Results 211 to 220 of about 48,617 (303)

Kinetic mechanisms for the sequence dependence of transcriptional errors. [PDF]

Proc Natl Acad Sci U S A
Midha T, Kolomeisky AB, Igoshin OA.
europepmc   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source

Skeletal editing of 4-arylpyrimidines into diverse nitrogen heteroaromatics via four-atom synthons. [PDF]

Nat Commun
Li S, Shi Y, Tang J, Yan M, Huang S, Dou T, Wang S, Jin X, Su Z, Jiang W, Xu J, Zheng X, Li R, Chen H, Xue W, Fu H.   +15 more
europepmc   +1 more source

Photoprotective potential of gadusol against ultraviolet B radiation in melanocytes

Photochemistry and Photobiology, EarlyView.
Gadusol protects melanocytes from ultraviolet B (UVB)‐induced damage without cytotoxicity. Abstract The increasing incidence of skin cancer, including melanoma, combined with the need for ultraviolet (UV) filters that are safe for human health and marine ecosystems, is driving the search for new photoprotective agents.
Andressa Mai Matsumoto, Rocío Isla Naveira, Andy Joel Taipe Huisa, Marcelo Augusto Germani Marinho, Lais Zortéa, José María Monserrat, Agueda Elena Massa, María Sandra Churio, Ana Paula de Souza Votto   +8 more
wiley   +1 more source

A universal polyphosphate kinase powers in vitro transcription. [PDF]

Nat Commun
Matsumoto R, Watanabe T, Yamazaki E, Kagawa A, Longo LM, Matsuura T.   +5 more
europepmc   +1 more source

Depth of DNA photodamage in human corneas exposed to 222 nm or 254 nm UV

Photochemistry and Photobiology, EarlyView.
Representative confocal 3D image of a section of a human cornea showing nuclei in blue (Hoechst 33342) and green, which was assigned to cells exhibiting Alexa555 conjugated to anti‐CPD antibody. The depth of photodamage was measured in Z‐stacks of the human corneal epithelium after exposure of the anterior surface to 50 or 100 mJ/cm2 at 222 or 254 nm ...
Manuela Buonanno, Istvan R. Boldogh, Raabia Hashmi, Camryn Petersen, David Welch, Theresa C. Swayne, David J. Brenner   +6 more
wiley   +1 more source

Genetic analysis of pyrimidine biosynthetic enzymes in Plasmodium falciparum. [PDF]

PLoS Pathog
Rajaram K, Sievert ML, Elahi R, Blauwkamp J, Dillard LB, Absalon S, Prigge ST.   +6 more
europepmc   +1 more source

Advances in organic UV filters for sunscreens over the past decade

Photochemistry and Photobiology, EarlyView.
Highlighted organic UV filter frameworks that have been described for sunscreens over the past decade divided into three groups: derivatives of or inspired by approved organic UV filters, natural product‐based compounds, and miscellaneous. Abstract Ultraviolet (UV) radiation is a major environmental factor in photoaging, erythema, and skin cancer ...
Gabriela Zanella Marcon, Maria Carolina Theisen, Andressa Motta Castro, Giovana Jones Radke, Fernando Fumagalli   +4 more
wiley   +1 more source

Preparation and characterization of kaolin-[TMS]-NH₂ ⁺C(NO₂)₃ ^- as a novel heterogeneous nano-catalyst and its use in the synthesis of imidazo[1,2-<i>a</i>]pyrimidine and 1,2,4-triazolo[4,3-<i>a</i>]pyrimidines. [PDF]

RSC Adv
Dorostkar M, Nazemi-Nasyrmahale L, Shirini F.   +2 more
europepmc   +1 more source

Development of chalcones structure‐related to avobenzone: Photoprotection, photostability, and safety evaluation

Photochemistry and Photobiology, EarlyView.
Scaffold hopping strategy used to develop chalcones structure‐related to the avobenzone tautomer. Positive aspects of 2‐hydroxychalcones are highlighted. Abstract Chalcones are α,β‐unsaturated ketones with extended π‐conjugation, making them promising scaffolds for the development of organic UV filters.
Gabriela Zanella Marcon, Taíne de Bastos Brum, Nayara Fernanda Tokashike de Araujo, Gabriela Lascala Ramos, Bruna Cogo Borin, Ruth Barin, Aline Ferreira Ourique, André Passaglia Schuch, Andréa Inês Horn Adams, Lorena Rigo Gaspar Cordeiro, Letícia Cruz, Fernando Fumagalli   +11 more
wiley   +1 more source