NLRP3/ASC-mediated alveolar macrophage pyroptosis enhances HMGB1 secretion in acute lung injury induced by cardiopulmonary bypass [PDF]
Lei Hou+10 more
openalex +1 more source
FDG PET/CT imaging and circulating biomarkers of inflammation in desmoplakin cardiomyopathy
Abstract Aims Inflammation has been implicated in the pathogenesis of desmoplakin (DSP) cardiomyopathy, and retrospective studies have described abnormal myocardial fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) findings in symptomatic patients eventually diagnosed with DSP cardiomyopathy.
Sanjay Divakaran+10 more
wiley +1 more source
Single-walled carbon-nanohorns improve biocompatibility over nanotubes by triggering less protein-initiated pyroptosis and apoptosis in macrophages [PDF]
Bing He+12 more
openalex +1 more source
Inhibiting the NLRP3 Inflammasome With MCC950 Ameliorates Isoflurane-Induced Pyroptosis and Cognitive Impairment in Aged Mice [PDF]
Yunxia Fan+6 more
openalex +1 more source
Pyroptosis-induced inflammation and tissue damage.
Swathy O. Vasudevan+2 more
semanticscholar +1 more source
Abstract Aims Heart failure (HF) is an important public health problem worldwide, and programmed cell death (PCD) plays a crucial role in its pathologic process. This study aims to identify the hub genes associated with HF through PCD in order to better understand the pathogenesis of HF and improve its diagnosis and treatment.
Hua‐jing Yuan+6 more
wiley +1 more source
Pyroptosis, a double-edged sword during pathogen infection: a review. [PDF]
Zhang Y+8 more
europepmc +1 more source
Sphingosine-1-phosphate Receptor 2 Signaling Promotes Caspase-11–dependent Macrophage Pyroptosis and Worsens Escherichia coli Sepsis Outcome [PDF]
Fang Song+8 more
openalex +1 more source
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu+5 more
wiley +1 more source
Differences in macrophage pyroptosis and polarization induced by nano-/micro-calcium oxalate crystals. [PDF]
Tong XY, Nong WJ, Tan RM, Ouyang JM.
europepmc +1 more source