Results 71 to 80 of about 7,227 (222)

Surface‐Bound Superoxide Radical‐Mediated Photo‐Fenton Mineralization of Ciprofloxacin on Fe‐Sillenite Nanosheets

open access: yesAdvanced Science, Volume 13, Issue 29, 22 May 2026.
This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu   +9 more
wiley   +1 more source

Defect‐Regulated Electronic and Lattice Evolution in Na4VMn(PO4)3 Toward High‐Performance Sodium Storage

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT NASICON‐type Na4VMn(PO4)3 (NVMP) is a promising high‐capacity cathode for sodium‐ion batteries, yet its practical deployment is hindered by Mn3+‐driven lattice distortion, persistent oxygen vacancy defects, and sluggish Na+ transport, collectively resulting in accelerated performance degradation.
Deyi Zhang   +10 more
wiley   +1 more source

Synthesis and Properties of Substituted 1-(2-Benzothiazolyl)-2-pyridones

open access: yes, 1995
The studied 1-(2-benzothiazolyl)-2-pyridones Va-Vf were prepared from N-(2-benzothiazolyl)cyanoacetamide (II) which on reaction with 4-substituted benzaldehydes afforded 3-aryl-N-(2-benzothiazolyl)-2-cyano-2-propenamides IVa-IVg.
Dušan Ilavský   +5 more
core   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2219-2235, May 2026.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind   +6 more
wiley   +1 more source

New functionalisation chemistry of 2- and 4-pyridones and related heterocycles [PDF]

open access: yes, 2016
New methodology for the synthesis of several 4H-pyrido[1,2-a]pyrimidin-4-ones has been developed from commercially available 2-aminopyridines and β-oxo esters catalysed by Montmorillonite under solvent-free conditions in good yields. This methodology was
Beatriz Fernandez (5781758)
core   +1 more source

Safety of beta‐nicotinamide mononucleotide (β‐NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC

open access: yesEFSA Journal, Volume 24, Issue 5, May 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on beta‐nicotinamide mononucleotide (β‐NMN) as a novel food (NF) pursuant to Regulation (EU) 2015/2283, including an evaluation of the safety of its use in food supplements as a source of niacin ...
EFSA Panel on Nutrition   +28 more
wiley   +1 more source

Synthesis of New Aza-Heterocyclic Based on 2-Pyridone

open access: yesChemistry Proceedings
In this work, we present new methods of synthesis of different molecules including a 2-pyridone nucleus. First, we prepared a series of 1H-free 2-pyridones and N-alkyl 2-pyridones from ethyl cyanoacetate, aromatic aldehydes, various acetophenone ...
Ikram Baba-Ahmed   +4 more
doaj   +1 more source

A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones

open access: yesMolecules, 2019
Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied.
Federica Arioli   +5 more
doaj   +1 more source

Regioselective Halogenations and Subsequent Suzuki-Miyaura Coupling onto Bicyclic 2-Pyridones

open access: yes, 2010
A selective synthesis of 6-bromo-8-iodo dihydro thiazolo ring-fused 2-pyridones is described. These halogenated 2-pyridones are selectively arylated by sequential Suzuki-Miyaura couplings.
Bengtsson, Christoffer,   +1 more
core   +1 more source

Copper‐ and Silver‐Catalyzed Reactions of Active Methylene Isocyanides: Facile Access to Highly Substituted Five‐ and Six‐Membered Heterocycles

open access: yesChemistry – A European Journal, Volume 32, Issue 13, 1 April 2026.
This review summarizes recent advances in copper‐ and silver‐catalyzed reactions of active methylene isocyanides for the synthesis of highly substituted five‐ and six‐membered heterocycles. Emphasis is placed on [3+n] cycloadditions, annulations, and asymmetric strategies, highlighting current limitations and future opportunities in heterocycle ...
Jimil George, Kyungsoo Oh
wiley   +1 more source

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