiley   +1 more source

Synthesis of New Aza-Heterocyclic Based on 2-Pyridone

open access: yesChemistry Proceedings
In this work, we present new methods of synthesis of different molecules including a 2-pyridone nucleus. First, we prepared a series of 1H-free 2-pyridones and N-alkyl 2-pyridones from ethyl cyanoacetate, aromatic aldehydes, various acetophenone ...
Ikram Baba-Ahmed   +4 more
doaj   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

open access: yesThe FEBS Journal, Volume 293, Issue 12, Page 3601-3620, June 2026.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil   +7 more
wiley   +1 more source

Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman   +2 more
wiley   +1 more source

One-pot Synthesis of 6-Aza-chromone Derivatives Through Cascade Carbonylation-Sonogashira-Cyclization

open access: yesScientific Reports, 2017
We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction.
Gang Cheng   +5 more
doaj   +1 more source

Reactions of 1,2,4‐Oxadiazole[4,5‐a]piridinium Salts with Alcohols: the Synthesis of Alkoxybutadienyl 1,2,4‐Oxadiazoles

open access: yesChemistryOpen, 2020
1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola   +2 more
doaj   +1 more source

Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

open access: yesMolecules, 2012
Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao   +9 more
doaj   +1 more source

Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones

open access: yesDrug Design, Development and Therapy, 2017
Galal Elgemeie,1 Farag Altalbawy,2,3 Mohammed Alfaidi,3 Rania Azab,2,4 Atef Hassan5 1Department of Chemistry, Faculty of Science, Helwan University, Helwan, 2National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt ...
Elgemeie G   +4 more
doaj  

Kristallstruktur eines 2-Dimethylamino-3,3-dimethyl-4(3H)-pyridons

open access: yesCHIMIA, 1982
3-Dimethylamino-2,2-dimethyl-2H-azirine (1) reacts with alkyl phenyl substituted cyclopropenones 2 in benzene at 130 °C to give a mixture of the two isomeric 4(3H)-pyridones 3 and 4, resulting from a nucleophilic attack at C(2) and C(1) of the ...
Jost H. Bieri   +2 more
doaj   +1 more source

3-Cyano-4,6-dimethyl-2-pyridone (Guareschi pyridone)

open access: yesActa Crystallographica Section E Structure Reports Online, 2004
In the crystal structure of the title compound, C8H8N2O, the mol­ecules form centrosymmetric dimers via N—H⋯O hydrogen bonds.
Victor B. Rybakov   +3 more
openaire   +1 more source

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