Results 21 to 30 of about 51,225 (273)

Assessing the genetic association between vitamin B6 metabolism and genetic generalized epilepsy

Molecular Genetics and Metabolism Reports, 2019
Altered vitamin B6 metabolism due to pathogenic variants in the gene PNPO causes early onset epileptic encephalopathy, which can be treated with high doses of vitamin B6.
Remi Stevelink, Faith Pangilinan, Floor E. Jansen, Kees P.J. Braun, Anne M. Molloy, Lawrence C. Brody, Bobby P.C. Koeleman   +6 more
doaj   +1 more source

Enhancement of vitamin B6 levels in rice expressing Arabidopsis vitamin B6 biosynthesis de novo genes [PDF]

, 2019
Vitamin B6 (pyridoxine) is vital for key metabolic reactions and reported to have antioxidant properties in planta. Therefore, enhancement of vitamin B6 content has been hypothesized to be a route to improve resistance to biotic and abiotic stresses ...
Mangel, Nathalie, Li, Kuan-Te, 25433, 25435, 25434, 25437, 25436, Szurek, Boris, 25439, Wu, Ting-Ying, 25438, Fernie, Alisdair R., Fitzpatrick, Teresa B., Gruissem, Wilhelm, 25440, Tohge, Takayuki, 25442, 25441, Fudge, Jared B., Vanderschuren, Herve   +19 more
core   +3 more sources

Strategies for vitamin B6 biofortification of plants: A dual role as a micronutrient and a stress protectant

Frontiers in Plant Science, 2013
Vitamin B6 has an essential role in cells as a cofactor for several metabolic enzymes. It has also been shown to function as a potent antioxidant molecule.
Hervé eVanderschuren, Svetlana eBoycheva, Kuan-Te eLi, Nicolas eSzydlowski, Wilhelm eGruissem, Teresa Bridget Fitzpatrick   +5 more
doaj   +1 more source

Vitamin B-12 deficiency stimulates osteoclastogenesis via increased homocysteine and methylmalonic acid [PDF]

, 2009
The risk of nutrient deficiencies increases with age in our modern Western society, and vitamin B(12) deficiency is especially prevalent in the elderly and causes increased homocysteine (Hcy) and methylmalonic acid (MMA) levels.
Bravenboer, N., Vaes, Bart L T, Vaes, B.L.T., Everts, V., Wilma T. Steegenga, Bravenboer, Nathalie, Steegenga, W.T., Lute, Carolien, Carolien Lute, de Groot, L.C.P.G.M., Müller, M.R., Henk J. Blom, de Groot, C.P.G.M., Muller, M., Dhonukshe-Rutten, R.A.M., de Groot, Lisette C P G M, Dhonukshe-Rutten, R.A., Bart L. T. Vaes, Teun J. de Vries, Blom, Henk J, Nathalie Bravenboer, Groot, L.C.P.G.M. de, de Vries, Teun J, Müller, Michael, Everts, Vincent, Rosalie A. Dhonukshe-Rutten, Michael Müller, de Vries, T.J., Lisette C. P. G. M. de Groot, Dhonukshe-Rutten, Rosalie A, Steegenga, Wilma T, Groot, C.P.G.M., de, Lute, C., Vries, T. J., Blom, H.J., Everts, V, Vries, T.J., de, Vincent Everts   +37 more
core   +1 more source

Efficacy of Supplementation with B Vitamins for Stroke Prevention: A Network Meta-Analysis of Randomized Controlled Trials.

PLoS ONE, 2015
BackgroundSupplementation with B vitamins for stroke prevention has been evaluated over the years, but which combination of B vitamins is optimal for stroke prevention is unclear.
Hongli Dong, Fuhua Pi, Zan Ding, Wei Chen, Shaojie Pang, Wenya Dong, Qingying Zhang   +6 more
doaj   +1 more source

Role of vitamin B6 status on antioxidant defenses, glutathione, and related enzyme activities in mice with homocysteine-induced oxidative stress

Food & Nutrition Research, 2015
Background: Vitamin B6 may directly or indirectly play a role in oxidative stress and the antioxidant defense system. Objective: The purpose of this study was to examine the associations of vitamin B6 status with cysteine, glutathione, and its related ...
Cheng-Chin Hsu, Chien-Hsiang Cheng, Chin-Lin Hsu, Wan-Ju Lee, Shih-Chien Huang, Yi-Chia Huang   +5 more
doaj   +1 more source

Effect of Pyridoxine on Prostaglandin Plasma Level for Primary Dysmenorrheal Treatment

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective : To determine the effect of vitamin B6 (pyridoxine) the levels of prostaglandins and intensity of pain in primary dysmenorrheal. Methods : The levels of prostaglandin (PGF2α) in plasma measured by ELISA and pain intensity by verbal rating ...
Ervan J Randabunga, Efendi Lukas, Josephine L Tumedia, St. Maisuri T. Chalid   +3 more
doaj   +1 more source

Vitamin B6: a scoping review for Nordic Nutrition Recommendations 2023

Food & Nutrition Research, 2023
Pyridoxal 5´-phosphate (PLP) is the main form of vitamin B6 in animal tissue and functions as a coenzyme for more than 160 different enzymatic reactions in the metabolism of amino acids, carbohydrates, lipids, and neurotransmitters.
Anne-Lise Bjørke-Monsen, Per Magne Ueland   +1 more
doaj   +1 more source

Vitamin B6 for cognition [PDF]

, 2003
Background Micronutrient status can affect cognitive function at all ages. Vitamin deficiencies could influence memory function and might contribute to age-associated cognitive impairment and dementia.
Evans, John, Evans, JG, Malouf, Reem, Malouf, RM   +3 more
core   +2 more sources

A randomised controlled trial investigating the effect of vitamin B12 supplementation on neurological function in healthy older people: the Older People and Enhanced Neurological function (OPEN) study protocol [ISRCTN54195799]. [PDF]

, 2011
BACKGROUND: Vitamin B12 deficiency is common in older people and the prevalence increases with age. Vitamin B12 deficiency may present as macrocytic anaemia, subacute combined degeneration of the spinal cord, or as neuropathy, but is often asymptomatic ...
Allen, Elizabeth, Kerry Mills, Whyte, K, Fletcher, Astrid E, Elbourne, Diana, Richards, Marcus, Ken Whyte, Mills, Kerry, Robert Clarke, Richards, M, Letley, Louise, Dangour, Alan D, Elbourne, D, Mills, K, Ricardo Uauy, Whyte, Ken, Louise Letley, Dangour, AD, Fletcher, AE, Diana Elbourne, Fasey, Nicky, Uauy, Ricardo, Alan D Dangour, Uauy, R, Astrid E Fletcher, Marcus Richards, Clarke, Robert, Clarke, R, Nicky Fasey, Elizabeth Allen, Fasey, N, Allen, E, Letley, L   +32 more
core   +1 more source