Results 51 to 60 of about 791 (131)

Amitriptyline Induced Life‐Threatening Steven–Johnson Syndrome: Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Stevens–Johnson syndrome is one of the few dermatological emergencies in clinical practice. The syndrome is often secondary to the usage of drugs, of which allopurinol, penicillins, sulfa drugs, ibuprofen, sodium valproate, phenytoin, lamotrigine, and carbamazepine are commonly implicated.
Wondwosen Mengist Dereje, Lidya Yalew, Nardos Tafesse, Teklegiorgis Goshime Getachew   +3 more
wiley   +1 more source

New β-Lactam Compounds from Sulfadoxine Drug: Synthesis, Characterization, and Biological Activity

Indonesian Journal of Chemistry
Using ring-closure processes, new heterocyclic β-lactam derivatives of sulfadoxine were created. Sulfadoxine was reacted with several aromatic aldehydes under reflux in ethanol with glacial acetic acid to generate Schiff base intermediates (E6–E9). The β-
Nada Ali Salih, Nadia Sadiq Majeed
doaj   +1 more source

Trends and Patterns of Adverse Drug Reaction Reporting in Sierra Leone: A Retrospective Analysis of VigiFlow Data (2008–2022)

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 3, March 2026.
ABSTRACT Purpose Adverse drug reactions (ADRs) present significant obstacles for healthcare systems, impacting both patient safety and the effectiveness of treatments. Despite this, there is a scarcity of research on ADR reports in Sierra Leone, especially over long periods.
Isatu Jalloh, Onome Thomas Abiri, Peter Bai James, Rajesh Vagiri, Neelaveni Padayachee   +4 more
wiley   +1 more source

Childhood Linear Growth and Early Morbidity as Predictors of Adolescent Cognitive Ability in Malawi: A Prospective Observational Study

Acta Paediatrica, Volume 115, Issue 3, Page 634-642, March 2026.
ABSTRACT Aim Growth faltering and loss of development potential are common in low‐ and middle‐income countries. We aimed to study whether linear growth before and after 2 years, height‐for‐age Z‐score (HAZ) from 1 month until 13 years and morbidity during the first 3 years predict adolescent cognitive ability.
Karoliina Videman, Jukka M. Leppänen, Lotta Hallamaa, Kenneth Maleta, Per Ashorn, Charles Mangani, Ulla Ashorn   +6 more
wiley   +1 more source

Origin and evolution of sulfadoxine resistant Plasmodium falciparum.

PLoS Pathogens, 2010
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa ...
Sumiti Vinayak, Md Tauqeer Alam, Tonya Mixson-Hayden, Andrea M McCollum, Rithy Sem, Naman K Shah, Pharath Lim, Sinuon Muth, William O Rogers, Thierry Fandeur, John W Barnwell, Ananias A Escalante, Chansuda Wongsrichanalai, Frederick Ariey, Steven R Meshnick, Venkatachalam Udhayakumar   +15 more
doaj   +1 more source

Evidence of triple mutant Pfdhps ISGNGA haplotype in Plasmodium falciparum isolates from North-east India: An analysis of sulfadoxine resistant haplotype selection

Genomics Data, 2016
Background: North-east region of India has consistent role in the spread of multi drug resistant Plasmodium (P.) falciparum to other parts of Southeast Asia.
Manuj K. Das, Sumi Chetry, Mohan C. Kalita, Prafulla Dutta   +3 more
doaj   +1 more source

Spectrophotometric Estimation of Sulfadoxine in Pharmaceutical Preparations

E-Journal of Chemistry, 2010
Four simple, sensitive, accurate and rapid visible spectrophotometric methods (A, B, C and D) have been developed for the estimation of sulfadoxine in pharmaceutical preparations. They are based on the diazotization of sulfadoxine with sodium nitrite and
Sangita Sharma, Madhurjya Neog, Vipul Prajapati, Hiren Patel, Dipti Dabhi   +4 more
doaj   +1 more source

Sulfadoxine-pyrimethamine for uncomplicated falciparum malaria: Sulfadoxine-pyrimethamine is not working in Malawi [PDF]

BMJ, 2004
EDITOR—The paper by Plowe et al entitled “Sustained clinical efficacy of sulfadoxine-pyrimethamine for uncomplicated falciparum malaria” might be better titled “Sustained lack of efficacy of sulfadoxine-pyrimethamine….”1 By the start of the study period five years ago, molecular genotyping showed that Plasmodium falciparum in Malawi had already ...
openaire   +1 more source

Comparative Evaluation of the Dynamics of Parameters of Cell-Mediated Immunity under the Influence of Different Therapies for Chronic Acquired Toxoplasmosis

Aktualʹnaâ Infektologiâ, 2015
The article presents a comparative evaluation of the dynamics of parameters of cell-mediated immunity in patients under the influence of different therapies for chronic acquired toxoplasmosis (CAT).
O.V. Bobrova, Anuar al Hatib
doaj   +1 more source

Emergence of Plasmodium falciparum pfdhps A581G mutation in Southern Senegal under Seasonal Malaria Chemoprevention pressure, 2020-2023

Communications Medicine
Background: Malaria prevention in Senegal includes the use of Seasonal Malaria Chemoprevention with sulfadoxine-pyrimethamine plus amodiaquine. Prolonged use of sulfadoxine-pyrimethamine, however, can select for mutations in the Plasmodium falciparum ...
Mamadou Alpha Diallo, Abdoulaye Tine, Djiby Sow, Aita Sene, Amy Gaye, Yaye D. Ndiaye, Jules Gomis, Baba Dieye, Awa B. Deme, Mamadou S. Yade, Bassirou Ngom, Mamane N. Garba, Ibrahima M. Ndiaye, Khadim Diongue, Aida Sadikh Badiane, Mame Cheikh Seck, Mouhamadou Ndiaye, Daouda Ndiaye   +17 more
doaj   +1 more source