Results 71 to 80 of about 2,096 (140)
Crystalizing the genetic code [PDF]
arXiv, 2000 New developments are presented in the framework of the model introduced by the authors in refs. [1,2] and in which nucleotides as well as codons are classified in crystal bases of the quantum group U_q(sl(2)+sl(2)) in the limit q -> 0. An operator which gives the correspondence between the amino-acids and the codons is now obtained for any known ...
arxiv
Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]
arXiv, 2020 A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv
Bilayer Graphene Lateral Contacts for DNA Sequencing [PDF]
arXiv, 2012 Translocation of DNA through a nanopore with embedded electrodes is at the centre of new rapid inexpensive sequencing methods which allow distinguishing the four nucleobases by their different electronic structure. However, the subnanometer separation between nucleotides in DNA requires ultra-sharp probes.
arxiv
PLoS Pathogens, 2014 Microsporidia are obligate intracellular parasites of most animal groups including humans, but despite their significant economic and medical importance there are major gaps in our understanding of how they exploit infected host cells.
Eva Heinz +11 more
doaj +1 more source
A simple stochastic model to describe the evolution over time of core genome SNP GC content in prokaryotes [PDF]
arXiv, 2019 Genomes in living organisms consist of the nucleotides adenine (A), guanine (G), cytosine (C) and thymine (T). All prokaryotes have genomes consisting of double-stranded DNA, where the A's and G's (purines) of one strand bind respectively to the T's and C's (pyrimidines) of the other. As such, the number of A's on one strand nearly equals the number of
arxiv
eLife, 2015 In Arabidopsis thaliana, abundant 24 nucleotide small interfering RNAs (24 nt siRNA) guide the cytosine methylation and silencing of transposons and a subset of genes.
Todd Blevins +7 more
doaj +1 more source
Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancerResearch in context
EBioMedicine, 2023 Summary: Background: Pyrimidine nucleotides fuel the growth of colorectal cancer (CRC), making their associated proteins potential targets for cancer intervention.
Weili Wu +10 more
doaj
eLife, 2018 Ribosome degradation through the autophagy-lysosome pathway is crucial for cell survival during nutrient starvation, but whether it occurs under normal growth conditions and contributes to animal physiology remains unaddressed.
Yubing Liu +6 more
doaj +1 more source
A Comparative Experimental and Theoretical Study on Doubly Differential Electron-Impact Ionization Cross Sections of Pyrimidine [PDF]
To provide a comprehensive data set for track structure-based simulations of radiation damage in DNA, doubly differential electron-impact ionization cross sections of pyrimidine, a building block of the nucleobases cytosine and thymine, were measured for primary electron energies between 30 eV and 1 keV as a function of emission angle and secondary ...
arxiv +1 more source
Pyrimidine Nucleotide Metabolism and Pathways of Thymidine Triphosphate Biosynthesis in Salmonella typhimurium [PDF]
, 1968 Jan Neuhard
openalex +1 more source