Results 211 to 220 of about 132,748 (328)

Design, Synthesis, and Evaluation of Selective Ubiquitin-Specific Protease 11 (USP11) Inhibitors. [PDF]

ACS Omega
Hassan MA, Dekker LV, Stocks MJ, Dreveny I.   +3 more
europepmc   +1 more source

Organic Transistor‐Based Neuromorphic Electronics and Their Recent Applications

Small Methods, EarlyView.
This review highlights recent progress in organic neuromorphic electronics, showing how organic semiconductors enable synaptic and neuronal functions with low power, mechanical flexibility, and biocompatibility. By bridging materials, devices, and systems, organic platforms are accelerating brain‐inspired computing toward applications in artificial ...
Ziru Wang, Feng Yan
wiley   +1 more source

Small molecule-mediated spatial targeting of mitochondria and the Golgi apparatus in cancer cells. [PDF]

RSC Med Chem
Kumar P, Sahu A, Mishra T, Basu S.
europepmc   +1 more source

Metallic Axial Asymmetry in Dome‐Like Iron Porphyrins Boosts Advanced Oxidation Processes: Implication of Allosteric Effect of Heme Peroxidases

Small Structures, EarlyView.
A structure–activity relationship between dome‐deformation‐induced metallic axial asymmetry and catalytic efficiency in iron porphyrins was established, providing a molecular blueprint for designing high‐performance enzyme‐mimetic catalysts. The remarkable catalytic activity of heme enzymes originates from distinctive allosteric effects mediated by ...
Junhao Gao, Qiuhua Liu, Yusheng Zhang, Zhihong Fang, Wenping Guo, Zhenfang Zhang, Lei Bao, Tianyi Ma, Zaichun Zhou   +8 more
wiley   +1 more source

Merging Pyrrole with Boron into Versatile Di(2-pyrryl)borane Building Blocks: π-Extension, Polymerization, and Coordination. [PDF]

Angew Chem Int Ed Engl
Göbel D, Helbig A, Friedrich A, Bachmann J, Buckel M, Chorbacher J, Helten H.   +6 more
europepmc   +1 more source

Transcriptional Reinforcement of the HER2–RAS Network in HER2‐Positive Gastric Cancer: The RUNX–SOS1 Axis in Context

Cancer Science, EarlyView.
RUNX‐dependent transcriptional control of SOS1 reinforces HER2–RAS signaling and may attenuate responses to HER2‐targeted therapies in HER2‐positive gastric cancer. ABSTRACT HER2‐positive gastric cancer represents a distinct molecular subtype characterized by chromosomal instability, variable HER2 amplification, and substantial intratumoral ...
Tatsuya Masuda, Takayoshi Watanabe, Toshinori Ozaki, Yasuhiko Kamikubo   +3 more
wiley   +1 more source

Hepatic Sinusoidal Obstruction Syndrome Induced by Pyrrolizidine Alkaloids from <i>Gynura segetum</i>: Mechanisms and Therapeutic Advances. [PDF]

Molecules
Zhou Z, Yang D, Chu T, Zheng D, Zhang K, Liang S, Yang L, Yang Y, Ma W.   +8 more
europepmc   +1 more source

Pyrrol, verborgenes [PDF]

, 2019
openaire   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Lotusin A: a novel pyrrole terpenoid hydrid from lotus roots (<i>Nelumbo nucifera</i> Gaertn.). [PDF]

RSC Adv
Tran LVH, Vo HC, Hoang Long T, La VH, Le QT, Nguyen MC, Le DT, Nguyen TDL, Phan TT, Thi Thuy Duong N, Ton That Q, Tran L, Le MT, Thai KM, Hoang LT, Tran HNK.   +15 more
europepmc   +1 more source