Results 211 to 220 of about 195,629 (388)

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Multiple facets of H+-pyrophosphatase and related enzymes

open access: yesFrontiers in Plant Science, 2016
Ali Ferjani, Masayoshi Maeshima
doaj   +1 more source

Systematic characterization and functional analysis of <i>trans</i>-prenyltransferases in <i>Curcuma wenyujin</i>. [PDF]

open access: yesFront Plant Sci
Wang Q   +12 more
europepmc   +1 more source

Molecular Identification and Functional Characterization of the Human Colonic Thiamine Pyrophosphate Transporter [PDF]

open access: hybrid, 2013
Svetlana M. Nabokina   +5 more
openalex   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

open access: yesCell Proliferation, EarlyView.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie   +8 more
wiley   +1 more source

Technetium-99m-labeled pyrophosphate uptake in the rectum of a patient with wild-type transthyretin cardiac amyloidosis. [PDF]

open access: yesRadiol Case Rep
Takahashi K   +8 more
europepmc   +1 more source

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