Results 221 to 230 of about 48,430 (295)

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

<i>p</i>TSA-catalyzed synthesis of functionalized chromeno[2,3-<i>d</i>]pyrimidine/chromeno[4,3-<i>b</i>]chromene derivatives <i>via</i> one-pot three component reaction: mechanistic insights and variable temperature NMR studies to investigate restricted bond rotation. [PDF]

RSC Adv
Singh Tanwer YB, Sourabh S, Bhunia S, Pal S, Das D.   +4 more
europepmc   +1 more source

Preliminary Evaluation of In Situ Chemical Oxidation Effects on Soil Carbon Dioxide Emission in a Soil Slurry System

Remediation Journal, Volume 36, Issue 2, Spring 2026.
ABSTRACT In situ chemical oxidation (ISCO), a remediation technology for soil and groundwater contamination, utilizes oxidants that can impact the soil environment and indirectly influence soil CO2 emissions. Understanding these emissions may support more sustainable ISCO applications by enabling adjustments to treatment conditions that limit ...
Wei‐Jiun Wang, Chenju Liang
wiley   +1 more source

5-Amino- and 6-amino-uracils in the synthesis of various heterocycles as therapeutic agents: a review. [PDF]

RSC Adv
Aly AA, Osman EM, Mostafa SM, Bedair TM, Abd-Elmonem M, Sadek KU, Mohamed AH.   +6 more
europepmc   +1 more source

Metabolic Fingerprints of High‐Risk Individuals for Pancreatic Cancer: A Multibiospecimen Investigation

Analysis &Sensing, Volume 6, Issue 4, July 2026.
This study presents a multimatrix untargeted metabolomics analysis of fecal, plasma, and urine samples from individuals at high risk for pancreatic cancer development. Integrated multivariate and cofactor‐adjusted models were applied to characterize cross‐matrix metabolomic associations, incorporating pancreatic magnetic resonance imaging data, sex ...
Vladyslav Dovhalyuk, Quang‐Dong Bui, Vincent Ripoll, Wiktor Rutkowski, Miroslav Vujasinovic, J.‐Matthias Löhr, Daniel Globisch   +6 more
wiley   +1 more source

Oxone®-mediated Dakin-like reaction to synthesize hydroxyarenes: an approach using pyrazolo[1,5-<i>a</i>]pyrimidines. [PDF]

RSC Adv
Cifuentes C, Cubides M, Portilla J.
europepmc   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

DNA base pairs: the effect of the aromatic ring on the strength of the Watson-Crick hydrogen bonding.

Org Biomol Chem
Nieuwland C, van Well MJ, Guillaumes L, de Vey Mestdagh A, Dekker L, Nieuweboer C, Simon S, Fonseca Guerra C.   +7 more
europepmc   +1 more source

Supramolecular Efficient Catalysis for Multicomponent Synthesis of Fused Indeno-pyrido[2,3‑<i>d</i>]pyrimidines as <i>Staphylococcal Thioredoxin Reductase</i> (<i>Sa</i>TrxR) Inhibitor Leads. [PDF]

ACS Omega
Bhosle MR, Belambe AV, Yadav VK, Bhati AS, Talekar SS, Bondle GM, Mane MV, Bhattacharyya S.   +7 more
europepmc   +1 more source