Results 81 to 90 of about 7,227 (222)
Streamlining the Synthesis of Pyridones through Oxidative Amination
Herein we report the development of an oxidative amination process for the streamlined synthesis of pyridones from cyclopentenones. Cyclopentenone building blocks can undergo in situ silyl enol ether formation, followed by the introduction of a nitrogen ...
Florian, Ruepp +5 more
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Regioselective Halogenations and Subsequent Suzuki−Miyaura Coupling onto Bicyclic 2-Pyridones
, 2016 A selective synthesis of 6-bromo-8-iodo dihydro thiazolo ring-fused 2-pyridones is described. These halogenated 2-pyridones are selectively arylated by sequential Suzuki−Miyaura couplings.
Fredrik Almqvist (698391) +1 more
core +1 more source
ChemistryOpen, Volume 15, Issue 4, April 2026.Palladium is a simple and versatile redox‐active metal that plays a crucial role in the oxidation reactions for organic synthesis and production of pharmaceutical intermediates. Notably, there has been significant progress with Lewis acids (LAs), which are non‐redox metal ions promoting Pd(II)‐catalyzed oxidation via C—H and C—C bond activation.
Ahmed M. Senan +3 more
wiley +1 more source
Synthesis of New Potentially Bioactive Bicyclic 2-Pyridones
Molecules, 2005 Three convenient methods of reduction of the nitro group of 5-nitroimidazoles and 5-nitrothiazole that bear a diethylmethylene malonate group in an ortho-like position with respect to the nitro group and cyclization of the resulting amino derivatives are
Patrice Vanelle +3 more
doaj +1 more source
Asymmetric Negishi and Kumada Couplings
Advanced Synthesis &Catalysis, Volume 368, Issue 5, 3 March 2026.This review summarizes asymmetric Negishi and Kumada cross‐coupling reactions from the 1980s through 2025. It examines enantioselective and enantiospecific transformations catalyzed by nickel, palladium, and cobalt complexes , highlighting ligand design, mechanistic insights, and applications in constructing complex chiral molecules and natural ...
Rui‐Heng Wang, Aishun Ding, Ramon Rios
wiley +1 more source
Rhodium-Catalyzed C6-Selective C–H Borylation of 2‑Pyridones
, 2016 A pyridine-directed, rhodium-catalyzed C6-selective C–H borylation of 2-pyridones with bis(pinacolato)diboron (pinB–Bpin) has been developed. The reaction proceeds smoothly under relatively mild conditions, and the corresponding C6-borylated 2 ...
Wataru Miura (715942) +2 more
core +1 more source
, 2020 2,3-Dihydro-4-pyridone skeleton is an important building block in organic synthesis because it features several reaction sites with nucleophilic or electrophilic properties.
Stojanović, Milovan +2 more
core +1 more source
Dinuclear Rhodium(I)–N‐Heterocyclic Carbene Complexes as Alkyne Hydropyridonation Catalysts
European Journal of Inorganic Chemistry, Volume 29, Issue 7, 2 March 2026.Catalyst Improvement by NHC tuning: A series of new RhI–NHC dinuclear complexes has been revealed as efficient alkyne hydropyridonation catalysts. 333053IMes complex displays the highest reactivity of the series, suggesting that a moderate steric demand combined with balanced σ‐donation facilitates precatalyst activation and substrate exchange.
Belinda Español‐Sánchez +7 more
wiley +1 more source
, 2017 In this thesis, a library of novel unsymmetrical tridentate NNO- and ONO'-type ligands are synthesized and complexed with sources of palladium(II) with a view to exploring the reactivity of the so-formed pincer complexes and their role in CH-halogenation.
Amandeep Singh (3511400)
core +1 more source
Phenacylation of 6-Methyl-Beta-Nitropyridin-2-Ones and Further Heterocyclization of Products
Molecules, 2020 Reaction between the derivatives of 6-methyl-beta-nitropyridin-2-one and phenacyl bromides was studied, and the yields observed were extremely low. The pyridones were converted via chloropyridines to methoxyderivatives, which were N-phenacylated.
Eugene V. Babaev, Victor B. Rybakov
doaj +1 more source