Pyridoxine Deficiency Exacerbates Neuronal Damage after Ischemia by Increasing Oxidative Stress and Reduces Proliferating Cells and Neuroblasts in the Gerbil Hippocampus. [PDF]
Int J Mol Sci, 2020 Jung HY +12 more
europepmc +3 more sources
Genotypic Spectrum in a Cohort of Sri Lankan Patients With Homocystinuria [PDF]
JIMD ReportsHomocystinuria due to cystathionine beta‐synthase (CBS) deficiency is a rare metabolic disorder inherited as an autosomal recessive trait. Spectrum of genetic variants in CBS gene and their correlation with the phenotypes of homocystinuria in Sri Lankan ...
Hewa Warawitage Dilanthi +10 more
doaj +2 more sources
New treatment for pyridoxine-dependent epilepsy due to ALDH7A1 deficiency: first proof-of-principle of upstream enzyme inhibition in the mouse. [PDF]
Brain Communvan Karnebeek CDM +12 more
europepmc +3 more sources
TRANSAMINASE AND PYRIDOXINE DEFICIENCY
Journal of Biological Chemistry, 1947 S R, AMES, P S, SARMA, C A, ELVEHJEM
openaire +3 more sources
Saudi Pharmaceutical Journal, 2023 Background: Diabetic Peripheral Neuropathy is one of the most important and significantly prevalent microvascular complications of Diabetes Mellitus. Pyridoxine is a key nutrient for protecting nerve health. The objective of this research is to study the
Moteb Khobrani +7 more
doaj +1 more source
Frontiers in Genetics, 2022 Objective: To analyze the clinical feature, treatment, and prognosis of epileptic spasms (ES) in vitamin B6–dependent epilepsy, including patients with pyridoxine-dependent epilepsy (PDE) caused by ALDH7A1 mutation, pyridox(am)ine-5′-phosphate oxidase ...
Xianru Jiao +4 more
doaj +1 more source
ACUTE IZONIAZID POISONING WITH PRESENTATION OF A CLINICAL CASE [PDF]
Journal of IMAB, 2022 Rimicid or isonide a group of medications which belong to anti-tuberculosis medicaments. The active substance isoniazid is used to treat pulmonary and extrapulmonary forms of tuberculosis, as well as prophylaxis in case of contact with infected ...
Evgenia Barzashka +3 more
doaj +1 more source
Effects of Pyridoxine on Growth Performance and Plasma Aminotransferases and Homocysteine of White Pekin Ducks [PDF]
Asian-Australasian Journal of Animal Sciences, 2014 A dose-response experiment with seven supplemental pyridoxine levels (0, 0.66, 1.32, 1.98, 2.64, 3.30, and 3.96 mg/kg) was conducted to investigate the effects of pyridoxine on growth performance and plasma aminotransferases and homocysteine of White ...
Ming Xie +4 more
doaj +1 more source
Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency) [PDF]
, 2010 Pyridoxine-dependent epilepsy was recently shown to be due to mutations in the ALDH7A1 gene, which encodes antiquitin, an enzyme that catalyses the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-{alpha}-aminoadipic semialdehyde/L-{Delta}
Adam +50 more
core +7 more sources
Epilepsy Phenotypes of Vitamin B6-Dependent Diseases: An Updated Systematic Review
Children, 2023 Background: Vitamin B6-dependent epilepsies include treatable diseases responding to pyridoxine or pyridoxal-5Iphosphate (ALDH7A1 deficiency, PNPO deficiency, PLP binding protein deficiency, hyperprolinemia type II and hypophosphatasia and ...
Mario Mastrangelo +5 more
doaj +1 more source