Results 11 to 20 of about 43,355 (293)

Genetic Analysis of MEFV Gene Pyrin Domain in Patients With Behçet's Disease [PDF]

Mediators of Inflammation, 2006
Objectives. Behçet's disease (BD) is a systemic vasculitis with recurrent oral and genital ulcers and uveitis. MEFV gene, which is the main factor in familial Mediterranean fever (FMF), is also reported to be a susceptibility gene for BD.
Ahmet Dursun, Hatice Gul Durakbasi-Dursun, Ayse Gul Zamani, Zerrin Gülin Gulbahar, Recep Dursun, Cengiz Yakicier   +5 more
doaj   +8 more sources

A Novel Mutation in the Pyrin Domain of the NOD-like Receptor Family Pyrin Domain Containing Protein 3 in Muckle-Wells Syndrome

Chinese Medical Journal, 2017
Background: Cryopyrin-associated periodic syndrome (CAPS) is a group of rare, heterogeneous autoinflammatory disease characterized by interleukin (IL)-1β-mediated systemic inflammation and clinical symptoms involving skin, joints, central nervous system,
Jian Hu, Yun Zhu, Jian-Zhong Zhang, Rong-Guang Zhang, Hou-Min Li   +4 more
doaj   +3 more sources

Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome [PDF]

Frontiers in Immunology, 2018
The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-protein complex that can be activated by a variety of pathogen-associated molecular patterns or damage-associated molecular patterns.
Do-Wan Shim, Kwang-Ho Lee, Kwang-Ho Lee
doaj   +3 more sources

Dynamic disequilibrium-based pathogenicity model in mutated pyrin’s B30.2 domain—Casp1/p20 complex [PDF]

Journal of Genetic Engineering and Biotechnology, 2022
Background The B30.2 variants lead to most relevant severity forms of familial Mediterranean fever (FMF) manifestations. The B30.2 domain plays a key role in protein-protein interaction (PPI) of pyrin with other apoptosis proteins and in regulation the ...
Alaaeldin G. Fayez, Ghada Nour Eldeen, Waheba A. Zarouk, Khaled Hamed, Abeer Ramadan, Bardees M. Foda, Maha M. Kobesiy, Mai E. Zekrie, Randa S. Lotfy, Mona F. Sokkar, Hala T. El-Bassyouni   +10 more
doaj   +3 more sources

Three-dimensional Structure of the NLRP7 Pyrin Domain [PDF]

Journal of Biological Chemistry, 2010
Anderson S. Pinheiro, Martina Proell, Clarissa Eibl, Rebecca Page, Robert Schwarzenbacher, Wolfgang Peti   +5 more
openalex   +3 more sources

The PYRIN Domain in Signal Transduction [PDF]

Current Protein & Peptide Science, 2007
The Death Domain Fold superfamily of evolutionarily conserved protein-protein interaction domains consists of 4 subfamilies: the death domain, the death effector domain, the caspase recruitment domain, and the PYRIN domain. Interaction of Death Domain Fold containing proteins modulates the activity of several downstream effectors, such as caspases and ...
Christian Stehlik
openalex   +4 more sources

NLR family pyrin domain containing 6 (NLRP6; NALP6) [PDF]

Science-Business eXchange, 2011

openalex   +2 more sources

The Emerging Role of Colchicine to Inhibit NOD-like Receptor Family, Pyrin Domain Containing 3 Inflammasome and Interleukin-1β Expression in In Vitro Models. [PDF]

Biomolecules
Astiawati T, Rohman MS, Wihastuti T, Sujuti H, Endharti A, Sargowo D, Oceandy D, Lestari B, Triastuti E, Nugraha RA.   +9 more
europepmc   +3 more sources

[Latest Findings on NOD-Like Receptor Family Pyrin Domain Containing Protein 3 Inflammasome and Bone and Articular Diseases]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban, 2023
Wang JH, Zou SJ, Xie J, Zhou CC.
europepmc   +3 more sources

FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway. [PDF]

Exp Anim, 2023
Wei J, Yin J, Cui Y, Wang K, Hong M, Cui J.   +5 more
europepmc   +3 more sources