Vitamin B6 and arteriosclerosis. [PDF]
In 1949, Rinehart and Greenberg reported that marked arteriosclerosis occurs in vitamin-B6-deficient monkeys. The present study investigates the relationship between vitamin B6 and arteriosclerosis and summarizes the results. I found that thrombogenesis, disorder of collagen metabolism and production of free radicals may be the processes that cause ...
KUZUYA, FUMIO
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Vitamin B6 and Cardiovascular Disease
While overt vitamin B6 deficiency is not a frequent finding nowadays in medical practice, evidence suggests that insufficiency of this vitamin is rather widespread in a quite large portion of the population such as the elderly or in not unusual conditions such as that of alcohol addiction.
FRISO, Simonetta +3 more
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Expert Consensus on Vitamin B6 Therapeutic Use for Patients: Guidance on Safe Dosage, Duration and Clinical Management. [PDF]
Natalie Schellack,1 Kitiyot Yotsombut,2 Arman Sabet,3 Jalal Nafach,4 Fu Liong Hiew,5 Kongkiat Kulkantrakorn6 1Department of Pharmacology, University of Pretoria, Pretoria, Gauteng, South Africa; 2Department of Pharmacy Practice, Chulalongkorn University,
Schellack N +5 more
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Vitamin B6 in Health and Disease [PDF]
Vitamin B6 is a fascinating molecule involved in the vast majority of changes in the human body because it is a coenzyme involved in over 150 biochemical reactions. It is active in the metabolism of carbohydrates, lipids, amino acids, and nucleic acids, and participates in cellular signaling.
Stach, Kamilla +2 more
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Cognitive and mood effects in healthy children during 12 weeks' supplementation with multi-vitamin/minerals [PDF]
Adequate levels of vitamins and minerals are essential for optimal neural functioning. A high proportion of individuals, including children, suffer from deficiencies in one or more vitamins or minerals.
Kennedy, David O +26 more
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Reduction in dietary vitamin B6 intakes is associated with increased relative risk of diseases such as cancer, atherosclerosis, and cognitive dysfunction.
Welham, Simon +2 more
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Vitamin B6-Dependent and Vitamin B6-Responsive Disorders
The importance of vitamin B6 is evident by its role as the most abundant cofactor in human metabolism. A total of six different B6 vitamers follow a complex pathway of absorption and transformation into the final active cofactor, pyridoxal 5′-phosphate (PLP), which catalyses over 100 reactions, mainly in amino acid and neurotransmitter metabolism. Over
Plecko, Barbara, Struys, Eduard A.
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Vitamin B-12 deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N. +37 more
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A randomised controlled trial investigating the effect of vitamin B12 supplementation on neurological function in healthy older people: the Older People and Enhanced Neurological function (OPEN) study protocol [ISRCTN54195799]. [PDF]
BACKGROUND: Vitamin B12 deficiency is common in older people and the prevalence increases with age. Vitamin B12 deficiency may present as macrocytic anaemia, subacute combined degeneration of the spinal cord, or as neuropathy, but is often asymptomatic ...
Allen, Elizabeth +32 more
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Vitamin B6 and selenium supplementation induce contrasting effects in the transsulfuration pathway of juvenile rainbow trout (Oncorhynchus mykiss) with interactive effects in stressed fish [PDF]
This study aimed to investigate the interactive effects between selenium and vitamin B6 supplementation in the transsulfuration pathway and glutathione metabolism of juvenile rainbow trout (Oncorhynchus mykiss) and in response to oxidative stress.
Surget, Anne +8 more
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