Results 51 to 60 of about 3,409 (207)

Two independent evolutionary routes to Na+/H+ cotransport function in membrane pyrophosphatases. [PDF]

, 2022
Membrane-bound pyrophosphatases (mPPases) hydrolyze pyrophosphate (PPi) to transport H(+), Na(+) or both and help organisms to cope with stress conditions, such as high salinity or limiting nutrients.
Heidi H. Luoto, Reijo Lahti, Anssi M. Malinen, Erika Nordbo, Alexander A. Baykov   +4 more
core   +1 more source

H+-pyrophosphatases enhance low nitrogen stress tolerance in transgenic Arabidopsis and wheat by interacting with a receptor-like protein kinase

Frontiers in Plant Science, 2023
IntroductionNitrogen is a major abiotic stress that affects plant productivity. Previous studies have shown that plant H+-pyrophosphatases (H+-PPases) enhance plant resistance to low nitrogen stress.
Huijuan Zhang, Huijuan Zhang, Ming Chen, Chengjie Xu, Chengjie Xu, Rongbang Liu, Wensi Tang, Kai Chen, Yongbin Zhou, Zhaoshi Xu, Jun Chen, Youzhi Ma, Weiguo Chen, Daizhen Sun, Hua Fan   +14 more
doaj   +1 more source

Functional Specialization of Respiratory and Olfactory Mucus Revealed by Proteomic Profiling

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Mucus overlies the nasal mucosa in the respiratory and olfactory regions, which perform distinct physiological functions. However, proteomic differences between respiratory mucosa (RM) and olfactory cleft (OC) mucus remain unclear.
Anna Kristina Hernandez, Karoline Lantzsch, Romain Topalian, Nadine Gunder, Philipp Hubel, Katharina Schindowski, Jens Pfannstiel, Thomas Hummel   +7 more
wiley   +1 more source

In vivo Production of Soluble Inorganic Pyrophosphatases in Two Strains of <i>Vibrio cholerae </i>

, 1970
The in vivo production of soluble inorganic pyrophosphatases (PPases) was investigated in two strains, namely, Vibrio cholerae EM 004 (environmental strain) and Vibrio cholerae O1 757 (ATCC strain). V.
Taslima Taher Lina, Mohammad Ilias
core   +1 more source

H⁺-Translocating Membrane-Bound Pyrophosphatase from Rhodospirillum rubrum Fuels Escherichia coli Cells via an Alternative Pathway for Energy Generation

Microorganisms, 2023
Inorganic pyrophosphatases (PPases) catalyze an essential reaction, namely, the hydrolysis of PPi, which is formed in large quantities as a side product of numerous cellular reactions.
Evgeniya A. Malykh, Liubov I. Golubeva, Ekaterina S. Kovaleva, Mikhail S. Shupletsov, Elena V. Rodina, Sergey V. Mashko, Nataliya V. Stoynova   +6 more
doaj   +1 more source

Genetic and Population Analyses Implicate Thyroid‐Related Regulation of RNF144B in Chondrocalcinosis

Arthritis &Rheumatology, EarlyView.
Objective Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5% to 15% of the general population and has recently been identified as an osteoarthritis risk factor. However, its biologic pathways remain unclear.
Yahong Wu, Yanning Xu, Paul C. Okoro, Sirine Saafi, Jard de Vries, Xiaoyi Qi, Edwin H. G. Oei, Sita Bierma‐Zeinstra, Trudy Voortman, David Felson, Joyce B. J. van Meurs, Layal Chaker, J. Mark Wilkinson, Michelle S. Yau, Jessica Bertrand, Cindy G. Boer   +15 more
wiley   +1 more source

Uncatalyzed Guanosine Phosphorylation under Potentially Prebiotic Conditions

Chemistry – A European Journal, EarlyView.
Pyrophosphate acts as phosphorylating agent of guanosine under simple wet‐dry cycles without condensing agent and inorganic catalysts to afford cyclic guanosine monophosphate derivatives useful for oligomerization in prebiotic processes. ABSTRACT The phosphorylation of nucleosides and their subsequent polymerization are key issues in the study of the ...
Martina Proietti, Bruno Mattia Bizzarri, Elisa De Marchi, Alessandra Giorgi, Raffaele Saladino, Giovanna Costanzo   +5 more
wiley   +1 more source

Different from bone: Tooth formation and enameloid mineralization are not affected by reduced dietary phosphorus intake

Developmental Dynamics, EarlyView.
Abstract Background Vertebrates rely on phosphorus intake for skeletal mineralization. In humans, hypomineralized teeth associated with rickets, hypophosphatemia, hypophosphatasia, or idiopathic molar‐incisor‐hypomineralization pose significant problems.
S. Cotti, A. Huysseune, I. A. K. Fiedler, B. Busse, C. Di Biagio, M. Rücklin, F. Marone, A. Forlino, P. E. Witten   +8 more
wiley   +1 more source

The structural basis for pyrophosphatase catalysis [PDF]

Structure, 1996
Soluble inorganic pyrophosphatase (PPase), an essential enzyme central to phosphorus metabolism, catalyzes the hydrolysis of the phosphoanhydride bond in inorganic pyrophosphate. Catalysis requires divalent metal ions which affect the apparent pKas of the essential general acid and base on the enzyme, and the pKa of the substrate.
Heikinheimo, Pirkko, Lehtonen, Jukka, Baykov, Alexander, Lahti, Reijo, Cooperman, Barry S, Goldman, Adrian   +5 more
openaire   +2 more sources

Cell stress by phosphate of two protozoa tetrahymena thermophila and tetrahymena pyriformis [PDF]

, 2017
Phosphorus is one of the bioelements most needed as a compound cell by living organisms. Phosphorus is involved in several pathologies: in human with bone and kidney diseases, in mammals with metabolism disorder (glucose, insulin¿¿¿), in ...
Soikri, A., El Khalfi, B., Papa Daouda, Mar, Serrano, Aurelio, Pérez-Castiñeira, J. R., Serrano Delgado, Aurelio, Pérez Castiñeira, José Román, Abdelaziz Soukri, Soukri, Abdelaziz, Jose Roman Perez-Castiñeira, Elkhalfi, Bouchra, Aurelio Serrano, Papa Daouda Mar, Papa daoda, Mar, Bouchra El Khalfi   +14 more
core   +2 more sources