Results 311 to 320 of about 77,046 (386)

Methane alleviates sepsis-induced injury by inhibiting pyroptosis and apoptosis: in vivo and in vitro experiments

, 2019
Zeyu Li, Yifan Jia, Yang Feng, Ruixia Cui, Runchen Miao, Xing Zhang, Kai Qu, Chang Liu, Jingyao Zhang   +8 more
openalex   +1 more source

Research Advances of the Autophagy‐Regulated Radiosensitivity

Cell Proliferation, EarlyView.
Autophagy plays a dual role in regulating cellular radiosensitivity in radiotherapy (RT). We discuss the mechanisms by which autophagy promotes survival and growthsuppression by modulating radiosensitivity. It also outlines some frontier autophagy‐targeted radiotherapies. ABSTRACT Autophagy is an evolutionarily conserved process of cell self‐catabolism
Hanyue Liu, Yanlan Xiao, Chuhao Dai, Keyu Chen, Xinyi Xu, Jianming Cai, Xuguang Hu, Jiaming Guo   +7 more
wiley   +1 more source

Cucurbitacin B induces oral squamous cell carcinomapyroptosis via GSDME and inhibits tumour growth. [PDF]

Transl Oncol
Chen X, Yang M, Zhang H, Wang Y, Yan W, Cheng C, Guo R, Chai J, Zheng Y, Zhang F.   +9 more
europepmc   +1 more source

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

Cell Proliferation, EarlyView.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su, Yanlin Li, Zihao Zhou, Bing Feng, Haiming Chen, Guangjuan Zheng   +5 more
wiley   +1 more source

Aloe vera-derived extracellular vesicle-like particles suppress pancreatic carcinoma progression through triggering pyroptosis via ROS-GSDMD/E signaling pathway. [PDF]

Chin Med
Shen J, Wei T, Li M, Jiang Y, Zhang J, Qi Y, Chen C, Li X, Huang P, Qu J.   +9 more
europepmc   +1 more source

Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases

Cell Proliferation, EarlyView.
HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang, Yue‐Yue Wang, Ri Wen, Tie‐Ning Zhang, Ni Yang   +4 more
wiley   +1 more source

Bladder cancer biomarker analysis and drugtarget prediction based on pyroptosis-related genes. [PDF]

Discov Oncol
Li P, Yang X, Liu Q, Zhang H, Luo Z.
europepmc   +1 more source

Faculty Opinions recommendation of High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis.

, 2019
Martine Bassilana
openalex   +1 more source

Single‐Nucleus Transcriptomics Uncovers Xaf1‐Driven PANoptosis as a Therapeutic Target in Aminoglycoside‐Induced Hearing Loss

Cell Proliferation, EarlyView.
Neomycin induces increased expression of Xaf1 in cochlear HCs, triggering PANoptosis, which encompasses pyroptosis, apoptosis and necroptosis (left). Targeted Xaf1 knockdown in HCs through gene therapy can significantly inhibit the occurrence of PANoptosis in HCs (right).
Xinlin Wang, Hairong Xiao, Jiheng Wu, Yanqin Lin, Yiheng Ao, Zixuan Ye, Xin Tan, Fanliang Kong, Xin Chen, Renjie Chai, Shasha Zhang   +10 more
wiley   +1 more source

Killing hepatocellular carcinoma in the NAFLD/NASH stage: a comprehensive perspective on targeting regulated cell death. [PDF]

Cell Death Discov
Xi J, Lei S, Chen J, Liu J, Shan C, Sun X, Zheng Q, Shi X.   +7 more
europepmc   +1 more source