PMO's protective wrap: Unraveling its surfactant-mediated stabilization for next-generation antisense therapies. [PDF]
Sharma SN, Gupta A, Sinha S.
europepmc +1 more source
On why cancer cells require a great amount of glucose
Abstract The traditional thinking has been that cancer cells require a great amount of glucose to support their rapid growth, but the reality may be different. We have previously demonstrated that all cancer cells in The Cancer Genome Atlas harbor persistent Fenton reactions in their cytosol, which generate OH− ${\text{OH}}^{-}$ and ultimately kill the
Xuechen Mu +6 more
wiley +1 more source
One‐Pot Amidation/C─H Halogenation by an Efficient Electrochemical Cascade
A sustainable electrochemical cascade enables the one‐pot synthesis of regioselectively halogenated N‐aryl amides from readily available amines and acyl halides under mild conditions. The method merges amidation and C─H halogenation in a single operational step, delivering broad substrate scope, high selectivity, and scalability, and provides an ...
Sudipta Ponra +8 more
wiley +2 more sources
Correction: Salinas-Giegé et al. tRNA Biology in Mitochondria. <i>Int. J. Mol. Sci.</i> 2015, <i>16</i>, 4518-4559. [PDF]
Salinas-Giegé T, Giegé R, Giegé P.
europepmc +1 more source
Merging Micellar Catalysis and C–H Activation: Silver‐Free Direct Arylation of Fluoroarenes in Water
We have developed the first silver‐free protocol for a palladium‐catalyzed direct arylation in water under micellar conditions enabling the coupling of diverse pyridine and fluoroarene derivatives. This method combines the sustainability of aqueous media with the efficiency of C–H activation, obviating the need for organic co‐solvents or stoichiometric
Federico Belnome +9 more
wiley +1 more source
Metabolism of Epigenetic Ribonucleosides Leads to Nucleolar Stress and Cytotoxicity. [PDF]
Sun X +8 more
europepmc +1 more source
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Mechanistic Insights into the Stabilizing Role of Deep Eutectic Solvents for Nucleic Acids: An <i>In Silico</i> Analysis. [PDF]
Hardy DE +5 more
europepmc +1 more source
Disclosing New Insights on Pyrazolo[3,4-<i>d</i>] Pyrimidine Tethered Diverse Amino Acid Candidates as Potential DHFR Inhibitors and Anti-Virulence Agents. [PDF]
Ibrahim TS +4 more
europepmc +1 more source

