Results 21 to 30 of about 791 (131)

Effects of point mutations in Plasmodium falciparum dihydrofolate reductase and dihydropterate synthase genes on clinical outcomes and in vitro susceptibility to sulfadoxine and pyrimethamine. [PDF]

PLoS ONE, 2009
Sulfadoxine-pyrimethamine was a common first line drug therapy to treat uncomplicated falciparum malaria, but increasing therapeutic failures associated with the development of significant levels of resistance worldwide has prompted change to alternative
David J Bacon, Doug Tang, Carola Salas, Norma Roncal, Carmen Lucas, Lucia Gerena, Lorena Tapia, A Alejandro Llanos-Cuentas, Coralith Garcia, Lelv Solari, Dennis Kyle, Alan J Magill   +11 more
doaj   +1 more source

Outbreak of poisoning by sodium hydrogen methylarsonate (MSMA)—an arsenic‐based herbicide—in horses in Brazil

Equine Veterinary Journal, Volume 58, Issue 5, Page 1258-1268, September 2026.
Abstract Background Arsenic poisoning in horses is rarely reported in the literature. However, arsenic compounds can be present in rodenticides, pesticides, and herbicides, representing a potential source of accidental exposure for horses. Objective To describe the epidemiological, clinical, and laboratory findings from a herd of 31 horses exposed to ...
Gabriella Faria Pereira, Maria Clara Hornich Blimbliem, Anna Laura Previato Rosa Machado, Junara Bianca Rosa Abdala, Geison Morel Nogueira, Hugo Shisei Toma, Tatiane Furtado de Carvalho, Diego José Zanzarini Delfiol   +7 more
wiley   +1 more source

Assessment of Nutritional and Nonnutritional Correlates of Anemia in Pregnancy: A Hospital‐Based Cross‐Sectional Study for Public Health Interventions in the Bono East Region of Ghana

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Anemia in pregnancy (AiP) remains a public health concern in Ghana. The Bono East Region is known for a variety of maternal morbidities, yet the association between inadequate intake of iron‐rich foods and AiP remains underexplored.
Dennis Bardoe, Joana Apenkwa, Daniel Hayford, Ernest Osei, Robert Bagngmen Bio, Salma Bardoe Ahmed   +5 more
wiley   +1 more source

Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India

Malaria Journal, 2020
Background Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. In Ujjain, central India,
Ashish Pathak, Andreas Mårtensson, Sudhir Gawariker, Ashish Sharma, Vishal Diwan, Manju Purohit, Johan Ursing   +6 more
doaj   +1 more source

The Effect of Artemisinin-Based Drugs vs Non-artemisinin-based Drugs on Gametophyte Carrying in the Body After the Treatment of Uncomplicated Falciparum Malaria: A Systematic Review and Meta-analysis

Frontiers in Pharmacology, 2022
The WHO recommends Artemisinin-based combination therapy (ACTs) as the first-line treatment for malaria. This meta-analysis aims to analyze the effects of artemisinin and its derivatives as well as non-artemisinin drugs on the gametophytes in the host ...
Yuanyuan Zou, Nadia Julie, Shiyuan Guo, Yexiao Tang, Hongying Zhang, Zhiyong Xu, Wanting Wu, Yueming Yuan, Zhibin Wu, Wenfeng Guo, Changqing Li, Xinan Huang, Qin Xu, Changsheng Deng, Jianping Song, Qi Wang, Qi Wang   +16 more
doaj   +1 more source

Pre‐Eclampsia and Its Associated Factors Among Pregnant Women in Ghana: A Retrospective Study

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Pre‐eclampsia remains a major cause of feto‐maternal death in Ghana, with a rising incidence linked to multiple factors that hinder prevention. Despite it's impact, few studies have explored associated risks. This study assessed the prevalence, risk factors, and maternal–neonatal outcomes associated with pre‐eclampsia among
Sabastian Adjei, Wilfred Sam‐Awortwi Jnr, Richmond Adu Boahen Boamah, Edward Osei Gyimah, William Kweku Payne, Harriet Yeboaa Diawuo, Samuel Kwame Sopuruchi Agomuo, Oscar Simon Olympio Mensah, Alfred Effah, Christian Obirikorang   +9 more
wiley   +1 more source

Discovery of Potent Antimalarial Agents Targeting Plasmodium falciparum DNA Gyrase B by Integrating Computational and Experimental Approaches

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
An integrated computational and experimental drug‐discovery approach identified UNC8153 as a potential novel scaffold active against drug‐sensitive and artemisinin‐resistant P. falciparum strains through inhibition of apicoplast PfGyrB. ABSTRACT The global spread of drug‐resistant Plasmodium falciparum, particularly artemisinin‐resistant strains ...
Biswajit Naik, Welka Sahu, Guneswar Sethi, Cherish Prashar, Gajendra Mohan Baldodiya, Jyoti Poswal, Chandi C. Mandal, Jeong Ho Hwang, Kailash C. Panday, K. Sony Reddy, Dhaneswar Prusty   +10 more
wiley   +1 more source

Understanding Opportunity Costs of Women Participating in Maternal and Child Nutrition Interventions in Southern Angola: Evidence From the MuCCUA Trial

Maternal &Child Nutrition, Volume 22, Issue 3, July 2026.
Economic evaluations of multisectoral nutrition interventions often overlook participants' costs. Using MuCCUA trial data, we estimated women's opportunity costs of three maternal and child nutrition interventions in Angola. Remote participants faced burdens equivalent to 1–1.5 workdays monthly.
Rocio Martin‐Cañavate, Antonio Pujol‐de Castro, Chloe Puett, Elena Trigo, Maria de Lourdes Faria, Ana Silva Gerardo, Antonio Vargas, Israel Molina, Estefania Custodio   +8 more
wiley   +1 more source

Determinants of Low Birth Weight in Ghana: Analysis of the 2022 Demographic and Health Survey

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Low birth weight (LBW) remains a significant public health challenge in developing countries, contributing substantially to infant mortality and morbidity. Objective To examine sociodemographic, maternal health, and healthcare utilization factors associated with low birth weight in Ghana.
Michael Arthur Ofori, David Kwamena Mensah, Theophilus Asamoah, Michael Fosu Ofori   +3 more
wiley   +1 more source

The impact of maternal antenatal treatment with two doses of azithromycin and monthly sulphadoxine-pyrimethamine on child weight, mid-upper arm circumference and head circumference: A randomized controlled trial.

PLoS ONE, 2019
AimIntermittent preventive treatment in pregnancy (IPTp) with azithromycin and monthly sulfadoxine-pyrimethamine increased the mean child weight, mid-upper arm and head circumference at four weeks of age in a rural low-income setting.
Lotta Hallamaa, Yin Bun Cheung, Mari Luntamo, Ulla Ashorn, Teija Kulmala, Charles Mangani, Per Ashorn   +6 more
doaj   +1 more source