Results 31 to 40 of about 11,797 (221)

Origin and dissemination across the Colombian Andes mountain range of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum.

, 2010
The therapeutic efficacy of sulfadoxine-pyrimethamine (SP) in treating uncomplicated Plasmodium falciparum malaria is unevenly distributed in Colombia. The Andes mountain range separates regions in the west where malaria is endemic from those in the east
Osorio, Lyda, GUERRA, ANGELA, Echeverry, Diego F, Roper, Cally, Guerra, Angela P, ECHEVERRY, DIEGO, PEARCE, RICHARD, Corredor, Vladimir, CORREDOR ESPINEL, VLADIMIR, Murillo, Claribel, Benavides, Julie, Pearce, Richard J, Benavides Melo, Julie   +12 more
core   +1 more source

Effects of point mutations in Plasmodium falciparum dihydrofolate reductase and dihydropterate synthase genes on clinical outcomes and in vitro susceptibility to sulfadoxine and pyrimethamine. [PDF]

PLoS ONE, 2009
Sulfadoxine-pyrimethamine was a common first line drug therapy to treat uncomplicated falciparum malaria, but increasing therapeutic failures associated with the development of significant levels of resistance worldwide has prompted change to alternative
David J Bacon, Doug Tang, Carola Salas, Norma Roncal, Carmen Lucas, Lucia Gerena, Lorena Tapia, A Alejandro Llanos-Cuentas, Coralith Garcia, Lelv Solari, Dennis Kyle, Alan J Magill   +11 more
doaj   +1 more source

Sulfadoxine resistance in Plasmodium vivax is associated with a specific amino acid in dihydropteroate synthase at the putative sulfadoxine-binding site [PDF]

, 2004
Sulfadoxine is predominantly used in combination with pyrimethamine, commonly known as Fansidar, for the treatment of Plasmodium falciparum. This combination is usually less effective against Plasmodium vivax, probably due to the innate refractoriness of
Baker, J., Rieckmann, K., Cheng, Q., Chen, N. H., Korsinczky, M., Fischer, K.   +5 more
core   +1 more source

A Comparative Study of Advanced Oxidation Processes for the Removal of the Antibiotic Sulfadoxine from Water—Transformation Products and Toxicity

Applied Sciences
Sulfonamides, including sulfadoxine (SDX), are widely used antibiotics, particularly for malaria treatment. However, their extensive use has led to environmental pollution, microbial resistance, and public health risks. Advanced Oxidation Processes (AOPs)
Panagiotis A. Bizirtsakis, Kyriaki Anagnostopoulou, Vasilis C. Sarasidis, Panagiota Petsi, Alexandra Moschona, Konstantinos V. Plakas, Dimitra A. Lambropoulou   +6 more
doaj   +1 more source

Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

Malaria Journal, 2020
Background Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India,
Ashish Pathak, Andreas Mårtensson, Sudhir Gawariker, Ashish Sharma, Vishal Diwan, Manju Purohit, Johan Ursing   +6 more
doaj   +1 more source

The Effect of Artemisinin-Based Drugs vs Non-artemisinin-based Drugs on Gametophyte Carrying in the Body After the Treatment of Uncomplicated Falciparum Malaria: A Systematic Review and Meta-analysis

Frontiers in Pharmacology, 2022
The WHO recommends Artemisinin-based combination therapy (ACTs) as the first-line treatment for malaria. This meta-analysis aims to analyze the effects of artemisinin and its derivatives as well as non-artemisinin drugs on the gametophytes in the host ...
Yuanyuan Zou, Nadia Julie, Shiyuan Guo, Yexiao Tang, Hongying Zhang, Zhiyong Xu, Wanting Wu, Yueming Yuan, Zhibin Wu, Wenfeng Guo, Changqing Li, Xinan Huang, Qin Xu, Changsheng Deng, Jianping Song, Qi Wang, Qi Wang   +16 more
doaj   +1 more source

Outbreak of poisoning by sodium hydrogen methylarsonate (MSMA)—an arsenic‐based herbicide—in horses in Brazil

Equine Veterinary Journal, EarlyView.
Abstract Background Arsenic poisoning in horses is rarely reported in the literature. However, arsenic compounds can be present in rodenticides, pesticides, and herbicides, representing a potential source of accidental exposure for horses. Objective To describe the epidemiological, clinical, and laboratory findings from a herd of 31 horses exposed to ...
Gabriella Faria Pereira, Maria Clara Hornich Blimbliem, Anna Laura Previato Rosa Machado, Junara Bianca Rosa Abdala, Geison Morel Nogueira, Hugo Shisei Toma, Tatiane Furtado de Carvalho, Diego José Zanzarini Delfiol   +7 more
wiley   +1 more source

Enhancing Maternal and Child Health: A Cross‐National Analysis of Nutrition Service Readiness in Sub‐Saharan Africa

Maternal &Child Nutrition, EarlyView.
Large variations exist in the availability of essential nutrition commodities and services across seven sub‐Saharan African countries, highlighting disparities in health system readiness. Despite high procurement rates for key commodities, logistical challenges impede consistent service delivery at the facilities, especially for newer interventions ...
Romance Dissieka, Djeinam Toure, Akriti Singh, Mahamadou Mansour Ndiath, Rolf D. W. Klemm   +4 more
wiley   +1 more source

Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial.

, 2005
BACKGROUND: Many countries in Africa are considering a change to combination treatment for falciparum malaria because of the increase in drug resistance. However, there are few effectiveness data for these combinations.
Greenwood, Brian M, Hallett, Rachel, Mutabingwa, Theonest K, Drakeley, Chris, Whitty, Christopher JM, Anthony, Devota, Ahmed, Jalal, Heller, Archie   +7 more
core   +1 more source

Understanding Opportunity Costs of Women Participating in Maternal and Child Nutrition Interventions in Southern Angola: Evidence From the MuCCUA Trial

Maternal &Child Nutrition, Volume 22, Issue 3, July 2026.
Economic evaluations of multisectoral nutrition interventions often overlook participants' costs. Using MuCCUA trial data, we estimated women's opportunity costs of three maternal and child nutrition interventions in Angola. Remote participants faced burdens equivalent to 1–1.5 workdays monthly.
Rocio Martin‐Cañavate, Antonio Pujol‐de Castro, Chloe Puett, Elena Trigo, Maria de Lourdes Faria, Ana Silva Gerardo, Antonio Vargas, Israel Molina, Estefania Custodio   +8 more
wiley   +1 more source