Results 61 to 70 of about 9,300 (167)

Natural Products from Marine Fungi—Still an Underrepresented Resource [PDF]

, 2016
Marine fungi represent a huge potential for new natural products and an increased number of new metabolites have become known over the past years, while much of the hidden potential still needs to be uncovered.
Imhoff, Johannes F.
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19F NMR as a Molecular Reporter: Labelling Strategies and Methods for Probing Biomolecular Motion and Exchange

Chemistry–Methods, Volume 6, Issue 2, February 2026.
This review summarizes the unique benefits 19F NMR spectroscopy has to offer for the study of biological systems. Particular focus is laid on the available strategies for incorporation of fluorinated probes into proteins and the latest applications of the ever‐expanding toolbox of fluorine NMR methodology to study structure and dynamics.
Charles Burridge, Björn M. Burmann
wiley   +1 more source

Synthesis and antimalarial potential of some novel quinoline-pyrazolopyridine derivatives [PDF]

, 2016
oai:eldorado.tu-dortmund.de:2003/35825A series of 1-(4-methylquinolin-2-yl)-4,6-diaryl-1H-pyrazolo[3,4-b]pyridin-3-amine derivatives was synthesized by the reaction of 3-cinnamoyl-4-hydroxy-6-methyl-2H-pyran-2-ones with 2-chloro-4,6 ...
Jain, Neelam, Jain, Sandeep, Kumar, Ajay, Saini, Deepika   +3 more
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Microbial metabolites in tumor epigenetic regulation

iMeta, Volume 5, Issue 1, February 2026.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang, Haoling Zhang, Yan Liao, Shuya Jiang, Haolong Zhang, Chenwei Huang, Zhijing Song, Rui Zhao, Ping Lu, Xiaohong Kang, Eryan Kong, Yalin Zhu, Wei Wang, Xuesong Liu, Yisheng Chen, Zhiwen Luo, Zhaoyu Li, Di Wang, Na Xing, Yadong Guo, Jingjing Zhang, Xiaojing Wang, Wenyi Wang, Mowaffaq Adam, Bakiah Shaharuddin, Muhamad Yusri Musa, Doblin Sandai, Chenglong Zhu, Aimin Jiang, Peng Luo, Zhijie Zhao, Zui Zou   +31 more
wiley   +1 more source

Systemic Toxicity of L‐Mimosine in Rabbits: A Non‐Rodent Model for Safety Assessment

Journal of Applied Toxicology, Volume 46, Issue 2, Page 639-651, February 2026.
ABSTRACT L‐mimosine is a non‐protein amino acid primarily found in the Mimosoideae subfamily, with high concentrations in Leucaena leucocephala and Mimosa pudica. These plants are widely used in both human and animal nutrition, as well as in phytotherapeutic applications. While the toxic effects of L‐mimosine have been extensively studied in ruminants,
S. M. Ferreira, H. Zapparoli, C. S. Mussi, P. C. Maiorka, A. F. C. Andrade, S. L. Górniak, A. T. Gotardo   +6 more
wiley   +1 more source

Ecofriendly Synthesis in Aqueous Medium: An Expeditious Approach to New N,N-Diethyl Amide Bearing Benzenemethanesulfonamides [PDF]

, 2013
An highly expeditious synthetic approach for the synthesis of benzenemethanesulfonamides (1a-k) and their new corresponding N,N-diethyl substituted amido moieties (2a-k) has been achieved in aqueous medium at room tem-perature. The reaction condition was
Ajani, O. O., Echeme, J. O., Familoni, O. B., Wu, F.   +3 more
core   +1 more source

Structural and molecular biology of a protein-polymerizing nanomachine for pilus biogenesis [PDF]

, 2017
Bacteria produce protein polymers on their surface called pili or fimbriae that serve either as attachment devices or as conduits for secreted substrates.
Waksman, Gabriel
core   +1 more source

Innovative solutions to sticky situations: Antiadhesive strategies for treating bacterial infections [PDF]

