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Synthesis of Novel Classes of Pyrido[2,3‐d]‐pyrimidines, Pyrano[2,3‐d]pyrimidines, and Pteridines [PDF]
6-Amino-5-formyluracils 1 and 5-formyl-6-hydroxyuracils 4 react with Meldrum 19sacid2inthepresenceofpiperidineascatalystunderthermolyticconditions to afford 6-carboxy-2,4,7-trioxopyrido[2,3-d]pyrimidines 3 and 6-carboxy-2,4,7trioxopyrano[2,3-d ...
Pulak J Bhuyan
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Pyrimidines. XIII. Novel pyrimidine to pyrimidine transformation reactions
Journal of Heterocyclic Chemistry, 1977AbstractNovel pyrimidine to pyrimidine transformation reactions are described. 1,3‐Dimethyl‐(or diethyl)‐uracil(1) are converted into isocytosine, 2‐thiouracil or uracil derivatives by treatment with guanidine, thiourea or urea, respectively. The latter two cases require base catalysis. The effects of some substituents at C‐5 and C‐6 of 1,3‐dialkylated
Kosaku Hirota +2 more
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The Auger spectroscopy of pyrimidine and halogen-substituted pyrimidines
The Journal of Chemical Physics, 2008The C 1s and N 1s Auger spectra of pyrimidine, 2-chloropyrimidine, and 5-bromopyrimidine have been measured in an electron impact experiment at 1000 eV. In the case of the halogen-substituted pyrimidines, also the Cl 2p and Br 3d Auger spectra have been recorded.
Storchi L +5 more
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ChemInform Abstract: PYRIMIDINES. XIII. NOVEL PYRIMIDINE TO PYRIMIDINE TRANSFORMATION REACTIONS
Chemischer Informationsdienst, 1977AbstractBei der Behandlung mit Guanidin (II) erhält man aus 1,3‐Dimethyluracil sowie den . analogen Verbindungen (I) die Pyrimidinone (III).
K. HIROTA, K. A. WATANABE, J. J. FOX
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Anticancer pyrimidines, pyrimidine nucleosides and prodrugs
1990Of the plethora of pyrimidines, pyrimidine nucleosides, analogues and prodrug derivatives that have been synthesised and evaluated as anticancer agents, only two are in general clinical use. The long-studied 5-fluorouracil (5-FUra (1), see Scheme 9.1), and some nucleoside and prodrug derivatives, are used regularly for the treatment of breast cancer ...
M. MacCoss, M. J. Robins
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