Results 61 to 70 of about 21,408 (184)

Molecular targeting of DNA metabolism by brown algae metabolites in Mycobacterium chelonae: computational analysis via DFT and MD simulations

open access: yesScientific Reports
Mycobacterium chelonae, a member of the rapidly growing mycobacteria, has been linked to a variety of infections, including skin and soft tissue infections, pulmonary disease, and disseminated infections in immunocompromised people.
Abdullah R. Alanzi   +2 more
doaj   +1 more source

Inactivation of yeast inorganic pyrophosphatase by organic solvents

open access: yesAnais da Academia Brasileira de Ciências, 2004
A number of application for enzymes in organic solvents have been developed in chemical processing, food related conversions and analyses. The only unsolved problem related to nonaqueous enzymology is the notion that enzymes in organic solvent are mostly
Rodrigo Grazinoli-Garrido   +1 more
doaj   +1 more source

Regulation of neurite growth by inorganic pyrophosphatase 1 via JNK dephosphorylation. [PDF]

open access: yesPLoS ONE, 2013
Neural cell differentiation during development is controlled by multiple signaling pathways, in which protein phosphorylation and dephosphorylation play an important role.
Yu Tezuka   +5 more
doaj   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima   +6 more
wiley   +1 more source

Histochemical Studies on Pyrophosphatase in Urological Field Report I. Activity of Pyrophosphatase in Normal Rabbits [PDF]

open access: yes, 1958
The activity of pyrophosphatase was not di s tinctly known in our urological field because we had no methods for its histological demonstration. Last year, Maeda successed in it.
鮫島, 博
core  

Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1

open access: yesNature Communications, 2018
Ecto-nucleotide pyrophosphatase phosphodiesterase 1 (ENPP1) is a type II transmembrane glycoprotein that hydrolyzes both ATP and cGAMP. Here the authors present the crystal structures of the extracellular domain of mouse ENPP1 in complex with 3′3′-cGAMP ...
Kazuki Kato   +8 more
doaj   +1 more source

Proteo‐transcriptomic insights into the venom composition of the ectoparasitoid Eupelmus urozonus

open access: yesPest Management Science, EarlyView.
Integrated venom‐gland transcriptomics and venom proteomics of Eupelmus urozonus identified 316 venom proteins, including 75 secreted candidates, revealing diverse hydrolases, proteases/inhibitors and many uncharacterized effectors. Abstract BACKGROUND Ectoparasitoid venoms are ‘cocktails’ of bioactive molecules injected during oviposition to paralyze ...
Federica De Stefano   +7 more
wiley   +1 more source

Genetic suppressor screen identifies Tgp1 (glycerophosphocholine transporter), Kcs1 (IP6 kinase), and Plc1 (phospholipase C) as determinants of inositol pyrophosphate toxicosis in fission yeast

open access: yesmBio
The inositol pyrophosphate signaling molecule 1,5-IP8 is an agonist of RNA 3'-processing and transcription termination in fission yeast that regulates the expression of phosphate acquisition genes pho1, pho84, and tgp1.
Lauren Bednor   +4 more
doaj   +1 more source

LsFAMeT and LsJHAMT coordinate JH biosynthesis to regulate fecundity in Laodelphax striatellus

open access: yesInsect Science, EarlyView.
The small brown planthopper (SBPH), Laodelphax striatellus, can trigger large‐scale outbreaks when encountering suitable habitats during migration due to their strong reproductive ability. This study investigated the role of juvenile hormone (JH) in regulating SBPH reproduction.
Yan Guo   +3 more
wiley   +1 more source

INTERACTIONS OF CALCIUM AND MAGNESIUM WITH THE MITOCHONDRIAL INORGANIC PYROPHOSPHATASE FROM SACCHAROMYCES-CEREVISIAE

open access: yes, 2015
The activity of the mitochondrial inorganic pyrophosphatase from Saccharomyces cerevisiae was measured in the presence of increasing concentrations of magnesium and calcium.
PARDO, JP   +3 more
core   +1 more source

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