Results 21 to 30 of about 43,355 (293)

Vitamin D Status Modestly Regulates NOD-Like Receptor Family with a Pyrin Domain 3 Inflammasome and Interleukin Profiles among Arab Adults [PDF]

open access: goldInt J Mol Sci, 2023
Sobhy M. Yakout   +4 more
europepmc   +3 more sources

Mapping of POP1-binding Site on Pyrin Domain of ASC [PDF]

open access: hybridJournal of Biological Chemistry, 2008
Apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) is an essential adaptor protein in the formation of a multiprotein complex that activates procaspase-1. ASC is also known as a modulator of NF-kappaB activation pathways.
Thiagarajan Srimathi   +6 more
openalex   +4 more sources

NLRP3 inflammasome assembly is regulated by phosphorylation of the pyrin domain [PDF]

open access: greenJournal of Experimental Medicine, 2017
NLRP3 is a cytosolic pattern recognition receptor that senses microbes and endogenous danger signals. Upon activation, NLRP3 forms an inflammasome with the adapter ASC, resulting in caspase-1 activation, release of proinflammatory cytokines and cell death.
Andrea Stutz   +9 more
  +8 more sources

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]

open access: yes, 2012
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen   +5 more
core   +19 more sources

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