Results 101 to 110 of about 26,777 (227)

Graded Levels of Dietary Valine in Protein‐Restricted Diets: Effects on Reproductive Performance and Tissue Morphology in Laying Japanese Quail

open access: yesVeterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Dietary supplementation of 0.95% valine in protein‐restricted diets optimizes reproductive performance, egg quality, and ovarian follicular development in laying Japanese quail. Higher levels do not provide additional benefits and may increase hepatic metabolic demand, highlighting the importance of precise amino acid formulation in low‐protein feeding
Morteza Pashaei Jalal   +3 more
wiley   +1 more source

Pharmaceutical policy and off‐label prescribing in pregnancy: A population‐based historical cohort study analyzing inequality in access to antiemetics within Australia's Pharmaceutical Benefits Scheme

open access: yesActa Obstetricia et Gynecologica Scandinavica, Volume 105, Issue 9, Page 1789-1799, September 2026.
Public spending on antiemetics among pregnant women in Australia is concentrated in socioeconomically disadvantaged women. However, public expenditure is also driven by off‐label ondansetron use (i.e., use outside regulatory‐approved indications), highlighting a misalignment between pharmaceutical policy, public expenditure patterns, and pregnant women'
Hannah Jackson   +4 more
wiley   +1 more source

Chemoenzymatic Synthesis of Chiral Piperidines Using the Immobilized Transaminase ATA‐117 in Continuous Flow Reactors

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 15, 1 August 2026.
A robust continuous flow chemoenzymatic process was developed for the stereoselective synthesis of cis‐(2R,6R)‐2,6‐disubstituted piperidines, including the natural alkaloid (–)‐pinidinone. The asymmetric transamination of α,β‐unsaturated ketones was catalyzed by immobilized ATA‐117, followed by spontaneous aza‐Michael cyclization, providing the desired
Sara Vicinanza   +11 more
wiley   +1 more source

Long‐Term Effects of a Dietary Humic Substance–Butyrate Blend, and Yeast Cell Wall on Growth Performance, Immune Status and Gut Microbiota of Juvenile Channel Catfish Ictalurus punctatus

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT This study evaluated the long‐term effects of a dietary humic substance and butyrate blend (HSB) alone or with yeast cell wall (Beta‐MOS) in channel catfish. Around 1440 fish (31.31 ± 0.24 g) were distributed among 12 outdoor tanks in a pond‐supplied flow‐through design. Four dietary treatments were evaluated in triplicate: Diets containing no
Abdulmalik A. Oladipupo   +5 more
wiley   +1 more source

Effect of Late Second to Early Third Trimester of Pregnancy on the Activity of Renal Organic Anion Transporters (OAT1 and OAT3): A Biomarker Study

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 465-474, August 2026.
Pregnant individuals take drugs throughout pregnancy and many of these drugs (e.g., antivirals, antibiotics) are eliminated by renal organic anion transporters (OAT) 1 and OAT3. In vivo studies with OAT1/3 substrate drugs suggest that pregnancy increases renal OAT1/3 activities by 1.5‐ to 1.8‐fold.
Aarzoo Thakur   +4 more
wiley   +1 more source

Uncovering Coenzyme Q10‐Related Genetic Determinants of Statin‐Associated Muscle Symptoms: Evidence from the UK Biobank and the All of Us Research Program

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 475-483, August 2026.
Statin‐associated muscle symptoms (SAMS) are frequent adverse effects of statin therapy and have been hypothesized to result from impaired coenzyme Q10 (CoQ10) biosynthesis. Although genetic determinants of CoQ10 levels have been reported, genome‐wide association studies (GWASs) conducted specifically in statin users are lacking. Moreover, direct CoQ10
Da Hoon Lee   +6 more
wiley   +1 more source

Stage‐Specific Metabolic and Proteomic Dynamics Underlying Ripening and Quality Formation in Tropical Evergreen Pomegranate

open access: yeseFood, Volume 7, Issue 4, August 2026.
Integrated multi‐omics reveals that pomegranate ripening between 90 and 130 days drives optimal sugar‐acid balance and pigmentation via coordinated regulation of phenylpropanoid, flavonoid, and carbohydrate metabolism pathways. ABSTRACT Pomegranate fruit development involves coordinated physiological, metabolic, and proteomic changes shaping coloration
Yawen Zhang   +6 more
wiley   +1 more source

Delay in Diagnosis of Classical Homocystinuria. [PDF]

open access: yesJIMD Rep
Wanninayake S   +5 more
europepmc   +1 more source

Genetic landscape of patients with atypical absence status epilepticus: A systematic review

open access: yesEpilepsia Open, Volume 11, Issue 4, Page 1111-1125, August 2026.
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu   +2 more
wiley   +1 more source

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