Effects of oxidized low density lipoprotein, lipid mediators and statins on vascular cell interactions [PDF]
, 1999 The integrin heterodimer CD11b/CD18 (alpha M beta 2, Mac-1, CR3) expressed on monocytes or polymorphonuclear leukocytes (PMN) is a receptor for iC3b, fibrinogen, heparin, and for intercellular adhesion molecule (ICAM)-1 on endothelium, crucially ...
Amatruda TT +28 more
core +1 more source
CNS Neuroscience &Therapeutics, Volume 30, Issue 12, December 2024.Bmal1 regulates the pyroptosis pathway after spinal cord injury. Bmal1 inhibits the NF‐κB/MMP9 signaling pathway, reduces inflammatory response, and ultimately inhibits pyroptosis in mice spinal cord injury models. ABSTRACT Background The treatment of spinal cord injury (SCI) is usually ineffective, because neuroinflammatory secondary injury is an ...
Dachuan Li +11 more
wiley +1 more source
Evaluation and Determination of Heavy Metals (Mercury, Lead and Cadmium) in Human Breast Milk
E3S Web of Conferences, 2014 Mercury, Lead and Cadmium were determined in 100 samples of human breast milk samples from urban and rural mothers in Isfahan (IRAN). A questionnaire about area of residence, nutrition, smoking habits, and dental fillings was filled out by the lactating ...
Abdollahi Atousa +2 more
doaj +1 more source
Innovative pathological network‐based multitarget approaches for Alzheimer's disease treatment
Medicinal Research Reviews, Volume 44, Issue 6, Page 2367-2419, November 2024.Abstract Alzheimer's disease (AD) is the most prevalent neurodegenerative disease and is a major health threat globally. Its prevalence is forecasted to exponentially increase during the next 30 years due to the global aging population. Currently, approved drugs are merely symptomatic, being ineffective in delaying or blocking the relentless disease ...
Paloma Mayo +5 more
wiley +1 more source
Improved Method for DNA Extraction and Purification from Tetrahymena pyriformis
Methods and Protocols, 2019 Tetrahymena pyriformis (protozoa) is intensely investigated as a model organism, offering numerous advantages in comprehensive and multidisciplinary studies using morphologic or molecular methods.
Ezzouhra El Maaiden +4 more
doaj +1 more source
Cardiac-specific suppression of NF-kappa B signaling prevents diabetic cardiomyopathy via inhibition of the renin-angiotensin system [PDF]
, 2014 Activation of NF-kappa B signaling in the heart may be protective or deleterious depending on the pathological context. in diabetes, the role of NF-kappa B in cardiac dysfunction has been investigated using pharmacological approaches that have a ...
Baker, Kenneth M. +9 more
core +2 more sources
Perplexing Coordination Behaviour of Potentially Bridging Bipyridyl-Type Ligands in the Coordination Chemistry of Zinc and Cadmium 1,1-Dithiolate Compounds [PDF]
, 2018 The X-ray structural chemistry of zinc and cadmium 1,1-dithiolates (for example, xanthate, dithiophosphate and dithiocarbamate) with potentially bridging bipyridyl-type ligands (for example, 4,40-bipyridine) is reviewed.
Tiekink, Edward R. T. *
core +1 more source
JMJD3 promotes survival of diffuse large B-cell lymphoma subtypes via distinct mechanisms. [PDF]
, 2016 JMJD3 (Jumonji domain containing-3), a histone H3 Lys27 (H3K27) demethylase, has been reported to be involved in the antigen-driven differentiation of germinal center B-cells.
Bai, Nan +10 more
core +1 more source
An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]
, 2018 Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
core +1 more source
Journal of Analytical Methods in Chemistry, 2013 Simple and robust analytical procedures were developed for hexavalent chromium (Cr(VI)) and lead (Pb(II)) by dispersive liquid-liquid microextraction (DLLME) using microsample injection system coupled with flame atomic absorption spectrophotometry (MIS ...
Jameel Ahmed Baig +5 more
doaj +1 more source