Results 11 to 20 of about 11,797 (221)

Prevalence and Risk Factors for Sulfadoxine Antibody Among Patients Undergoing Treatment for Malaria in Benin City, Nigeria [PDF]

open access: yesOman Medical Journal, 2017
Objectives: Because of lack of data on the prevalence of sulfadoxine antibody, this study was conducted to determine the prevalence of sulfadoxine antibodies and its possible risk factors.
Kingsley Ikuoyogie   +2 more
doaj   +2 more sources

Efficacy of pyrimethamine-sulfadoxine in young children with uncomplicated falciparum malaria in rural Burkina Faso

open access: yesMalaria Journal, 2004
The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille   +2 more
doaj   +2 more sources

Origin and evolution of sulfadoxine resistant Plasmodium falciparum.

open access: yesPLoS Pathogens, 2010
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa ...
Sumiti Vinayak   +15 more
doaj   +3 more sources

Therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine and the sulfadoxine-pyrimethamine-amodiaquine combination against uncomplicated Plasmodium falciparum malaria in young children in Cameroon

open access: yesBulletin of the World Health Organization, 2002
OBJECTIVE: To evaluate the therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine, and the sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated Plasmodium falciparum malaria in young children in Cameroon.
Basco Leonardo K.   +6 more
doaj   +1 more source

Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance [PDF]

open access: yes, 2018
Fourteen novel arene RuII, and cyclopentadienyl (Cpx) RhIII and IrIII complexes containing an N,N′‐chelated pyridylimino‐ or quinolylimino ligand functionalized with the antimalarial drug sulfadoxine have been synthesized and characterized, including ...
Christina Tam   +36 more
core   +2 more sources

Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa. [PDF]

open access: yes, 2003
The selection of point mutation at codon 164 (from isoleucine to leucine) of the dihydrofolate reductase (DHFR) enzyme in Plasmodium falciparum is associated with high sulfadoxine /pyrimethamine (SP) resistance.
Watkins, W   +27 more
core   +1 more source

Assessment of the Teratogenic Effect of Sulfadoxine-Pyrimethamine on the Chicken Embryo

open access: yesJournal of Toxicology, 2022
Background. The sulfadoxine-pyrimethamine combination is a product used in the intermittent preventive treatment (IPT) of malaria in pregnant women in our country. To date, there is very little data on the teratogenic effect of this product.
Rachida Moussa Tari   +8 more
doaj   +1 more source

Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance. [PDF]

open access: yes, 2010
BACKGROUND: Intermittent Preventive Treatment of malaria in infants using sulfadoxine-pyrimethamine (SP-IPTi) is recommended by WHO for implementation in settings where resistance to SP is not high. Here we examine the relationship between the protective
Grobusch, Martin P.   +55 more
core   +1 more source

Traitement préventif intermittent à la sulfadoxine à pyriméthamine du paludisme chez les femmes enceintes: efficacité et observance dans deux hôpitaux urbains du Burkina Faso

open access: yesThe Pan African Medical Journal, 2013
INTRODUCTION: La présente étude prospective se propose d'évaluer l'efficacité thérapeutique du traitement préventif intermittent à la sulfadoxine pyriméthamine et son observance chez la femme enceinte dans deux hôpitaux urbains au Burkina Faso. METHODES:
Sanata Bamba   +6 more
doaj   +1 more source

Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. [PDF]

open access: yes, 2009
BACKGROUND: Malaria in pregnancy is serious, and drug resistance in Africa is spreading. Drugs have greater risks in pregnancy and determining the safety and efficacy of drugs in pregnancy is therefore a priority.
Greenwood, Brian M   +24 more
core   +1 more source

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