Results 201 to 210 of about 77,046 (386)

Burkholderia cenocepacia induces pyroptosis in macrophages.

, 2012
Roberto Rosales-Reyes, Daniel Aubert, Jennifer S. Tolman, Amal O. Amer, Miguel A. Valvano   +4 more
openalex   +1 more source

Atg7 Deficiency Intensifies Inflammasome Activation and Pyroptosis in Pseudomonas Sepsis [PDF]

, 2017
Qinqin Pu, Changpei Gan, Rongpeng Li, Yi Li, Shirui Tan, Xuefeng Li, Yuquan Wei, Lefu Lan, Xin Deng, Haihua Liang, Feng Ma, Min Wu   +11 more
openalex   +1 more source

Combating cancer immunotherapy resistance: a nano‐medicine perspective

Cancer Communications, EarlyView.
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong, Xintong Xie, Juan Wu, Xiangyu Wang, Wenxiang Zhang, Shuowen Wang, Daria Valerievna Abbasova, Yi Fang, Hongnan Jiang, Jidong Gao, Jing Wang   +10 more
wiley   +1 more source

145 Pyroptosis and HIV-Induced CD4 T Cell Death

, 2012
Gilad Doitsh, Orlando Zepeda, Nicole Galloway, Isa Arias, Warner C. Greene   +4 more
openalex   +1 more source

Erratum: Corrigendum: Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection [PDF]

, 2017
Gilad Doitsh, Nicole Galloway, Xin Geng, Zhiyuan Yang, Kathryn M. Monroe, Orlando Zepeda, Peter Hunt, Hiroyu Hatano, Stefanie Sowinski, Isa Muñoz-Arias, Warner C. Greene   +10 more
openalex   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

Identification of a pyroptosis-related prognostic model for colorectal cancer and validation of the core gene SPTBN5

Discover Oncology
Background Pyroptosis, an emerging type of programmed cell death. The mechanisms of pyroptosis mainly include inflammasome-activated pyroptosis and non-inflammasome-activated pyroptosis. Multiple prognostic scoring systems that utilize pyroptosis-related
Guangyao Li, Pingyu Wang, Xiangnan Feng, Yongxiang Li   +3 more
doaj   +1 more source

TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis

, 2013
Sanna Nyström, Daniel J. Antoine, Peter Lundbäck, John G. Lock, Andreia Nita, Kari Högstrand, Alf Grandien, Helena Erlandsson-Harris, Jan Andersson, Steven E. Applequist   +9 more
openalex   +2 more sources

Identification of a New Interesting BAG3 Modulator Able to Disrupt Cancer‐Related Pathways

ChemMedChem, Accepted Article.
Continuing our research aimed at discovering new BAG3 modulators as attractive anticancer drug candidates, we performed a screening campaign on an in‐house library, including compounds featuring a large variety of scaffolds. The obtained results induced us to focus on the triazole moiety and, following a stepwise structural refinement of the scaffold ...
Dafne Ruggiero, Eleonora Boccia, Emis Ingenito, Vincenzo Vestuto, Gilda D’Urso, Alessandra Capuano, Agostino Casapullo, Stefania Terracciano, Giuseppe Bifulco, Gianluigi Lauro, Ines Bruno   +10 more
wiley   +1 more source

Nanoparticle-mediated cell pyroptosis: a new therapeutic strategy for inflammatory diseases and cancer

Journal of Nanobiotechnology
Pyroptosis, a lytic form of cell death mediated by the gasdermin family, is characterized by cell swelling and membrane rupture. Inducing pyroptosis in cancer cells can enhance antitumor immune responses and is a promising strategy for cancer therapy ...
Lin Zhao, Haipeng Cheng, Zhongyi Tong, Jing Cai   +3 more
doaj   +1 more source