Results 11 to 20 of about 791 (131)

Mutaciones puntuales en los genes dhfr y dhps de Plasmodium falciparum de tres regiones endémicas

Biomédica: revista del Instituto Nacional de Salud, 2010
Introducción. La acumulación progresiva de mutaciones en los genes dhfr y dhps lleva al parásito Plasmodium falciparum a evadir la acción de la sulfadoxina-pirimetamina, situación que aumenta el nivel de resistencia del parásito a estos medicamentos y ...
John Alexander Galindo, Fabio Aníbal Cristiano, Angélica Knudson, Rubén Santiago Nicholls, Ángela Patricia Guerra   +4 more
doaj   +1 more source

Eficacia de la combinación amodiaquina más sulfadoxinapirimetamina y de la cloroquina para el tratamiento del paludismo en Córdoba, Colombia, 2006

Biomédica: revista del Instituto Nacional de Salud, 2008
Introducción. La disminución de la eficacia de los medicamentos antipalúdicos en el mundo y en Colombia, dificulta el control de la enfermedad. Objetivo.
Manuel Alberto Pérez, Liliana Jazmín Cortés, Ángela Patricia Guerra, Angélica Knudson, Carlos Usta, Rubén Santiago Nicholls   +5 more
doaj   +1 more source

Declining trend of Plasmodium falciparum dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) mutant alleles after the withdrawal of Sulfadoxine-Pyrimethamine in North Western Ethiopia. [PDF]

PLoS ONE, 2015
Antimalarial drug resistance is one of the major challenges in global efforts of malaria control and elimination. In 1998, chloroquine was abandoned and replaced with sulfadoxine/pyrimethamine, which in turn was replaced with artemether/lumefantrine for ...
Sofonias K Tessema, Moges Kassa, Amha Kebede, Hussein Mohammed, Gemechu Tadesse Leta, Adugna Woyessa, Geremew Tasew Guma, Beyene Petros   +7 more
doaj   +1 more source

Gametocitemia en malaria por Plasmodium falciparum tratada con amodiaquina o artesunato

Biomédica: revista del Instituto Nacional de Salud, 2008
Introducción. Las relaciones de la gametocitemia de Plasmodium falciparum con el tratamiento antipalúdico han sido poco estudiadas en América. Objetivo.
Jaime Carmona-Fonseca, Eliana Arango, Silvia Blair   +2 more
doaj   +1 more source

Gametocytaemia in senegalese children with uncomplicated Falciparum malaria treated with chloroquine, amodiaquine or sulfadoxine + pyrimethamine

Parasite, 2001
Plasmodium falciparum gametocytaemia was studied in 266 Senegalese children (median 4 years, range 0.5-16) with uncomplicated malaria treated with chloroquine (CQ), amodiaquine (AQ) or sulfadoxine+pyrimethamine (SP).
Sokhina C.S, Trape J.-F, Robert V.
doaj   +1 more source

Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso

Malaria Journal, 2004
The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille, Müller Olaf, Kouyate Bocar   +2 more
doaj   +1 more source

Deciphering the Impact of Mutations on PfDHPS Active Site and Sulfadoxine Binding: Structural Insights from Molecular Dynamics Simulations

Molecules
The antimalarial combination of sulfadoxine–pyrimethamine is used as a preventive treatment in pregnant women and children in Africa. Sulfadoxine inhibits the Plasmodium falciparum dihydropteroate synthase (PfDHPS), but resistance has emerged through ...
Emilie Guémas, Sandie Ménard, Nicolas Jeanne, Georges Landa, Antoine Berry, Marie Brut   +5 more
doaj   +1 more source

Differentials in prevalence and correlates on uptake of tetanus toxoid and intermittent preventive treatment with sulfadoxine-pyrimethamine during pregnancy: A community-based cross-sectional study in The Gambia

SAGE Open Medicine, 2022
Objectives: The study examined the differentials in prevalence and correlates on the uptake of tetanus toxoid and intermittent preventive treatment of malaria among pregnant women in The Gambia.
Amadou Barrow, Sulayman Barrow, Amienatta Jobe   +2 more
doaj   +1 more source

A Comparative Study of Advanced Oxidation Processes for the Removal of the Antibiotic Sulfadoxine from Water—Transformation Products and Toxicity

Applied Sciences
Sulfonamides, including sulfadoxine (SDX), are widely used antibiotics, particularly for malaria treatment. However, their extensive use has led to environmental pollution, microbial resistance, and public health risks. Advanced Oxidation Processes (AOPs)
Panagiotis A. Bizirtsakis, Kyriaki Anagnostopoulou, Vasilis C. Sarasidis, Panagiota Petsi, Alexandra Moschona, Konstantinos V. Plakas, Dimitra A. Lambropoulou   +6 more
doaj   +1 more source

Enhancing Maternal and Child Health: A Cross‐National Analysis of Nutrition Service Readiness in Sub‐Saharan Africa

Maternal &Child Nutrition, EarlyView.
Large variations exist in the availability of essential nutrition commodities and services across seven sub‐Saharan African countries, highlighting disparities in health system readiness. Despite high procurement rates for key commodities, logistical challenges impede consistent service delivery at the facilities, especially for newer interventions ...
Romance Dissieka, Djeinam Toure, Akriti Singh, Mahamadou Mansour Ndiath, Rolf D. W. Klemm   +4 more
wiley   +1 more source