Results 81 to 90 of about 11,970 (271)
, 1960 To investigate more accurately the effect of pyrogen from E. coli on liver metabolism, its influence on mitochondrial fractions and on the activity of succinic acid dehydrogenase in this fraction has been studied.
Anna Desperak-Naciazek, Jan Venulet
core +1 more source
Allergy, EarlyView.Ligelizumab re‐treatment in CSU patients showed sustained efficacy and tolerability. Over 50% achieved symptom control (UAS7 ≤ 6) by Week 12; benefits maintained through Week 52. No new safety signals observed; aligns with prior PEARL trial outcomes. CSU, chronic spontaneous urticaria; mg, milligram; q4w, every 4 weeks; UAS, urticaria activity score ...
Ana M. Gimenez‐Arnau +22 more
wiley +1 more source
A PEG-Based Hydrogel for Effective Wound Care Management
Cell Transplantation, 2018 It is extremely challenging to achieve strong adhesion in soft tissues while minimizing toxicity, tissue damage, and other side effects caused by wound sealing materials.
Sen-Lu Chen +5 more
doaj +1 more source
ATTRIBUTES OF BACTERIAL ENDOTOXIN TEST (BET) AND ITS COMPARISON WITH RABBIT PYROGEN TEST.
, 2019 Presence of pyrogen (mostly endotoxins) in therapeutics can cause harmful symptoms in patients, so it is mandatory to test the presence of pyrogens in different therapeutics including biologicals. Now-a-days the use of animals is not the preferred method
Shruti Samlet , Kedar Shedage +2 more
core +1 more source
Allergy, EarlyView.ABSTRACT Hereditary angioedema (HAE) with C1 inhibitor deficiency is a rare disease characterized by unpredictable episodes of tissue swelling (angioedema), which, in most cases, occur first under the age of 18 years, and entail a significant burden of disease not only for the patients but also for their families.
Henriette Farkas +128 more
wiley +1 more source
Platonin, a Cyanine Photosensitizing Dye, Inhibits Pyrogen Release and Results in Antipyresis
Journal of Pharmacological Sciences, 2003 : Intravenous injection of the supernatant fluids from human peripheral blood mononuclear cells (PBMC) incubated with lipopolysaccharide (LPS) caused fever in rabbits.
Jie-Jen Lee +4 more
doaj +1 more source
Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
Allergy, EarlyView.This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Cytokines as Endogenous Pyrogens [PDF]
The Journal of Infectious Diseases, 1999 Cytokines are pleiotropic molecules mediating several pathologic processes. Long before the discovery of cytokines as immune system growth factors or as bone marrow stimulants, investigators learned a great deal about cytokines when they studied them as the endogenous mediators of fever.
openaire +2 more sources
Detection of pyrogen levels in the ordered oligonucleotides using monocyte activation test (MAT).
, 2013 Detection of pyrogen levels in the ordered oligonucleotides using monocyte activation test (MAT).
Tatjana Michel (436296) +4 more
core +1 more source
Preparation and evaluation of injectable dosage form for Pemetrexed-monoclonal antibody conjugate
Iraqi Journal of Pharmaceutical SciencesAntibody-drug conjugates (ADCs), a powerful type of pharmaceutical medications that combine immunotherapy and chemotherapy. Pemetrexed is a multitarget antifolate agent that inhibit essential enzymes involve in purine and pyrimidine synthesis, therefore
Faten Q. Ibraheem +2 more
doaj +1 more source