Results 91 to 100 of about 7,788 (207)

Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones

, 2019
We report the synthesis of 6-arylthio-substituted-N-alkenyl 2-pyridones by ring opening of bicyclic thiazolino-2-pyridones with arynes. Varied functionalization was used to investigate scope and substituent influences on reactivity.
Adolfsson, Dan E.,, Almqvist, Fredrik, Singh, Pardeep,, Sauer, Uwe H.,, Cairns, Andrew G., Ådén, Jörgen,, Ådén, Jörgen, Cairns, Andrew G.,, Singh, Pardeep, Almqvist, Fredrik,, Adolfsson, Dan E., Sauer, Uwe H.   +11 more
core   +1 more source

Reaction of acyclic enaminones with methoxymethylene meldrum's acid: synthetic and structural implications

Journal of the Brazilian Chemical Society, 2003
The reaction of acyclic enaminones with methoxymethylene Meldrum's acid afforded N-adduct and/or C-adduct of enaminones in moderate to good yields. The regiochemistry of this reaction depends on the N-amino substituent of the enaminone. The C-adduct is a
Cunha Silvio, Silva Viviane C. da, Napolitano Hamilton B., Lariucci Carlito, Vencato Ivo   +4 more
doaj  

Synthesis of Densely Functionalized N‑Alkenyl 2‑Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2‑Pyridones

, 2019
We report the synthesis of 6-arylthio-substituted-N-alkenyl 2-pyridones by ring opening of bicyclic thiazolino-2-pyridones with arynes. Varied functionalization was used to investigate scope and substituent influences on reactivity.
Pardeep Singh (294895), Jörgen Ådén (1820980), Dan E. Adolfsson (6483089), Andrew G. Cairns (1282671), Fredrik Almqvist (698391), Uwe H. Sauer (7255691)   +5 more
core   +1 more source

Energy-Transfer Catalysis Enables the Birch-Type Reduction of 2-Pyridones. [PDF]

Angew Chem Int Ed Engl
Hartmann P, Liljenberg S, Domack J, Hölter N, Daniliuc C, Glorius F.   +5 more
europepmc   +1 more source

Genome mining guided identification of new furo[3,2-c]pyridones phaeopyridones A-C from the endophytic fungus Phaeobotryon negundinis 12020. [PDF]

Nat Prod Bioprospect
Ye K, Shi J, Wu H, Wang S, Lin Z, Sun J, Chen Y, Wang B, Wang R, Jiang C, Jiang Y, Hsiang T, Zhu B, Zhang L, Liu X, Zhu G.   +15 more
europepmc   +1 more source

Hydroamination of Dehydroalanine With Deuterium Incorporation to Access Unnatural 2- and 4-Pyridonyl α-Amino Acids: Evaluation of Their Antibacterial, Antifungal, and Immunomodulatory Activities. [PDF]

ChemMedChem
Udayakumar SB, Kumar P, Pranathi KS, Prajapati A, Misra S, Bonam SR, Nayani K.   +6 more
europepmc   +1 more source

Competitive cyclization of ethyl trifluoroacetoacetate and methyl ketones with 1,3-diamino-2-propanol into hydrogenated oxazolo- and pyrimido-condensed pyridones. [PDF]

Beilstein J Org Chem
Kushch SO, Goryaeva MV, Burgart YV, Ezhikova MA, Kodess MI, Slepukhin PA, Volobueva AS, Zarubaev VV, Saloutin VI.   +8 more
europepmc   +1 more source

Ultrasound for the determination of appropriate needle length for intragluteal injection of long-acting rilpivirine-cabotegravir. [PDF]

HIV Med
Gueuning C, Brizmohun M, Dauby N, Martin C.   +3 more
europepmc   +1 more source

Formal [1 + 2 + 3] Annulation of Anilines and CF₃‑Containing Ynones via 6π-Electrocyclization. [PDF]

Precis Chem
Feng L, Ni SF, Lai Y, Zhang X, Lu ZX, Xiong HY, Zhang G, Wang T.   +7 more
europepmc   +1 more source

An Observational Study of the Effect of Concomitant Levetiracetam on Apixaban Concentrations in a Hospital Cohort. [PDF]

Clin Transl Sci
Riley C, Lam K, Micale C, Thomson L, Stickle DF, Kraft WK.   +5 more
europepmc   +1 more source