Results 101 to 110 of about 643,096 (374)
Microorganisms‘Candidatus Phytoplasma mali’ is associated with apple proliferation, a devastating disease in fruit production. Using genome analysis, a gene encoding a hemolysin-like protein was identified.
Kajohn Boonrod +3 more
doaj +1 more source
Solvable models of neighbor-dependent nucleotide substitution processes [PDF]
arXiv, 2005 We prove that a wide class of models of Markov neighbor-dependent substitution processes on the integer line is solvable. This class contains some models of nucleotide substitutions recently introduced and studied empirically by molecular biologists. We show that the polynucleotide frequencies at equilibrium solve explicit finite-size linear systems ...
arxiv
Re-utilization of pyrimidine nucleotides during rat liver regeneration.
Biochemical Journal, 1985 The changes in the specific radioactivities of the pool of total acid-soluble uridine nucleotides and of uridine and cytidine components of total cellular and nuclear RNA were monitored in regenerating rat liver for 12 days after partial hepatectomy ...
E. Nikolov, M. Dabeva
semanticscholar +1 more source
Symmetry Scheme for Amino Acid Codons
, 2003 Group theoretical concepts are invoked in a specific model to explain how only twenty amino acids occur in nature out of a possible sixty four. The methods we use enable us to justify the occurrence of the recently discovered twenty first amino acid ...
F. Zinoni +11 more
core +1 more source
Journal of Magnetic Resonance Open, 2022 In this work a rapid RNA assignment approach by combining chemical and enzymatic 13C and 15N stable isotope labeling is introduced. We exemplify the assignment strategy for imino N1H1 purine and N3H3 pyrimidine and aromatic C6H6 pyrimidine, C8H8 purine ...
David Klingler +3 more
doaj
Lie Markov models with purine/pyrimidine symmetry [PDF]
arXiv, 2012 Continuous-time Markov chains are a standard tool in phylogenetic inference. If homogeneity is assumed, the chain is formulated by specifying time-independent rates of substitutions between states in the chain. In applications, there are usually extra constraints on the rates, depending on the situation.
arxiv
Lie Markov models with purine/pyrimidine symmetry [PDF]
, 2013 Continuous-time Markov chains are a standard tool in phylogenetic inference. If homogeneity is assumed, the chain is formulated by specifying time-independent rates of substitutions between states in the chain.
Fernández-Sánchez, Jesús +3 more
core +2 more sources
Symmetry Analysis Of Genetic Code And Determinative Degree (in Russian) [PDF]
arXiv, 2000 A three-dimensional model of the genetic vocabulary is proposed in terms of determinative degree, an introduced characteristic of nucleotide, which reflects absolute difference between purin and pyrimidin bases in one DNA strand. In the fremework of this model manifest symmetry and group properties are described. It is proposed to use the determinative
arxiv
A flexible model-based framework for robust estimation of mutational signatures [PDF]
arXiv, 2022 Somatic mutations in cancer can be viewed as a mixture distribution of several mutational signatures, which can be inferred using non-negative matrix factorization (NMF). Mutational signatures have previously been parametrized using either simple mono-nucleotide interaction models or general tri-nucleotide interaction models. We describe a flexible and
arxiv
Angewandte Chemie International Edition, Accepted Article.Pseudouridine‐5’‐triphosphate (ΨTP) and the N1‐methylated derivative (m1ΨTP) are critical monomer building blocks of the currently used mRNA vaccines, yet efficient methods of their synthesis from readily accessible substrates remain underdeveloped. We herein report notably atom‐economic and high‐yielding biocatalytic route toward ΨTP (83% yield) and ...
Martin Pfeiffer +4 more
wiley +1 more source