, 2016
Bacterial adherence to host tissue is an essential process in pathogenesis, necessary for invasion and colonization and often required for the efficient delivery of toxins and other bacterial effectors.
Aberg, Abgottspon, Allen, Allison, Alves, Aminov, Anderson, Andersson, Andersson, Andreini, Anthouard, Arnqvist, Aronson, Arrecubieta, Ashkar, Autar, Avorn, Bajolet-Laudinat, Barbosa-Cesnik, Barczak, Barnhart, Barnhart, Barocchi, Blanco, Bouckaert, Bouckaert, Boukerb, Boyle, Branderhorst, Breimer, Breimer, Briles, Britton, Brown, Buffie, Candela, Cecioni, Cecioni, Cegelski, Chabre, Chagnot, Chang, Chapman, Chemani, Chen, Chen, Chorell, Choudhury, Cioci, Clatworthy, Cole, Coppa, Cossart, Costerton, Cozens, Cusumano, Dam, Delnay, DePas, Dethlefsen, Diggle, Dodson, Donlan, Dramsi, Ebersbach, Eto, Evans, Fagon, Falugi, Ferreira, Findlow, Finlay, Finlay, Fischetti, Flores-Mireles, Foo, Ford, Foxman, Frankel, Furiga, Gao, Garcia-Medina, Gaudreau, Geibel, Gellatly, Ghosh, Giugliano, Glick, Goller, Gouin, Goyal, Greco, Greene, Griebling, Guiton, Guiton, Guiton, Guiton, Gustafsson, Guttilla, Haataja, Hakkarainen, Hammar, Hammer, Hammer, Hampton, Han, Han, Hansson, Hart, Haslam, Hauck, Hawley, Hentzer, Hernell, Hofmann, Hollenbeck, Horvath, Howell, Hung, Hung, Hur, Hur, Idanpaan-Heikkila, Isberg, Jacob-Dubuisson, Jay, Jiang, Jones, Jones, Joosten, Juliano, Kadam, Kadam, Kai-Larsen, Kang, Kang, Kauppi, Keeney, Kelly, Kierek-Pearson, Kim, Kim, Kim, Kisiela, Kleeb, Klein, Klein, Klein, Kline, Kontiokari, Konto-Ghiorghi, Korhonen, Kozel, Krachler, Krachler, Krachler, Kruger, Kummerfeldt, Langermann, Langermann, Lanne, Lanne, Larsson, Lebeaux, Lee, Lee, Lee, Lehner, Lewis, Li, Liu, Liukkonen, Lo, Loveless, Lund, Lyczak, Ma, Mack, Mamo, Mandlik, Manefield, Mapingire, Maresso, Maresso, Maresso, Marotte, Marraffini, Mayville, Mazmanian, Mazmanian, Menard, Migone, Migone, Miller, Mitchell, Morrow, Morvan, Munera, Murray, Mysore, Nallapareddy, Neeser, Nenninger, Nenninger, Newburg, Nicolle, Nielsen, Nielsen, Nielubowicz, Nishikawa, Nishikawa, Nishiyama, Nuccio, O'Toole, Ofek, Ofek, Oh, Oh, Oh, Ohlsson, Ohlsson, Okuda, Olsen, Oppong, Orndorff, Otsuka, Paganelli, Pak, Palumbi, Pang, Park, Parker, Patel, Perret, Pertici, Peychl, Phan, Piatek, Pieters, Pinkner, Prabu, Proft, Puorger, Pusztai, Raghunathan, Rapsinski, Rasko, Remaut, Remaut, Rivera, Roberts, Robinson, Rosen, Ruiz-Palacios, Saeki, Saldana, Salminen, Sauer, Sauer, Savar, Scharenberg, Schlager, Schneewind, Schroten, Schulte, Schwardt, Scott, Sekirov, Serruto, Sheth, Shu, Signoretto, Smith, Song, Staat, Stamm, Starkey, Steadman, Stromqvist, Su, Svensson, Thanassi, Therrien, Thomas, Tielker, Toivanen, Ton-That, Ton-That, Ton-That, Ton-That, Turgeon, Ubeda, Van Houdt, Vangay, Vengadesan, Volkan, Walsh, Wang, Wang, Wellens, Whittaker, Wilson, Wolinsky, Wu, Wu, Wurpel, Xiao, Yamaguti-Sasaki, Yamanaka, Yanagawa, Younson, Zhang, Zhang, Zinger-Yosovich   +314 more
core   +2 more sources

A Short Synthesis of (±)-3-Demethoxyerythratidinone by Ligand Controlled Selective Heck Cyclization of Equilibrating Enamines [PDF]

, 2017
A short, 5-step total synthesis of (±)-3-demethoxyerythratidinone from a simple pyrrole derivative is described. Features include the formation of gram quantities of a key tricylic aziridine from a challenging photochemical cascade reaction through the ...
Albini, Bach, Belleau, Blackham, Cassayre, Chikaoka, Chuang, Dean, Elliott, Gao, Gauthier, Heller, Ishibashi, Joo, Kirschbaum, Knowles, Kärkäs, Larionov, Le Anh Tuan, Lee, Luu, Martin, Maskill, Nicolaou, Onozaki, Padwa, Paladino, Parsons, Rigby, Rigby, Tolman, Trost, Tsuda, Tsuda, Wang, Wasserman, Xu, Zeni, Zhang, Zhang   +39 more
core   +2 more sources

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model. [PDF]

, 2013
The pyridine heterocycle continues to play a vital role in the development of human medicines. More than 100 currently marketed drugs contain this privileged unit, which remains highly sought after synthetically. We report an efficient means to access di-
Garg, Neil K, Goetz, Adam E
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