Prevalence and Risk Factors for Sulfadoxine Antibody Among Patients Undergoing Treatment for Malaria in Benin City, Nigeria [PDF]
Objectives: Because of lack of data on the prevalence of sulfadoxine antibody, this study was conducted to determine the prevalence of sulfadoxine antibodies and its possible risk factors.
Kingsley Ikuoyogie +2 more
doaj +2 more sources
The efficacy of pyrimethamine-sulfadoxine in the treatment of uncomplicated falciparum malaria in young children of a malaria holoendemic area in rural Burkina Faso is reported.
Traore Corneille +2 more
doaj +2 more sources
Origin and evolution of sulfadoxine resistant Plasmodium falciparum.
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa ...
Sumiti Vinayak +15 more
doaj +3 more sources
OBJECTIVE: To evaluate the therapeutic efficacy of sulfadoxine-pyrimethamine, amodiaquine, and the sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated Plasmodium falciparum malaria in young children in Cameroon.
Basco Leonardo K. +6 more
doaj +1 more source
Organometallic Conjugates of the Drug Sulfadoxine for Combatting Antimicrobial Resistance [PDF]
Fourteen novel arene RuII, and cyclopentadienyl (Cpx) RhIII and IrIII complexes containing an N,N′‐chelated pyridylimino‐ or quinolylimino ligand functionalized with the antimalarial drug sulfadoxine have been synthesized and characterized, including ...
Christina Tam +36 more
core +2 more sources
Molecular monitoring of the Leu-164 mutation of dihydrofolate reductase in a highly sulfadoxine/pyrimethamine-resistant area in Africa. [PDF]
The selection of point mutation at codon 164 (from isoleucine to leucine) of the dihydrofolate reductase (DHFR) enzyme in Plasmodium falciparum is associated with high sulfadoxine /pyrimethamine (SP) resistance.
Watkins, W +27 more
core +1 more source
Assessment of the Teratogenic Effect of Sulfadoxine-Pyrimethamine on the Chicken Embryo
Background. The sulfadoxine-pyrimethamine combination is a product used in the intermittent preventive treatment (IPT) of malaria in pregnant women in our country. To date, there is very little data on the teratogenic effect of this product.
Rachida Moussa Tari +8 more
doaj +1 more source
Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine-pyrimethamine and parasite resistance. [PDF]
BACKGROUND: Intermittent Preventive Treatment of malaria in infants using sulfadoxine-pyrimethamine (SP-IPTi) is recommended by WHO for implementation in settings where resistance to SP is not high. Here we examine the relationship between the protective
Grobusch, Martin P. +55 more
core +1 more source
INTRODUCTION: La présente étude prospective se propose d'évaluer l'efficacité thérapeutique du traitement préventif intermittent à la sulfadoxine pyriméthamine et son observance chez la femme enceinte dans deux hôpitaux urbains au Burkina Faso. METHODES:
Sanata Bamba +6 more
doaj +1 more source
Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. [PDF]
BACKGROUND: Malaria in pregnancy is serious, and drug resistance in Africa is spreading. Drugs have greater risks in pregnancy and determining the safety and efficacy of drugs in pregnancy is therefore a priority.
Greenwood, Brian M +24 more
core +1 more source

