Results 91 to 100 of about 7,227 (222)

Gold(I)-Catalyzed Intramolecular Hydroamination of Unactivated Terminal and Internal Alkenes with 2‑Pyridones

, 2017
The cationic gold phosphine complex [(P1)­Au­(NCMe)]+SbF6– [P1 = P­(t-Bu)2o-biphenyl; 2] catalyzes the intramolecular hydroamination of 6-alkenyl-2-pyridones to form 1,6-carboannulated 2-pyridones in high yield.
Jacob C. Timmerman (3119301), Sébastien Laulhé (2032621), Ross A. Widenhoefer (1375383)   +2 more
core   +1 more source

Reactions of 1,2,4‐Oxadiazole[4,5‐a]piridinium Salts with Alcohols: the Synthesis of Alkoxybutadienyl 1,2,4‐Oxadiazoles

ChemistryOpen, 2020
1,2,4‐Oxadiazole[4,5‐a]piridinium salts add alcohols and alkoxides to undergo electrocyclic ring opening affording alkoxybutadienyl 1,2,4‐oxadiazole derivatives.
Dr. Mattia Moiola, Dr. Marco Leusciatti, Prof. Dr. Paolo Quadrelli   +2 more
doaj   +1 more source

One-pot Synthesis of 6-Aza-chromone Derivatives Through Cascade Carbonylation-Sonogashira-Cyclization

Scientific Reports, 2017
We developed an efficient synthesis of aza-chromones from 3-iodo-4-(1H)-pyridones and terminal acetylenes via a cascade carbonylation-Sonogashira-cyclization reaction.
Gang Cheng, Yingbei Qi, Xiaoqian Zhou, Rong Sheng, Yong-Zhou Hu, Youhong Hu   +5 more
doaj   +1 more source

Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones

, 2019
We report the synthesis of 6-arylthio-substituted-N-alkenyl 2-pyridones by ring opening of bicyclic thiazolino-2-pyridones with arynes. Varied functionalization was used to investigate scope and substituent influences on reactivity.
Adolfsson, Dan E.,, Almqvist, Fredrik, Singh, Pardeep,, Sauer, Uwe H.,, Cairns, Andrew G., Ådén, Jörgen,, Ådén, Jörgen, Cairns, Andrew G.,, Singh, Pardeep, Almqvist, Fredrik,, Adolfsson, Dan E., Sauer, Uwe H.   +11 more
core   +1 more source

Synthesis of Densely Functionalized N‑Alkenyl 2‑Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2‑Pyridones

, 2019
We report the synthesis of 6-arylthio-substituted-N-alkenyl 2-pyridones by ring opening of bicyclic thiazolino-2-pyridones with arynes. Varied functionalization was used to investigate scope and substituent influences on reactivity.
Pardeep Singh (294895), Jörgen Ådén (1820980), Dan E. Adolfsson (6483089), Andrew G. Cairns (1282671), Fredrik Almqvist (698391), Uwe H. Sauer (7255691)   +5 more
core   +1 more source

Synthesis of 4-Pyridone-3-sulfate and an improved synthesis of 3-Hydroxy-4-Pyridone [PDF]

Chemistry Central Journal, 2009
An improved synthesis of 3-hydroxy-4-pyridone via an Elbs oxidation of 4-pyridone and isolation of 4-pyridone-3-sulfate is described.
openaire   +3 more sources

Synthesis, characterization, and antimicrobial evaluation of novel 5-benzoyl-N-substituted amino- and 5-benzoyl-N-sulfonylamino-4-alkylsulfanyl-2-pyridones

Drug Design, Development and Therapy, 2017
Galal Elgemeie,1 Farag Altalbawy,2,3 Mohammed Alfaidi,3 Rania Azab,2,4 Atef Hassan5 1Department of Chemistry, Faculty of Science, Helwan University, Helwan, 2National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza, Egypt ...
Elgemeie G, Altalbawy F, Alfaidi M, Azab R, Hassan A   +4 more
doaj  

Design, Synthesis and Antifibrotic Activities of Carbohydrate- Modified 1-(Substituted aryl)-5-trifluoromethyl-2(1H) Pyridones

Molecules, 2012
Pirfenidone, a pyridone compound, is an effective and novel antifibrotic agent. In this article, we describe the design, synthesis and activity evaluation of novel antifibrotic agents, 1-(substituted aryl)-5-trifluoromethyl-2(1H) pyridones modified with ...
Lijian Tao, Zhongjun Li, Renna Luo, Gaoyun Hu, Qi Hou, Zhiqi Lao, Lingling Xuan, Jinye Bai, Xiangbao Meng, Qinghua Lou   +9 more
doaj   +1 more source

Iridium-Catalyzed Site-Selective C–H Borylation of 2-Pyridones

, 2017
An iridium-catalyzed site-selective C–H borylation of 2-pyridones has been developed. The site selectivity is predominantly controlled by steric factors, and we can access C4, C5, and C6 C–H on the 2-pyridone ring by the judicious choice of ligand and ...
Masahiro Miura, Koji Hirano, Wataru Miura   +2 more
core   +1 more source

Kristallstruktur eines 2-Dimethylamino-3,3-dimethyl-4(3H)-pyridons

CHIMIA, 1982
3-Dimethylamino-2,2-dimethyl-2H-azirine (1) reacts with alkyl phenyl substituted cyclopropenones 2 in benzene at 130 °C to give a mixture of the two isomeric 4(3H)-pyridones 3 and 4, resulting from a nucleophilic attack at C(2) and C(1) of the ...
Jost H. Bieri, Roland Prewo, Heinz Heimgartner   +2 more
doaj   +1 more source