Results 101 to 110 of about 11,970 (271)

Hamman's crunch—A pathognomonic sign of pneumomediastinum

Equine Veterinary Education, EarlyView.
Summary Pneumomediastinum, particularly spontaneous pneumomediastinum, is uncommon and presents a diagnostic challenge. In human medicine, auscultation of Hamman's crunch, a crepitant, crunching noise, audible over the cardiac region in synchrony with the heartbeat, is considered pathognomonic for pneumomediastinum.
S. McCullagh, C. R. Daniel, J. A. Keen, N. J. Parkinson, B. C. McGorum   +4 more
wiley   +1 more source

Final Analysis of the Phase 1/2 Trial of Valoctocogene Roxaparvovec for Severe Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Valoctocogene roxaparvovec is an adeno‐associated virus vector serotype 5 (AAV5)‐mediated gene therapy for severe haemophilia A (HA). Aim Report the final safety and efficacy results of the phase 1/2 trial of valoctocogene roxaparvovec. Methods An open‐label phase 1/2 trial (NCT02576795) enrolled adult males with severe HA (factor
Priyanka Raheja, Savita Rangarajan, Will Lester, Bella Madan, Glenn F. Pierce, Emily Symington, Carolyn Millar, Dane Osmond, Mingjin Li, Konstantia‐Maria Chavele   +9 more
wiley   +1 more source

Italian Patients Journey for Gene Therapy in Haemophilia A

Haemophilia, EarlyView.
ABSTRACT Introduction Gene therapy (GT) provides sustained FVIII levels without repeated infusions in Hemophilia A (HA) patients thus overcoming a major limitation of replacement therapy. However, issues remain e.g., patient selection criteria, duration and variability of transgene expression, quality of life and long‐term safety.
Giovanni Di Minno, Gaia Spadarella, Alessandra Borchiellini, Anna Borrelli, Andrea Buzzi, Giancarlo Castaman, Michele Cecchi, Raimondo De Cristofaro, Vincenzo La Mura, Angelo Lupi, Giuseppe Malcangi, Maria Elisa Mancuso, Maria Francesca Mansueto, Cristina Santoro, Rita Carlotta Santoro, Luigi Piero Solimeno, Annarita Tagliaferri, Ezio Zanon, Isabella Garagiola, Flora Peyvandi   +19 more
wiley   +1 more source

Behavioral responses to pyrogen in cold-stressed and starved newborn rabbits

, 1981
Starvation for 2 days and a chronic mild cold stress prevented the rises in body temperature that normally occur in newborn rabbits that have been injected with pyrogen (Piromen, 5 mg/kg).
N. Kleitman, E. Satinoff
core   +1 more source

From Sprinters to Marathoners: Rethinking Therapeutic Speed and Disease Modification in Atopic Dermatitis

Allergy, EarlyView.
Thomas Bieber, Felix Lauffer
wiley   +1 more source

Optimising hyperacute intracerebral haemorrhage management: factors influencing timely intervention

Internal Medicine Journal, EarlyView.
Abstract Background Bundled‐care protocols, which include rapid lowering of blood pressure, have improved functional outcomes in patients with intracranial haemorrhage (ICH). Specifically, the intensive blood pressure reduction in acute cerebral hemmorhage trail (INTERACT) 3 trial aimed to achieve rapid lowering of systolic blood pressure (SBP) to 140 ...
Edmund Proper, Thanh Phan, Henry Ma, Michael Valente   +3 more
wiley   +1 more source

Pyrogen.

The Homoeopathic physician
Citation: 'pyrogen' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13626 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +3 more sources

Propranolol and pyrogen effects of shivering and nonshivering thermogenesis in rats

, 1976
Injection of bacterial endotoxin (Piromen) into unanesthetized rats elicited increases in shivering and nonshivering thermogenesis as well as in colonic temperature.
GE Hanes, BA Horwitz
core   +1 more source

Antimicrobial prescribing guidelines for feedlot cattle

Australian Veterinary Journal, EarlyView.
P Cusack, T Batterham, SW Page, GF Browning, JM Norris   +4 more
wiley   +1 more source

Dupilumab treatment in children aged 6 months to 5 years with severe atopic dermatitis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
The results of this French Early Access Program were consistent with those reported in dupilumab randomized clinical trials in children aged 6 months–5 years with moderate‐to‐severe AD. This research offers insights into the practical use of dupilumab in routine clinical practice.
Audrey Lasek, Nathalia Bellon, Stéphanie Mallet, Hélène Aubert, Carine Vera, Lamia Achour, Claire Thénié, Randy Prescilla, Claire Abasq‐Thomas, Sébastien Barbarot   +9 more
wiley   +1 more source