Results 331 to 340 of about 77,046 (386)

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Evaluation of pyroptosis-associated genes in endometrial cancer utilizing a 101-combination machine learning framework and multi-omics data. [PDF]

Front Med (Lausanne)
Huang LJ, Liu C, Chen L, Tang M, Zhan ST, Chen F, Teng AY, Zhou LN, Sang WL, Yang Y.   +9 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Dual function of Gasdermin E: pyroptosis-mediated pan-cancer suppression versus HCC-specific oncogenic activity. [PDF]

Front Immunol
Kahaer G, Pan S, Yang C, Xie W, Lu Y.
europepmc   +1 more source

Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction

Neurogastroenterology &Motility, EarlyView.
Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley   +1 more source

ZC3H13 Promotes NSUN4-Mediated Chondrocyte Mitochondrial Dysfunction and Pyroptosis in Temporomandibular Joint Osteoarthritis. [PDF]

Cartilage
Chen Y, Ren H.
europepmc   +1 more source

Nitrate Prevents Sjögren's Disease by Modulating T Helper Cells via NF‐κB Pathway Suppression

Oral Diseases, EarlyView.
ABSTRACT Objective Sjögren's disease (SjD) is a chronic autoimmune disease characterized by abnormal T helper (Th) cell distribution in the salivary glands (SGs). Although nitrate can regulate immune responses and preserve SGs function, its preventive effects on SjD remain unexplored.
Conglin Du, Zi Yang, Yang Yang, Chunmei Zhang, Hideaki Kagami, Xianqi Li, Liang Hu, Junji Xu, Jian Zhou   +8 more
wiley   +1 more source

Unveiling PANoptosis in Acute Kidney Injury: An Integrative Multi-Dimensional Approach to Identify Key Biomarkers. [PDF]

J Inflamm Res
Wang N, Zhang L, Xu Z, Xu Q, Lu Y, Niu P, Yan L, Wang L, Cao H, Shao F.   +9 more
europepmc   +1 more source

Lesion Formation in Cardiac Pulsed‐Field Ablation: Acute to Chronic Cellular Level Changes

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT As pulsed‐field ablation (PFA) emerges as a promising therapy for atrial arrhythmias, an understanding of the cellular injury to cardiac tissue is critical to evaluating and interpreting results for each PFA system. This review aims to detail the mechanism of cell death for PFA, compare the cell death mechanism to thermal ablation modalities ...
Kara Garrott, Savannah Bifulco, David Ramirez, Brendan Koop   +3 more
wiley   +1 more source

RBPMS2 can inhibit the NLRP3 / caspase-1 / GSDMD signaling pathway to resist pyroptosis in gastric cancer cells. [PDF]

Sci Rep
Zhang N, Yan L, Cao H, Zhang N, Zhang T, Guan S, Liu Q.   +6 more
europepmc   +1 more source