Results 1 to 10 of about 791 (131)
Toxic epidermal necrolysis (TEN) is a rare life-threatening mucocutaneous reaction characterized by epidermal detachment. Treatment success relies on early diagnosis, rapid withdrawal of the causative drug and supportive care.
Alba Escolà-Rodríguez +6 more
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IntroductionAfter being used vigorously for the previous two decades to treat P. falciparum, chloroquine and sulfadoxine-pyrimethamine were replaced in 2009 with an artemisinin-based combination therapy (artesunate-sulfadoxine-pyrimethamine) in an effort
Sabyasachi Das +7 more
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Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells
Despite the severe morbidity caused by Zika fever, its specific treatment is still a challenge for public health. Several research groups have investigated the drug repurposing of chloroquine.
Audrien Alves Andrade de Souza +10 more
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Decreasing burden of malaria in pregnancy in Malawian women and its relationship to use of intermittent preventive therapy or bed nets. [PDF]
The World Health Organization recommends insecticidal bednets and intermittent preventive treatment to reduce malaria in pregnancy. Longitudinal data of malaria prevalence and pregnancy outcomes are valuable in gauging the impact of these antimalarial ...
Gaoqian Feng +4 more
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Haiti is striving for zero local malaria transmission by the year 2025. Chloroquine remains the first-line treatment, and sulfadoxine/pyrimethamine (SP) has been used for mass drug-administration pilot programs.
Eric Rogier +16 more
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DEVELOPMENT AND VALIDATION OF LC-MS METHOD FOR SIMULTANEOUS DETERMINATION OF PYRIMETHAMINE AND SULFADOXINE IN THE PHARMACEUTICAL PREPARATION [PDF]
A simple, sensitive, accurate and precise liquid chromatography mass spectrometry (LC-MS) method was developed for determination of pyrimethamine and sulfadoxine in pharmaceutical formulation.
Mohamed Nassar +3 more
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INTRODUCTION: La présente étude prospective se propose d'évaluer l'efficacité thérapeutique du traitement préventif intermittent à la sulfadoxine pyriméthamine et son observance chez la femme enceinte dans deux hôpitaux urbains au Burkina Faso. METHODES:
Sanata Bamba +6 more
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Sulfadoxine-resistant Plasmodium falciparum undermines malaria prevention with sulfadoxine/pyrimethamine. Parasites with a highly resistant mutant dihydropteroate synthase (dhps) haplotype have recently emerged in eastern Africa; they negated preventive ...
Steve M. Taylor +15 more
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Objectives: Because of lack of data on the prevalence of sulfadoxine antibody, this study was conducted to determine the prevalence of sulfadoxine antibodies and its possible risk factors.
Kingsley Ikuoyogie +2 more
doaj +1 more source
Assessment of the Teratogenic Effect of Sulfadoxine-Pyrimethamine on the Chicken Embryo
Background. The sulfadoxine-pyrimethamine combination is a product used in the intermittent preventive treatment (IPT) of malaria in pregnant women in our country. To date, there is very little data on the teratogenic effect of this product.
Rachida Moussa Tari +8 more
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