Results 231 to 240 of about 48,430 (295)

Oxaliplatin‐induced neuropathy after total neoadjuvant therapy for rectal cancer: Dose–response relationship and impact on quality of life

International Journal of Cancer, Volume 159, Issue 1, Page 198-209, 1 July 2026.
What's New? Oxaliplatin serves a key role in the treatment of rectal cancer, though it is a significant cause of chemotherapy‐induced peripheral neuropathy. As total neoadjuvant therapy, in which all therapy is given before surgery, has become more common, understanding neuropathy has grown increasingly important. This study examined neuropathy and its
Georg W. Wurschi, Andreas Hinz, Melanie Schneider, Jan‐Niklas Becker, Bernd Frerker, Samuel M. Vorbach, Felix Ehret, Markus Diefenhardt, Fabian Schunn, Maria‐Elena von Gruben, Marcel Büttner, Elgin Hoffmann, Alexander Rühle, Josephine Beier, Simone Ferdinandus, Maike Trommer, Ezgi Ceren Sahin, Julian Hlouschek, Kynann Aninditha, Daphne Schepers von Ohlen, Justus Kaufmann, Alina Depardon, Hai Minh Ha, Christopher Kessler, Adrianna Cieslak, Simon Trommer, Alexander Fabian, Florian Rißner, Maximilian Römer, Klaus Pietschmann   +29 more
wiley   +1 more source

Efficient Approaches to the Design of Six-Membered Polyazacyclic Compounds-Part 1: Aromatic Frameworks. [PDF]

Molecules
Gyrgenova EA, Titova YY, Ivanov AV.
europepmc   +1 more source

An Exploration of Vinamidinium Salts for Frame‐Shifted Synthesis

Israel Journal of Chemistry, Volume 66, Issue 4, July 2026.
Oligoheterocycles are widely used in drug discovery and materials science, where they serve as attractive alternatives to peptide fragments. There is strong interest in understanding the structural correspondence between heterocycles and amino acid motifs to recapitulate key binding elements while improving metabolic stability.
Morgan J. Cordell, Chelsey Brien, Thomas Sidarta Setio, Andrei K. Yudin   +3 more
wiley   +1 more source

Recognition of Non-standard Base Pairs by Triplex-Forming Oligonucleotides Containing an Expanded Genetic Alphabet

Rusling D, Brazzill M, Ma R, Munn K, Prestifilippo L, Pickford A, Kim H, Chen C, Hoshika S, Benner S.   +9 more
europepmc   +1 more source

The oncogenic control of nucleotide synthesis. [PDF]

Oncogenesis
Vidal-Cruchez O, Ben-Sahra I.
europepmc   +1 more source

Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer. [PDF]

Cancer Res
Gebru MT, Hoffman TE, Boudreau A, Vu N, Han F, Wang P, Folk E, Wu X, Newton J, Foster-Duke KD, Gajda J, Villa S, Yang N, Sandoval CM, Grant C, Wildeboer SE, Buck WR, Hickson JA, Firestone AJ, Kort M, Bennett BD, Shotwell JB, Wilson NS, Stokoe D.   +23 more
europepmc   +1 more source

Expanding Peptide Chemical Space via Acid-Mediated Arginine Modification. [PDF]

Org Lett
Sihag P, Kwon M, Misra A, Raj M.
europepmc   +1 more source

Aqueous-Phase Multicomponent Reaction Mechanism for the Synthesis of Pyrido[2,3‑<i>d</i>]pyrimidines: A Theoretical Perspective. [PDF]

ACS Omega
Rufino VC, Amarante GW, Dos Santos HF.
europepmc   +1 more source

NuConf: a rotamer library for DNA and RNA and its implementation in the protein design software MUMBO. [PDF]

Sci Rep
Makarova MO, Stiebritz MT, Basturk D, Lemke B, Süss B, Muller YA.   +5 more
europepmc   +1 more source