Results 201 to 210 of about 43,355 (293)

NLR family pyrin domain containing 12 (NLRP12; NALP12) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

The NLRP3 Inflammasome Regulates Orthodontic Tooth Movement

Orthodontics &Craniofacial Research, Volume 29, Issue 1, Page 134-143, February 2026.
ABSTRACT Objective The NLRP3 inflammasome is a damage sensor driving pyroptotic cell death during orthodontic tooth movement (OTM). Recent studies have revealed impaired one‐week OTM in mice lacking NLRP3. However, the relevance of NLRP3 during long‐term OTM remains unknown.
Lisa Latzko, Gerald Degenhart, Michael J. Blumer, Reinhard Gruber, Johannes Haybäck, Claudia Manzl, Adriano G. Crismani   +6 more
wiley   +1 more source

Structural insights into the atypical filament assembly of pyrin domain-containing IFI16. [PDF]

EMBO J
Garg A, Niedzialkowska E, Zhou JJ, Moh J, Egelman EH, Sohn J.   +5 more
europepmc   +1 more source

Uric acid promotes myocardial infarction injury via activating pyrin domain-containing 3 inflammasome and reactive oxygen species/transient receptor potential melastatin 2/Ca²⁺pathway. [PDF]

BMC Cardiovasc Disord, 2023
Wu H, Dai R, Wang M, Chen C.
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, Volume 16, Issue 1, Page 11-24, January 2026.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Mechanisms and Targeted Therapeutic Strategies in Sepsis-Induced Myocardial Dysfunction: The Role of NLRP3 Inflammasome-Mediated Inflammation

Journal of Inflammation Research
Yuan-Yuan Yu,1 Rong Wang,2 Guo-Qing Chen,3 Yu-Fang Gui,3 Juan Ma,3 Jin-Hai Ma,3 Shu-Jing Li3 1Department of Emergency Medical, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, 750000, People’s Republic of China; 2Department of Nuclear ...
Yu YY, Wang R, Chen GQ, Gui YF, Ma J, Ma JH, Li SJ   +6 more
doaj  

Influence of Pyroptosis Induced by NOD-Like Receptor Pyrin Domain-Containing 3 Inflammasomes on Viral Myocarditis in Children. [PDF]

Int J Gen Med
Huang H, Lou J, Chen W, Cheng X, Xing X, Huang S.   +5 more
europepmc   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan, Senlin Li, Shuai Liu, Hong Zhou, Yue Xu, Wenhui Li, Mengxuan Wang, Mengheng Wang, Mengzhu Zheng, Wenxi Shi, Xin Li, Yiting Feng, Ming Xiang   +12 more
wiley   +1 more source

Expression and correlation of the NOD-like receptor family, pyrin domain-containing 3 inflammasome and the silent information regulator 1 in patients with drug-resistant epilepsy

Qing Li, Zhenzhen Qu, Lijing Jia, Weiping Wang   +3 more
openalex   +1 more source

A Poxvirus-Encoded Pyrin Domain Protein Interacts with ASC-1 to Inhibit Host Inflammatory and Apoptotic Responses to Infection [PDF]

, 2006
James B. Johnston, John W. Barrett, Steven H. Nazarian, Megan Goodwin, Dan Ricciuto, Gen Wang, Grant McFadden   +6 more
openalex   +1 more source