Results 181 to 190 of about 3,728 (241)
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Journal of Pharmaceutical Sciences, 1988
O-Demethylation of pyrilamine with l-propanethiol and potassium tert-butoxide gave hydroxytripelennamine, one of the major metabolites of tripelennamine. The reaction of pyrilamine with other demethylating agents has been explored and the products formed have been characterized.
F L, Hsu, S Y, Yeh, S, Munavalli
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O-Demethylation of pyrilamine with l-propanethiol and potassium tert-butoxide gave hydroxytripelennamine, one of the major metabolites of tripelennamine. The reaction of pyrilamine with other demethylating agents has been explored and the products formed have been characterized.
F L, Hsu, S Y, Yeh, S, Munavalli
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Jpc-journal of Planar Chromatography-modern Tlc, 2018
Two chromatographic methods were developed for the simultaneous determination of paracetamol, pamabrom, and pyrilamine maleate in bulk and combined pharmaceutical dosage form. The first method is an ultra-performance liquid chromatographic (UPLC) method,
N. Rashed +3 more
semanticscholar +1 more source
Two chromatographic methods were developed for the simultaneous determination of paracetamol, pamabrom, and pyrilamine maleate in bulk and combined pharmaceutical dosage form. The first method is an ultra-performance liquid chromatographic (UPLC) method,
N. Rashed +3 more
semanticscholar +1 more source
A Discussion of Pyrilamine Metabolite Identification: Reply
Journal of Analytical Toxicology, 1987 Walter A. Korfmacher
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Journal of Labelled Compounds and Radiopharmaceuticals, 1985
AbstractPyrilamine‐d6 (N‐[(4‐methoxyphenyl)methyl]‐N′, N′‐di[2H3]methyl‐N‐2‐pyridinyl‐1,2‐ethanediamine) was synthesised from N‐2‐[(4‐methoxyphenyl)methyl]‐aminopyridine and 2‐(N,N‐di[2H3]methylamino)ethyl chloride in 83% yield. The alkyl chloride was prepared in 37% overall yield in a three step reaction from toluene‐4‐sulphondi [2H3]methylamide.
Ian Bird, David E G Shuker
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AbstractPyrilamine‐d6 (N‐[(4‐methoxyphenyl)methyl]‐N′, N′‐di[2H3]methyl‐N‐2‐pyridinyl‐1,2‐ethanediamine) was synthesised from N‐2‐[(4‐methoxyphenyl)methyl]‐aminopyridine and 2‐(N,N‐di[2H3]methylamino)ethyl chloride in 83% yield. The alkyl chloride was prepared in 37% overall yield in a three step reaction from toluene‐4‐sulphondi [2H3]methylamide.
Ian Bird, David E G Shuker
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Ionic Radii of the Histadyl and Pyrilamine Cations
Journal of the American Chemical Society, 1955 A. C. Andrews +2 more
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Quantitative metabolic profile of tripelennamine and pyrilamine in the rat.
Drug Metabolism and Disposition, 1988 S Y, Yeh, F L, Hsu
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Chronic Feeding Study of Pyrilamine in Fischer 344 Rats
Fundamental and Applied Toxicology, 1995The antihistamine, pyrilamine maleate, was fed for up to 2 years to groups of 57 Fischer 344 (F344) rats of each sex at dietary levels of 0, 300, 1500, or 3000 ppm (free base). Eight or nine of these rats per sex and dose group were killed at 65 weeks to analyze hematology and clinical chemistry in all groups and histopathology of control and high-dose
D L, Greenman +4 more
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Identification of Pyrilamine Metabolites by Ammonia Chemical Ionization Mass Spectrometry
Journal of Analytical Toxicology, 1986The ammonia chemical ionization mass spectrometric analysis of pyrilamine, the N-oxide of pyrilamine, and related compounds is described. The use of ammonia as the reagent gas produced excellent [M + H]+ ions for these compounds. The suitability of this method for the analysis of two rat urinary metabolites of pyrilamine is demonstrated.
W A, Korfmacher +3 more
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Rectal Pyrilamine-Pentobarbital Compared with Promethazine for Vomiting in Children
Southern Medical Journal, 1968 R C TIBBS
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