Results 61 to 70 of about 7,227 (222)

)‐pyridones

, 2008
The alkylation at C-3 of the easily accessible (R)-2-[(S)-1,2-bis(benzyloxy)ethyl]-1-[(S)-1-phenylethyl]-2,3-dihydro-4(1H)-pyridone with different electrophiles took place with total trans diastereoselectivity to afford the corresponding (2R,3S)-2,3 ...
Ramón Badorrey, Pablo Etayo, Etayo, Pablo, María D. Díaz‐de‐Villegas, José A. Gálvez, Díaz de Villegas, María D., Badorrey, Ramón, Gálvez, José A.   +7 more
core   +1 more source

Tautomerism of 4-Pyridones [PDF]

Bulletin of the Chemical Society of Japan, 1977
Abstract The tautomeric constants, Kt, of several 4-pyridones were determined by measurement of pKa values. For 2-substituted 5-methoxy-4-pyridones, the Kt values were correlated to the substituent constants σ, the equation logkt=2.98+2.93σm−6.18σo being obtained.
Hiromichi Besso, Kimiaki Imafuku, Hisashi Matsumura   +2 more
openaire   +1 more source

Conversion Between 2‐ and 3‐Dimensional Halogen‐Bonded Networks Formed From a Single N‐Oxide/Iodoalkyne Building Block

Chemistry – A European Journal, EarlyView.
Open halogen‐bonded networks have been prepared from building blocks that incorporate both iodoalkyne halogen bond donors and a pyridine‐N‐oxide halogen bond acceptor. An initially‐formed 3D network containing dioxane in its channels undergoes an unprecedented transition to a 2D material when crystals are exposed to diethyl ether.
Jordan N. Smith, Courtney Ennis, Huan V. Doan, Valeska P. Ting, Nicholas G. White   +4 more
wiley   +1 more source

Total Syntheses of Agelamadin F and (±)‐Tauroacidin A, Enabled by NaClO2‐Mediated Coupling Reactions of Oroidin and Amines

Chemistry – A European Journal, EarlyView.
Total syntheses of agelamadin F and (±)‐tauroacidin A were achieved by sodium chlorite (NaClO2)‐mediated oxidative C─N coupling. Nine C15–N–amino acid‐substituted oroidin derivatives were successfully prepared to demonstrate the applicability and versatility of this oxidative coupling reaction.
Ryosuke Hirozumi, Yuta Kudo, Yuko Cho, Mari Yotsu‐Yamashita   +3 more
wiley   +1 more source

K2S2O8-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones

, 2021
We herein present the synthesis of diversely functionalized pyrimidine fused thiazolino-2-pyridones via K2S2O8-mediated oxidative coupling of 6-amino-7-(aminomethyl)-thiazolino-2-pyridones with aldehydes.
Gharibyan, Anna, Gharibyan, Anna,, Tyagi, Mohit,, Bonde, Mari,, Tyagi, Mohit, Singh, Pardeep,, Bharate, Jaideep B.,, Ådén, Jörgen,, Ådén, Jörgen, Olofsson, Anders, Singh, Pardeep, Adolfsson, Dan E., Olofsson, Anders,, Vielfort, Katarina, Adolfsson, Dan E.,, Almqvist, Fredrik, Jayaweera, Sanduni Wasana,, Bharate, Jaideep B., Bergström, Sven, Jayaweera, Sanduni Wasana, Bonde, Mari, Almqvist, Fredrik,, Vielfort, Katarina,, Bergström, Sven,   +23 more
core   +1 more source

Interfacial Charge‐Transfer Enhancement via High‐Entropy Alloy Regulated MXene Heterostructures for Asymmetric Supercapacitor Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A novel core‐shell HEA@MXene composite was synthesized to enhance supercapacitor electrochemistry. DFT simulations reveal the role of HEA doping in regulating the MXene interface. The HEA@MXene composite exhibits a high specific capacitance of 872 F g−1 at 1 A g−1 with remarkable stability in 1 M KOH.
Fenhong Song, Ruibo Zhang, Wanlong Chu, Zengqiang Tan, Long Ma, Jing Fan, Gang Wang, Qi Qi, Yang Cao   +8 more
wiley   +1 more source

Binuclear Copper‐Dependent Oxidative Enzymes Involved in Fungal Natural Product Modifications

Journal of the Chinese Chemical Society, EarlyView.
This article summarizes recent biochemical characterizations of a new enzyme family named by the authors as binuclear copper‐dependent oxidative enzymes (BiNCOs). Found in fungal natural product biosynthesis, BiNCOs catalyze diverse CH functionalization reactions, including C(sp3)H halogenation, C(sp3)H hydroxylation, C(sp3)O macrocyclization, and ...
Chen‐Yu Chiang, Masao Ohashi, Yi Tang
wiley   +1 more source

Comparative evaluation of noncanonical amino acids as site‐specific NMR probes for the complex of E. coli SSB with single‐stranded DNA without isotope labelling

The FEBS Journal, EarlyView.
Genetic encoding of noncanonical amino acids (ncAA) enables their site‐specific installation in proteins. This work compares the nuclear magnetic resonance (NMR) performance of different ncAAs in a large protein−DNA complex (~ 100 kDa) without isotope labelling. The ncAAs deliver readily detectable NMR signals in the complex between E.
Sreelakshmi Mekkattu Tharayil, Haocheng Qianzhu, Elwy H. Abdelkader, Adarshi P. Welegedara, Josemon George, Christoph Nitsche, Thomas Huber, Gottfried Otting   +7 more
wiley   +1 more source

General Method for the Preparation of Substituted 2-Amino-4H,5H-pyrano[4,3-b]pyran-5-ones and 2-Amino-4H-pyrano[3,2-c]pyridine-5-ones

Molecules, 2000
Reaction of 4-hydroxy-6-methyl-2-pyrone (1a) as well as 4-hydroxy-6-methyl-2(1H)-pyridones (1b-d) with arylmethylene malononitriles or arylmethylene methyl cyanoacetates (2a-h) leads to the formation of the very stable 5,6-fused bicyclic 2-amino-4Hpyran ...
Dieter Heber, Ivo C. Ivanov, Edmont V. Stoyanov   +2 more
doaj   +1 more source

Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products

Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman, Mathieu Frenette, Sylvain Canesi   +2 more
wiley   +1 more source