Results 181 to 190 of about 17,074 (296)

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

A Modular Synthesis of Isoindole/Indolizine Hybrids via the 1,3‐Dipolar Cycloaddition of Pyridine‐Based Mesoionics with Benzyne

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
An approach to prepare pyrido[2,1‐a]isoindoles via the cycloaddition of pyridine‐based 1,3‐dipoles and benzyne is described, offering modular access to a range of substituted products by systematic tuning of the dipole. A modular strategy for the synthesis of fused indolizine/isoindole hybrids, pyrido[2,1‐α]isoindoles, via cycloaddition of pyridine ...
Samira Taghizadeh Nodehi   +2 more
wiley   +1 more source

Nickelaelectro-Catalyzed C─H Activation to β-Arylated Pyrroles via Multiple Dehydrogenation. [PDF]

open access: yesAngew Chem Int Ed Engl
Okamoto K   +6 more
europepmc   +1 more source

Gold(I)‐Mediated Reactivity of Allenes With Mesoionic Nucleophiles: A Computational Exploration

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
The regioselective gold(I)‐mediated reactivity of allenes with mesoionic nucleophiles has been evaluated through computational analysis of the mechanisms involved. Instead of typical (3 + 2) pathways, sydnones and münchnones favour the formal (3 + 3) cyclizations affording substituted dihydropyridines.
Eduardo Garcia‐Padilla, Feliu Maseras
wiley   +1 more source

Divergent photochemical ring-replacement of isoxazoles. [PDF]

open access: yesNat Commun
Xu Y   +5 more
europepmc   +1 more source

Remarkable Formation of Indene Derivatives Upon Friedel–Crafts Acylation Reactions

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This shows indene derivatives. Under the reaction conditions of a Friedel–Crafts acylation, alkyl benzenes underwent an unprecedented cyclopentannulation furnishing indene derivatives. Alkylbenzene derivatives react with two equivalents of pivaloyl chloride (PivCl) in the presence of aluminum trichloride under formation of indene derivatives with up to
Leah Bantel   +3 more
wiley   +1 more source

Activation of Aryl Halides by Triplet–Triplet Annihilation Upconversion Enabling Coupling Processes Under an Open‐to‐Air Environment

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Triplet–triplet annihilation upconversion (TTA‐UC) performed inside supramolecular viscoelastic gels enables efficient CC and C–heteroatom coupling reactions under green LED irradiation in open‐air conditions. The gel network restricts oxygen diffusion, preserves triplet states, and allows aryl halide activation through upconverted excited states ...
Daniel Álvarez‐Gutiérrez   +4 more
wiley   +1 more source

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