Results 161 to 170 of about 11,360 (191)
Journal of Veterinary Pharmacology and Therapeutics, EarlyView.ABSTRACT Trimethoprim (TMP)‐sulfonamide combinations are widely used in veterinary medicine, yet the quantitative nature of their pharmacodynamic interaction remains incompletely characterised. This study investigated the interaction between TMP and sulfamethoxazole (SMX), sulfadiazine (SDZ) and sulfadimethoxine (SDMX) against two Staphylococcus ...
Andrew Mead +7 more
wiley +1 more source
Obesity Reviews, EarlyView.ABSTRACT Obesity arises from intertwined and reciprocal diet‐microbiome‐host pathways that reshape energy balance, insulin sensitivity, and inflammation. This review synthesizes mechanistic links between microbial functions and metabolic control, charts lifestyle‐related lifecourse dynamics from birth to older age, examines how GLP‐1‐based therapies ...
Ioanna Panagiota Kalafati +12 more
wiley +1 more source
Obesity Reviews, EarlyView.ABSTRACT Background Obesity's global rise has outpaced the effectiveness of “one‐size‐fits‐all” prevention and treatment strategies. The promise of precision medicine lies in addressing the etiological and biological diversity of obesity and transforming it into actionable endotypes.
Nadia Abu Samra +13 more
wiley +1 more source
Molecular Links Between Heat Stress and DNA Damage Response in Plants
Plant, Cell &Environment, EarlyView.ABSTRACT Climate change poses a major threat to agricultural productivity and, consequently, to global food security. Among the consequences of climate change, heat stress (HS) has emerged as a critical factor limiting crop performance. This has stimulated extensive research over the past decade to elucidate the molecular and physiological mechanisms ...
Adrian Calves‐Ubach +1 more
wiley +1 more source
Psychiatry and Clinical Neurosciences, EarlyView.Aim The link between violence‐related epigenetic changes and attentional problems (APs) is still not well understood. This article examines if exposure to family and community violence during childhood and adolescence may shape DNA methylation patterns associated with attention in youth.
Renata Queiroz Ramos +6 more
wiley +1 more source
Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source
Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation
Photochemistry and Photobiology, Volume 101, Issue 2, Page 517-526, March/April 2025.To directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, five subjects were exposed to 222‐nm UVC at doses of 22, 50, and 75 mJ/cm2. The findings indicate that far‐UVC irradiation does not cause “clinically significant photokeratitis” or long‐term ocular damage, though it may induce temporary discomfort.
Kazunobu Sugihara +3 more
wiley +1 more source
Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes
Photochemistry and Photobiology, EarlyView.Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto +8 more
wiley +1 more source
Depth of DNA photodamage in human corneas exposed to 222 nm or 254 nm UV
Photochemistry and Photobiology, EarlyView.Representative confocal 3D image of a section of a human cornea showing nuclei in blue (Hoechst 33342) and green, which was assigned to cells exhibiting Alexa555 conjugated to anti‐CPD antibody. The depth of photodamage was measured in Z‐stacks of the human corneal epithelium after exposure of the anterior surface to 50 or 100 mJ/cm2 at 222 or 254 nm ...
Manuela Buonanno +6 more
wiley +1 more source
Advances in organic UV filters for sunscreens over the past decade
Photochemistry and Photobiology, EarlyView.Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon +4 more
wiley +1 more source