Results 111 to 120 of about 34,530 (252)

Addressing the challenge of neonatal mortality.

, 2013
Reducing neonatal mortality remains a challenge with an estimated 3.0 million neonatal deaths in 2011, three-quarters of these in sub-Saharan Africa and Southern Asia.
Blencowe, H, Cousens, S
core   +1 more source

THE MODE OF ACTION OF A MIXTURE OF PYRIMETHAMINE AND SULPHADIMIDINE ON EIMERIA TENELLA [PDF]

, 1956
L Joyner, S.B. Kendall
openalex   +1 more source

Study of anti-Toxoplasma gondii effect of mPEG–PCL copolymeric loaded with pyrimethamine, in vitro

AMB Express
The discovery of new drugs with minimal toxicity is crucially important in the search for effective treatments for toxoplasmosis. The study aimed to assess the effectiveness of pyrimethamine-loaded mPEG–PCL copolymeric nanoparticles (mPEG–PCL–Pyr ...
Mobina Gholami, Hossein Danafer, Mitra Sadeghi, Ahmad Daryani, Seyed Abdollah Hosseini, Shirzad Gholami   +5 more
doaj   +1 more source

The impact of maternal antenatal treatment with two doses of azithromycin and monthly sulphadoxine-pyrimethamine on child weight, mid-upper arm circumference and head circumference: A randomized controlled trial.

PLoS ONE, 2019
AimIntermittent preventive treatment in pregnancy (IPTp) with azithromycin and monthly sulfadoxine-pyrimethamine increased the mean child weight, mid-upper arm and head circumference at four weeks of age in a rural low-income setting.
Lotta Hallamaa, Yin Bun Cheung, Mari Luntamo, Ulla Ashorn, Teija Kulmala, Charles Mangani, Per Ashorn   +6 more
doaj   +1 more source

NK cells as effectors of acquired immune responses: effector CD4+ T cell-dependent activation of NK cells following vaccination.

, 2010
We characterized vaccine-induced cellular responses to rabies virus in naive adult volunteers. Contrary to current paradigms, we observed potent and prolonged in vitro NK cell cytokine production and degranulation responses after restimulation of PBMCs ...
Behrens, Ron H, Fooks, Anthony R, Horowitz, Amir, Okell, Lucy, Riley, Eleanor M   +4 more
core   +1 more source

Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant [PDF]

, 2007
Natércia Fernandes, Paula Figueiredo, Virgı́lio E. do Rosário, Pedro Cravo   +3 more
openalex   +1 more source

Short Report: Association Between Chloroquine and Amodiaquine Resistance and Allelic Variation in the Plasmodium Falciparum Multiple Drug Resistance 1 Gene and the Chloroquine Resistance Transporter Gene in Isolates from the Upper Nile in Southern Sudan. [PDF]

, 2003
Amodiaquine, a 4-aminoquinoline compound, is being considered as an alternative to chloroquine and pyrimethamine/sulfadoxine where resistance in Plasmodium falciparum to both drugs has been selected.
Keus, K, Nzila, A, Ochong, E, van den Broek, I   +3 more
core   +1 more source

Developing Ontology Support for Human Malaria Control Initiatives [PDF]

, 2011
Malaria is one of the most common infectious diseases and an enormous public health problem in Sub-Sahara Africa, Asia and parts of America. In this paper, we discuss the development of the Human Malaria Control Ontology (HMCO) which contains ...
Daramola, Olawande, Fatumo, S.
core  

Efficacy and safety of single-dose artesunate plus sulfalene/pyrimethamine combined with praziquantel for the treatment of children with Schistosoma mansoni or Schistosoma haematobium in western Kenya: a randomised, open-label controlled trial

Parasites & Vectors
Background Reliance on praziquantel for the treatment and control of schistosomiasis is likely to facilitate the emergence of drug resistance. Combination therapy targeting adult and juvenile schistosome worms is urgently needed to improve praziquantel ...
Charles O. Obonyo, Fredrick O. Rawago, Nicholas K. Makworo, Erick M. O. Muok   +3 more
doaj   +1 more source

Structural Studies on Bioactive Compounds. Part 37.¹ Suzuki Coupling of Diaminopyrimidines: A New Synthesis of the Antimalarial Drug Pyrimethamine [PDF]

, 2002
Marianne L. Richardson, Malcolm F. G. Stevens   +1 more
openalex   +1 more source