Role of Long Intergenic Nonprotein-Coding RNA 00511 in Nod-Like Receptor Protein Pyrin Domain 3-Induced Chondrocyte Pyroptosis via the MicroRNA-9-5p/FUT1 Axis. [PDF]
Zhai T, Zhang Z, Hu X, He D, Feng W.
europepmc +1 more source
Interleukin-18 and the NLR family pyrin domain containing-3 inflammasome in adipose tissue are strongly associated with glucometabolic variables in a cohort of middle-aged men [PDF]
Sissel Åkra +6 more
openalex +1 more source
NLR family pyrin domain containing 1 (NLRP1; NALP1); NLRP3 (NALP3) [PDF]
openaire +1 more source
ABSTRACT Aim Under certain conditions, infection‐induced inflammation may activate reparative processes to form a hard tissue barrier against microbial invasion. Autophagy participates in odontogenic differentiation during inflammation in vitro, but its role in pulp repair remains unclear.
Peiling Hu +7 more
wiley +1 more source
Competitive adsorption of microRNA-532-3p by circular RNA SOD2 activates Thioredoxin Interacting Protein/NLR family pyrin domain containing 3 pathway and promotes pyroptosis of non-alcoholic fatty hepatocytes. [PDF]
Chen F +7 more
europepmc +1 more source
Proteome‐Guided Drug Target Discovery for Periodontitis
ABSTRACT Background and Objective Periodontitis is a chronic inflammatory disease driven by immune dysfunction and microbial imbalance. This study aims to identify circulating druggable proteins causally linked to the disease. Materials and Methods We integrated proteomics data from deCODE genetics with periodontitis genome‐wide association studies ...
Zoheir Alayash +8 more
wiley +1 more source
Given the absence of curative treatments for neurodegenerative diseases, early detection and therapeutic intervention are critical to slowing disease progression. The last decade has seen accumulating evidence for microRNA dysregulation in circulating extracellular vesicles (EVs); however, assessing reproducibility between studies remains challenging ...
Aliyah Zaman +2 more
wiley +1 more source
The multifaceted roles of ketones in physiology
Abstract The production of ketones, referred to as ketogenesis, plays an essential role in maintaining energy homeostasis during prolonged fasting/starvation, which primarily stems from its ability to serve as a fuel source to support neuronal ATP production, thereby limiting muscle wasting. Over the years, the field has come to appreciate that ketones
Seyed Amirhossein Tabatabaei Dakhili +3 more
wiley +1 more source
Objective Pulmonary fibrosis may develop in patients with severe clinical conditions, especially those with high inflammatory indicators. We aimed to investigate the 15‐month follow‐up clinical outcomes in patients with moderate‐to‐severe COVID‐19 pneumonia treated with colchicine and to evaluate its potential in preventing post‐COVID pulmonary ...
Gulhan Ayhan Albayrak +3 more
wiley +1 more source
Evaluation of the Effect of IL‐1 Antagonists on Pituitary Function
Background Familial Mediterranean fever (FMF) is a hereditary autoinflammatory disease frequently observed in populations along the Eastern Mediterranean coast, characterized by recurrent fever, abdominal pain, and joint inflammation. The disease results from mutations in the MEFV gene, which plays a critical role in regulating IL‐1β secretion ...
Fadime Aktas Koc +3 more
wiley +1 more source

